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Giant condyloma acuminatum of the scrotum in a man with AIDS: a case report.

Nthumba PM, Ngure P, Nyoro P - J Med Case Rep (2011)

Bottom Line: Scrotal tumors are rare.Decision making regarding the goals of surgical intervention in the terminally ill is a complex process.The challenges presented by emerging or unusual presentations of surgical pathology secondary to HIV and AIDS in patients who are on anti-retroviral therapy provide an opportunity for research and the establishment of guidelines for the use of adjuvant chemotherapy in these patients.

View Article: PubMed Central - HTML - PubMed

Affiliation: Plastic, Reconstructive and Hand Surgery Unit, AIC Kijabe Hospital, Kijabe 00220, Kenya. nthumba@gmail.com.

ABSTRACT

Introduction: Giant condyloma acuminatum, also called a Buschke-Löwenstein tumor, first described in 1925, is a slow-growing, locally aggressive, destructive tumor of the ano-genital region. Scrotal tumors are rare. Reports on giant condyloma acuminatum lesions in patients with HIV and AIDS are surprisingly even rarer.

Case presentation: In this report, we present the case of a 42-year-old African man with AIDS who was undergoing anti-retroviral therapy. He was found to have a giant condyloma acuminatum of the scrotum. Wide surgical excision and scrotal reconstruction with a pedicled anterolateral thigh flap was performed, significantly improving his quality of life.

Conclusion: Decision making regarding the goals of surgical intervention in the terminally ill is a complex process. The options include conservative medical palliation or palliative excision versus a curative excision that has the potential for significant morbidity. Wide surgical excision with local flap reconstruction significantly improved the quality of life of the patient described herein. The challenges presented by emerging or unusual presentations of surgical pathology secondary to HIV and AIDS in patients who are on anti-retroviral therapy provide an opportunity for research and the establishment of guidelines for the use of adjuvant chemotherapy in these patients.

No MeSH data available.


Related in: MedlinePlus

Giant condyloma acuminatum of the scrotum. Note multiple ulcers and discharging sinuses on the scrotum, thigh, and suprapubic areas.
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Figure 1: Giant condyloma acuminatum of the scrotum. Note multiple ulcers and discharging sinuses on the scrotum, thigh, and suprapubic areas.

Mentions: A 42-year-old African man was referred to our institution from another country with a large scrotal tumor first noted five years prior to his presentation to our institution. The mass had grown slowly over the years, with ulceration associated with foul-smelling discharge noted with time, along with seepage of urine from multiple fistuli in the growing scrotal mass (Figure 1). He had been diagnosed with HIV, and ARV therapy had been started two years prior to the development of the scrotal mass. He also had the wasting syndrome, an AIDS-defining diagnosis. He had been unable to walk for three years prior to his visit to our institution. He had been married, but was separated from his wife upon developing the scrotal tumor.


Giant condyloma acuminatum of the scrotum in a man with AIDS: a case report.

Nthumba PM, Ngure P, Nyoro P - J Med Case Rep (2011)

Giant condyloma acuminatum of the scrotum. Note multiple ulcers and discharging sinuses on the scrotum, thigh, and suprapubic areas.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3141715&req=5

Figure 1: Giant condyloma acuminatum of the scrotum. Note multiple ulcers and discharging sinuses on the scrotum, thigh, and suprapubic areas.
Mentions: A 42-year-old African man was referred to our institution from another country with a large scrotal tumor first noted five years prior to his presentation to our institution. The mass had grown slowly over the years, with ulceration associated with foul-smelling discharge noted with time, along with seepage of urine from multiple fistuli in the growing scrotal mass (Figure 1). He had been diagnosed with HIV, and ARV therapy had been started two years prior to the development of the scrotal mass. He also had the wasting syndrome, an AIDS-defining diagnosis. He had been unable to walk for three years prior to his visit to our institution. He had been married, but was separated from his wife upon developing the scrotal tumor.

Bottom Line: Scrotal tumors are rare.Decision making regarding the goals of surgical intervention in the terminally ill is a complex process.The challenges presented by emerging or unusual presentations of surgical pathology secondary to HIV and AIDS in patients who are on anti-retroviral therapy provide an opportunity for research and the establishment of guidelines for the use of adjuvant chemotherapy in these patients.

View Article: PubMed Central - HTML - PubMed

Affiliation: Plastic, Reconstructive and Hand Surgery Unit, AIC Kijabe Hospital, Kijabe 00220, Kenya. nthumba@gmail.com.

ABSTRACT

Introduction: Giant condyloma acuminatum, also called a Buschke-Löwenstein tumor, first described in 1925, is a slow-growing, locally aggressive, destructive tumor of the ano-genital region. Scrotal tumors are rare. Reports on giant condyloma acuminatum lesions in patients with HIV and AIDS are surprisingly even rarer.

Case presentation: In this report, we present the case of a 42-year-old African man with AIDS who was undergoing anti-retroviral therapy. He was found to have a giant condyloma acuminatum of the scrotum. Wide surgical excision and scrotal reconstruction with a pedicled anterolateral thigh flap was performed, significantly improving his quality of life.

Conclusion: Decision making regarding the goals of surgical intervention in the terminally ill is a complex process. The options include conservative medical palliation or palliative excision versus a curative excision that has the potential for significant morbidity. Wide surgical excision with local flap reconstruction significantly improved the quality of life of the patient described herein. The challenges presented by emerging or unusual presentations of surgical pathology secondary to HIV and AIDS in patients who are on anti-retroviral therapy provide an opportunity for research and the establishment of guidelines for the use of adjuvant chemotherapy in these patients.

No MeSH data available.


Related in: MedlinePlus