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Disseminated histoplasmosis with conjunctival involvement in an immunocompromised patient.

Shirali A, Kini J, Vupputuri A, Kuruvila M, Prabhu MV - Indian J Sex Transm Dis (2010)

Bottom Line: The patient presented with high-grade fever, cough, conjunctival nodule and papulonodular hyperpigmented skin lesions.Bone marrow aspirate confirmed disseminated histoplasmosis.The patient showed dramatic response after starting treatment with Amphotercin B.

View Article: PubMed Central - PubMed

Affiliation: Department of Medicine, Kasturba Medical College, Mangalore, Karnataka, India.

ABSTRACT
We report a case of disseminated histoplasmosis in a 37-year-old male acquired immunodeficiency syndrome patient from south India. The patient presented with high-grade fever, cough, conjunctival nodule and papulonodular hyperpigmented skin lesions. Histology of skin lesions and conjunctival nodule showed numerous intracellular Periodic Acid Schiff-positive rounded yeast cells within macrophages. Bone marrow aspirate confirmed disseminated histoplasmosis. The patient showed dramatic response after starting treatment with Amphotercin B.

No MeSH data available.


Related in: MedlinePlus

Histopathological section of the conjunctival specimen showing numerous macrophage aggregates with Period Acid Schiff (PAS)-positive histoplasma (PAS stain, ×100)
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Figure 0004: Histopathological section of the conjunctival specimen showing numerous macrophage aggregates with Period Acid Schiff (PAS)-positive histoplasma (PAS stain, ×100)

Mentions: Histopathological examination of the conjunctival specimen showed numerous macrophage aggregates with 2–4 mm PAS-positive yeast-like forms of H. capsulatum [Figure 4].


Disseminated histoplasmosis with conjunctival involvement in an immunocompromised patient.

Shirali A, Kini J, Vupputuri A, Kuruvila M, Prabhu MV - Indian J Sex Transm Dis (2010)

Histopathological section of the conjunctival specimen showing numerous macrophage aggregates with Period Acid Schiff (PAS)-positive histoplasma (PAS stain, ×100)
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3140147&req=5

Figure 0004: Histopathological section of the conjunctival specimen showing numerous macrophage aggregates with Period Acid Schiff (PAS)-positive histoplasma (PAS stain, ×100)
Mentions: Histopathological examination of the conjunctival specimen showed numerous macrophage aggregates with 2–4 mm PAS-positive yeast-like forms of H. capsulatum [Figure 4].

Bottom Line: The patient presented with high-grade fever, cough, conjunctival nodule and papulonodular hyperpigmented skin lesions.Bone marrow aspirate confirmed disseminated histoplasmosis.The patient showed dramatic response after starting treatment with Amphotercin B.

View Article: PubMed Central - PubMed

Affiliation: Department of Medicine, Kasturba Medical College, Mangalore, Karnataka, India.

ABSTRACT
We report a case of disseminated histoplasmosis in a 37-year-old male acquired immunodeficiency syndrome patient from south India. The patient presented with high-grade fever, cough, conjunctival nodule and papulonodular hyperpigmented skin lesions. Histology of skin lesions and conjunctival nodule showed numerous intracellular Periodic Acid Schiff-positive rounded yeast cells within macrophages. Bone marrow aspirate confirmed disseminated histoplasmosis. The patient showed dramatic response after starting treatment with Amphotercin B.

No MeSH data available.


Related in: MedlinePlus