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Optimization of Ordered Subset Expectation Maximization Reconstruction for Reducing Urinary Bladder Artifacts in Single-photon Emission Computed Tomography Imaging.

Katua AM, Ankrah AO, Vorster M, van Gelder A, Sathekge MM - World J Nucl Med (2011)

Bottom Line: Four iterations and 8 subsets yielded the best results in 48.5% of the images, whilst 2 iterations and 8 subsets yielded the best results in 33.8%.The number of reconstructed images which yielded the best results with 2 iterations and 8 subsets was the same as or more than those with 4 iterations and 8 subsets when the bladder/acetabulum ratio (A/B) was between 0.2 and 0.39.FBP) leads to better lesion detectability and characterization.

View Article: PubMed Central - PubMed

Affiliation: Department of Nuclear Medicine, University of Pretoria and Steve Biko Academic Hospital, Pretoria, South Africa.

ABSTRACT
Bladder artifact during bone single-photon emission computed tomography (SPECT) is a common source of error. The extent and severity of bladder artifacts have been described for filtered back projection (FBP) reconstruction. Ordered subset expectation maximization (OSEM) may help to address this problem of bladder artifacts, which render up to 20% of the SPECT images unreadable. The objective of this study was to evaluate the relationship of the bladder to acetabulum ratio in guiding the choice of the number of iterations and subsets used for OSEM reconstruction, for reducing bladder artifacts found on FBP reconstruction. One hundred five patients with various indications for bone scans were selected and planar and SPECT images were acquired. The SPECT images were reconstructed with both FBP and OSEM using four different combinations of iterations and subsets. The images were given to three experienced nuclear physicians who were blinded to the diagnosis and type of reconstruction used. They then labeled images from the best to the worst after which the data were analyzed. The bladder to acetabulum ratio for each image was determined which was then correlated with the different iterations and subsets used. The study demonstrated that reconstruction using OSEM led to better lesion detectability compared to FBP in 87.62% of cases. It further demonstrated that the iterations and subsets used for reconstruction of an image correlate with the bladder to acetabulum ratio. Four iterations and 8 subsets yielded the best results in 48.5% of the images, whilst 2 iterations and 8 subsets yielded the best results in 33.8%. The number of reconstructed images which yielded the best results with 2 iterations and 8 subsets was the same as or more than those with 4 iterations and 8 subsets when the bladder/acetabulum ratio (A/B) was between 0.2 and 0.39. A ratio below 0.2 or above 0.39 supports the usage of 4 iterations and 8 subsets over 2 iterations and 8 subsets. We conclude that bladder to acetabulum ratio can be used to select the optimum number of iterations and subsets for reconstruction of bone SPECT for accurate characterization of lesions. This study also confirms that reconstruction with OSEM (vs. FBP) leads to better lesion detectability and characterization.

No MeSH data available.


Relationship between iterations and subsets used for reconstruction versus Acetabulum/Bladder (A/B) ratio
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Figure 2: Relationship between iterations and subsets used for reconstruction versus Acetabulum/Bladder (A/B) ratio

Mentions: One hundred and five patients (59 females and 46 males) were studied. The average age was 55 years, with a standard deviation of 15 years. It was observed that out of the 105 images reconstructed using FBP reconstruction method, only 13 images (12.38%) were rated as grade 4 high-quality images. Hence, the remaining 92 images were reconstructed using OSEM method of reconstruction, which resulted in high-quality (grade 4) images. Reconstruction of imaging using OSEM led to better lesion detectability compared to FBP in all 92 cases. It further demonstrated that the iterations and subsets used for reconstruction of an image correlate with the A/B ratio. Four iterations and 8 subsets yielded the best results in 48.5% of the images, whilst 2 iterations and 8 subsets yielded the best results in 33.8% [Table 2]. The number of reconstructed images which yielded the best results with 2 iterations and 8 subsets was the same as or more than those with 4 iterations and 8 subsets when the A/B ratio was between 0.2 and 0.39. A ratio below 0.2 or above 0.39 supported the use of 8 iterations and 4 subsets over 8 iterations and 2 subsets. Although less common, should the ratio be above 0.69, then 12 iterations and 3 subsets will provide image qualities of grade 3 and 4 [Figure 2].


