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Mycetoma: Nonvenereal perineal lesions.

Gupta S, Jain K, Parmar C, Shah P, Raval RC - Indian J Sex Transm Dis (2010)

Bottom Line: Although this is not the thumbrule, there are exceptional reports too.As trauma favors infection, most lesions are on the foot and lower leg but they may occur anywhere on the body mimicking actinomycosis.However, lab investigations and culture are important tool to differentiate apart from the clinical picture.

View Article: PubMed Central - PubMed

Affiliation: Department of Skin and VD, V.S. General Hospital, Ahmedabad 380 006, Gujarat, India.

ABSTRACT
Mycetoma is a chronic, granulomatous disease of the skin, and subcutaneous tissue, which sometimes involves muscle, bones, and neighboring organs. It is characterized by tumefaction, abscess formation, and fistulae with discharge of grains from sinuses. Mycetoma can be caused by various species of fungi (eumycetoma) and aerobic actinomycetes (actinomycetoma), which occur as saprophytes in soil or plants. A tentative diagnosis sufficient to initiate treatment may be made on the basis of grain color. For instance, melanoid grains are always caused by fungi and ochroid or pale grains by actinomycetes. Although this is not the thumbrule, there are exceptional reports too. As trauma favors infection, most lesions are on the foot and lower leg but they may occur anywhere on the body mimicking actinomycosis. However, lab investigations and culture are important tool to differentiate apart from the clinical picture. We are reporting atypical case with unusual site of presentation (perineum and thigh) of mycetoma.

No MeSH data available.


Related in: MedlinePlus

Madurella mycetomatis in Sabouraud’s dextrose agar (two cultured specimens of patient) with leathery colony and brown pigment production compared with control
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Figure 0004: Madurella mycetomatis in Sabouraud’s dextrose agar (two cultured specimens of patient) with leathery colony and brown pigment production compared with control

Mentions: The KOH mount of the granule revealed thin long-branched hyphae with well-defined walls. The punch biopsy of the nodule on histopathological examination revealed dermis with mixed inflammatory cell infilterate mainly of the polymorphs and lymphocytes. There were neutrophilic abcesses with organized aggregates of filaments [Figure 3] and 1% AFB revealed no acid fast filaments. On Gram stain of the granule, fungal elements were present in the granules. On culture of the granules (washed with sterile saline and inoculated on to Sabouraud’s dextrose agar) revealed the organism to be Madurella mycetomatis [Figure 4].


Mycetoma: Nonvenereal perineal lesions.

Gupta S, Jain K, Parmar C, Shah P, Raval RC - Indian J Sex Transm Dis (2010)

Madurella mycetomatis in Sabouraud’s dextrose agar (two cultured specimens of patient) with leathery colony and brown pigment production compared with control
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3140148&req=5

Figure 0004: Madurella mycetomatis in Sabouraud’s dextrose agar (two cultured specimens of patient) with leathery colony and brown pigment production compared with control
Mentions: The KOH mount of the granule revealed thin long-branched hyphae with well-defined walls. The punch biopsy of the nodule on histopathological examination revealed dermis with mixed inflammatory cell infilterate mainly of the polymorphs and lymphocytes. There were neutrophilic abcesses with organized aggregates of filaments [Figure 3] and 1% AFB revealed no acid fast filaments. On Gram stain of the granule, fungal elements were present in the granules. On culture of the granules (washed with sterile saline and inoculated on to Sabouraud’s dextrose agar) revealed the organism to be Madurella mycetomatis [Figure 4].

Bottom Line: Although this is not the thumbrule, there are exceptional reports too.As trauma favors infection, most lesions are on the foot and lower leg but they may occur anywhere on the body mimicking actinomycosis.However, lab investigations and culture are important tool to differentiate apart from the clinical picture.

View Article: PubMed Central - PubMed

Affiliation: Department of Skin and VD, V.S. General Hospital, Ahmedabad 380 006, Gujarat, India.

ABSTRACT
Mycetoma is a chronic, granulomatous disease of the skin, and subcutaneous tissue, which sometimes involves muscle, bones, and neighboring organs. It is characterized by tumefaction, abscess formation, and fistulae with discharge of grains from sinuses. Mycetoma can be caused by various species of fungi (eumycetoma) and aerobic actinomycetes (actinomycetoma), which occur as saprophytes in soil or plants. A tentative diagnosis sufficient to initiate treatment may be made on the basis of grain color. For instance, melanoid grains are always caused by fungi and ochroid or pale grains by actinomycetes. Although this is not the thumbrule, there are exceptional reports too. As trauma favors infection, most lesions are on the foot and lower leg but they may occur anywhere on the body mimicking actinomycosis. However, lab investigations and culture are important tool to differentiate apart from the clinical picture. We are reporting atypical case with unusual site of presentation (perineum and thigh) of mycetoma.

No MeSH data available.


Related in: MedlinePlus