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Disseminated histoplasmosis with conjunctival involvement in an immunocompromised patient.

Shirali A, Kini J, Vupputuri A, Kuruvila M, Prabhu MV - Indian J Sex Transm Dis (2010)

Bottom Line: The patient presented with high-grade fever, cough, conjunctival nodule and papulonodular hyperpigmented skin lesions.Bone marrow aspirate confirmed disseminated histoplasmosis.The patient showed dramatic response after starting treatment with Amphotercin B.

View Article: PubMed Central - PubMed

Affiliation: Department of Medicine, Kasturba Medical College, Mangalore, Karnataka, India.

ABSTRACT
We report a case of disseminated histoplasmosis in a 37-year-old male acquired immunodeficiency syndrome patient from south India. The patient presented with high-grade fever, cough, conjunctival nodule and papulonodular hyperpigmented skin lesions. Histology of skin lesions and conjunctival nodule showed numerous intracellular Periodic Acid Schiff-positive rounded yeast cells within macrophages. Bone marrow aspirate confirmed disseminated histoplasmosis. The patient showed dramatic response after starting treatment with Amphotercin B.

No MeSH data available.


Related in: MedlinePlus

Conjunctival nodule with congestion in the right eye
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Figure 0002: Conjunctival nodule with congestion in the right eye

Mentions: On examination, he had multiple, discrete, mildly tender, hyperpigmented, papulonodular lesions, distributed over the face [Figure 1], neck, chest, back and oral cavity. Some of them showed ulcerations and crusting. A bright red, elevated, non-mobile, bulbar conjunctival nodule with congestion was present in the right eye [Figure 2]. He had generalized lymphadenopathy and non-tender hepatomegaly. Examination of the respiratory system revealed bilateral coarse crackles. Other systemic examination and fundus examination were unremarkable.


Disseminated histoplasmosis with conjunctival involvement in an immunocompromised patient.

Shirali A, Kini J, Vupputuri A, Kuruvila M, Prabhu MV - Indian J Sex Transm Dis (2010)

Conjunctival nodule with congestion in the right eye
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3140147&req=5

Figure 0002: Conjunctival nodule with congestion in the right eye
Mentions: On examination, he had multiple, discrete, mildly tender, hyperpigmented, papulonodular lesions, distributed over the face [Figure 1], neck, chest, back and oral cavity. Some of them showed ulcerations and crusting. A bright red, elevated, non-mobile, bulbar conjunctival nodule with congestion was present in the right eye [Figure 2]. He had generalized lymphadenopathy and non-tender hepatomegaly. Examination of the respiratory system revealed bilateral coarse crackles. Other systemic examination and fundus examination were unremarkable.

Bottom Line: The patient presented with high-grade fever, cough, conjunctival nodule and papulonodular hyperpigmented skin lesions.Bone marrow aspirate confirmed disseminated histoplasmosis.The patient showed dramatic response after starting treatment with Amphotercin B.

View Article: PubMed Central - PubMed

Affiliation: Department of Medicine, Kasturba Medical College, Mangalore, Karnataka, India.

ABSTRACT
We report a case of disseminated histoplasmosis in a 37-year-old male acquired immunodeficiency syndrome patient from south India. The patient presented with high-grade fever, cough, conjunctival nodule and papulonodular hyperpigmented skin lesions. Histology of skin lesions and conjunctival nodule showed numerous intracellular Periodic Acid Schiff-positive rounded yeast cells within macrophages. Bone marrow aspirate confirmed disseminated histoplasmosis. The patient showed dramatic response after starting treatment with Amphotercin B.

No MeSH data available.


Related in: MedlinePlus