Optimization of Ordered Subset Expectation Maximization Reconstruction for Reducing Urinary Bladder Artifacts in Single-photon Emission Computed Tomography Imaging.

Katua AM, Ankrah AO, Vorster M, van Gelder A, Sathekge MM - World J Nucl Med (2011)

Relationship between iterations and subsets used for reconstruction versus Acetabulum/Bladder (A/B) ratio
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3198040&req=5

Figure 2: Relationship between iterations and subsets used for reconstruction versus Acetabulum/Bladder (A/B) ratio
Mentions: One hundred and five patients (59 females and 46 males) were studied. The average age was 55 years, with a standard deviation of 15 years. It was observed that out of the 105 images reconstructed using FBP reconstruction method, only 13 images (12.38%) were rated as grade 4 high-quality images. Hence, the remaining 92 images were reconstructed using OSEM method of reconstruction, which resulted in high-quality (grade 4) images. Reconstruction of imaging using OSEM led to better lesion detectability compared to FBP in all 92 cases. It further demonstrated that the iterations and subsets used for reconstruction of an image correlate with the A/B ratio. Four iterations and 8 subsets yielded the best results in 48.5% of the images, whilst 2 iterations and 8 subsets yielded the best results in 33.8% [Table 2]. The number of reconstructed images which yielded the best results with 2 iterations and 8 subsets was the same as or more than those with 4 iterations and 8 subsets when the A/B ratio was between 0.2 and 0.39. A ratio below 0.2 or above 0.39 supported the use of 8 iterations and 4 subsets over 8 iterations and 2 subsets. Although less common, should the ratio be above 0.69, then 12 iterations and 3 subsets will provide image qualities of grade 3 and 4 [Figure 2].

Bottom Line: Four iterations and 8 subsets yielded the best results in 48.5% of the images, whilst 2 iterations and 8 subsets yielded the best results in 33.8%.The number of reconstructed images which yielded the best results with 2 iterations and 8 subsets was the same as or more than those with 4 iterations and 8 subsets when the bladder/acetabulum ratio (A/B) was between 0.2 and 0.39.FBP) leads to better lesion detectability and characterization.

View Article: PubMed Central - PubMed

Affiliation: Department of Nuclear Medicine, University of Pretoria and Steve Biko Academic Hospital, Pretoria, South Africa.

ABSTRACT
Bladder artifact during bone single-photon emission computed tomography (SPECT) is a common source of error. The extent and severity of bladder artifacts have been described for filtered back projection (FBP) reconstruction. Ordered subset expectation maximization (OSEM) may help to address this problem of bladder artifacts, which render up to 20% of the SPECT images unreadable. The objective of this study was to evaluate the relationship of the bladder to acetabulum ratio in guiding the choice of the number of iterations and subsets used for OSEM reconstruction, for reducing bladder artifacts found on FBP reconstruction. One hundred five patients with various indications for bone scans were selected and planar and SPECT images were acquired. The SPECT images were reconstructed with both FBP and OSEM using four different combinations of iterations and subsets. The images were given to three experienced nuclear physicians who were blinded to the diagnosis and type of reconstruction used. They then labeled images from the best to the worst after which the data were analyzed. The bladder to acetabulum ratio for each image was determined which was then correlated with the different iterations and subsets used. The study demonstrated that reconstruction using OSEM led to better lesion detectability compared to FBP in 87.62% of cases. It further demonstrated that the iterations and subsets used for reconstruction of an image correlate with the bladder to acetabulum ratio. Four iterations and 8 subsets yielded the best results in 48.5% of the images, whilst 2 iterations and 8 subsets yielded the best results in 33.8%. The number of reconstructed images which yielded the best results with 2 iterations and 8 subsets was the same as or more than those with 4 iterations and 8 subsets when the bladder/acetabulum ratio (A/B) was between 0.2 and 0.39. A ratio below 0.2 or above 0.39 supports the usage of 4 iterations and 8 subsets over 2 iterations and 8 subsets. We conclude that bladder to acetabulum ratio can be used to select the optimum number of iterations and subsets for reconstruction of bone SPECT for accurate characterization of lesions. This study also confirms that reconstruction with OSEM (vs. FBP) leads to better lesion detectability and characterization.

No MeSH data available.