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A rare benign disorder mimicking metastasis on radiographic examination: a case report of osteopoikilosis.

Ozdemirel AE, Cakit BD, Erdem HR, Koc B - Rheumatol. Int. (2010)

Bottom Line: Osteopoikilosis (OPK) is a rare, autosomal dominant bone disorder, characterized by multiple, discrete round or ovoid radio densities scattered throughout the axial and appendicular skeleton.OPK is usually asymptomatic but rarely there may be slight articular pain and joint effusions.In this case report, we present a young man with right hip pain due to OPK, whose plain radiogram and computerized tomography findings thought cancer metastasis.

View Article: PubMed Central - PubMed

Affiliation: 2nd Department of Physical Medicine and Rehabilitation, Ankara Training and Research Hospital, Ankara, Turkey. erhanozdemirel@hotmail.com

ABSTRACT
Osteopoikilosis (OPK) is a rare, autosomal dominant bone disorder, characterized by multiple, discrete round or ovoid radio densities scattered throughout the axial and appendicular skeleton. OPK is usually asymptomatic but rarely there may be slight articular pain and joint effusions. OPK is generally diagnosed incidentally on radiographic examinations and may mimic different bone pathologies, including bone metastases. Radionuclide bone scan has a critical role in distinguishing OPK from osteoblastic bone metastases. In this case report, we present a young man with right hip pain due to OPK, whose plain radiogram and computerized tomography findings thought cancer metastasis.

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Related in: MedlinePlus

Tc-99m bone scintigraphy image of the patient showing kidney fusion anomaly
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Fig3: Tc-99m bone scintigraphy image of the patient showing kidney fusion anomaly

Mentions: Pelvis radiogram revealed numerous small round foci of bony sclerosis on the upper heads of the femur and acetabulum (Fig. 1). Computerized tomography (CT) examination of pelvis confirmed multiple round sclerotic nodular lesions located in both iliac wings and sacrum, which were mimicking metastases (Fig. 2). Whole body bone scintigraphy was performed to rule out metastases. Tc-99m bone scintigraphy revealed normal findings. But incidentally kidney fusion anomaly was observed in scintigraphic images (Fig. 3). This anomaly was confirmed with urinary system ultrasonography as well. OPK was suspected from these findings, wrist radiogram which revealed multiple symmetric foci of dense radio-opaque spots in the metaphyses of distal radius and ulna, carpal bones, metacarpals and phalanges confirmed the diagnosis (Fig. 4). These radio-opaque spots are also detected on shoulder radiogram (Fig. 5).Fig. 1


A rare benign disorder mimicking metastasis on radiographic examination: a case report of osteopoikilosis.

Ozdemirel AE, Cakit BD, Erdem HR, Koc B - Rheumatol. Int. (2010)

Tc-99m bone scintigraphy image of the patient showing kidney fusion anomaly
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC3141847&req=5

Fig3: Tc-99m bone scintigraphy image of the patient showing kidney fusion anomaly
Mentions: Pelvis radiogram revealed numerous small round foci of bony sclerosis on the upper heads of the femur and acetabulum (Fig. 1). Computerized tomography (CT) examination of pelvis confirmed multiple round sclerotic nodular lesions located in both iliac wings and sacrum, which were mimicking metastases (Fig. 2). Whole body bone scintigraphy was performed to rule out metastases. Tc-99m bone scintigraphy revealed normal findings. But incidentally kidney fusion anomaly was observed in scintigraphic images (Fig. 3). This anomaly was confirmed with urinary system ultrasonography as well. OPK was suspected from these findings, wrist radiogram which revealed multiple symmetric foci of dense radio-opaque spots in the metaphyses of distal radius and ulna, carpal bones, metacarpals and phalanges confirmed the diagnosis (Fig. 4). These radio-opaque spots are also detected on shoulder radiogram (Fig. 5).Fig. 1

Bottom Line: Osteopoikilosis (OPK) is a rare, autosomal dominant bone disorder, characterized by multiple, discrete round or ovoid radio densities scattered throughout the axial and appendicular skeleton.OPK is usually asymptomatic but rarely there may be slight articular pain and joint effusions.In this case report, we present a young man with right hip pain due to OPK, whose plain radiogram and computerized tomography findings thought cancer metastasis.

View Article: PubMed Central - PubMed

Affiliation: 2nd Department of Physical Medicine and Rehabilitation, Ankara Training and Research Hospital, Ankara, Turkey. erhanozdemirel@hotmail.com

ABSTRACT
Osteopoikilosis (OPK) is a rare, autosomal dominant bone disorder, characterized by multiple, discrete round or ovoid radio densities scattered throughout the axial and appendicular skeleton. OPK is usually asymptomatic but rarely there may be slight articular pain and joint effusions. OPK is generally diagnosed incidentally on radiographic examinations and may mimic different bone pathologies, including bone metastases. Radionuclide bone scan has a critical role in distinguishing OPK from osteoblastic bone metastases. In this case report, we present a young man with right hip pain due to OPK, whose plain radiogram and computerized tomography findings thought cancer metastasis.

Show MeSH
Related in: MedlinePlus