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Askin's Tumor: A Dual Case Study.

Shrestha B, Kapur BN, Karmacharya K, Kakkar S, Ghuliani R - Int J Pediatr (2011)

Bottom Line: Askin's tumor is a rare tumor arising from the chest wall.It is a subset of Ewing sarcoma characterized histologically by the presence of small round blue cells.A dual paper of Askin's tumors in young boys is being presented here.

View Article: PubMed Central - PubMed

Affiliation: Department of Pediatrics, Armed Forces Medical College, Pune, India.

ABSTRACT
Askin's tumor is a rare tumor arising from the chest wall. It is a subset of Ewing sarcoma characterized histologically by the presence of small round blue cells. It is a highly malignant tumor with guarded prognosis, which is dependent upon the extension of tumor at the time of diagnosis. A dual paper of Askin's tumors in young boys is being presented here.

No MeSH data available.


Related in: MedlinePlus

Chest X ray postsurgery in Case 2.
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Related In: Results  -  Collection


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fig5: Chest X ray postsurgery in Case 2.

Mentions: He was given chemotherapy with vincristine, adriamycin and cyclophosphamide (VAC), alternating with ifosfamide and etoposide (IE) as per RCT II protocol [3]. After completion of 4 cycles, the mass showed significant regression. Postchemotherapy, he was taken up for surgery. Per operatively the tumor mass was seen on parietal pleura, extending from the 5th to the 8th ribs and adherent to the chest wall. Wide local excision with en bloc excision of the 5th, 6th, 7th, and 8th ribs was done, leaving behind a clear 2 cm healthy margin. The resected region was reconstructed with bone cement and prolene mesh. The chest radiograph PA view postsurgery is shown (Figure 5). After successful surgery, he was put on alternating cycles of vincristine, adriamycin and cyclophosphamide (VAC) alternating with cyclophosphamide, vincristine, and dactinomycin (CVD). Presently, he has completed 6 cycles of chemotherapy and has remained relapse-free and asymptomatic. We plan to continue chemotherapy to complete 12 cycles and reevaluate further then.


Askin's Tumor: A Dual Case Study.

Shrestha B, Kapur BN, Karmacharya K, Kakkar S, Ghuliani R - Int J Pediatr (2011)

Chest X ray postsurgery in Case 2.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC3139879&req=5

fig5: Chest X ray postsurgery in Case 2.
Mentions: He was given chemotherapy with vincristine, adriamycin and cyclophosphamide (VAC), alternating with ifosfamide and etoposide (IE) as per RCT II protocol [3]. After completion of 4 cycles, the mass showed significant regression. Postchemotherapy, he was taken up for surgery. Per operatively the tumor mass was seen on parietal pleura, extending from the 5th to the 8th ribs and adherent to the chest wall. Wide local excision with en bloc excision of the 5th, 6th, 7th, and 8th ribs was done, leaving behind a clear 2 cm healthy margin. The resected region was reconstructed with bone cement and prolene mesh. The chest radiograph PA view postsurgery is shown (Figure 5). After successful surgery, he was put on alternating cycles of vincristine, adriamycin and cyclophosphamide (VAC) alternating with cyclophosphamide, vincristine, and dactinomycin (CVD). Presently, he has completed 6 cycles of chemotherapy and has remained relapse-free and asymptomatic. We plan to continue chemotherapy to complete 12 cycles and reevaluate further then.

Bottom Line: Askin's tumor is a rare tumor arising from the chest wall.It is a subset of Ewing sarcoma characterized histologically by the presence of small round blue cells.A dual paper of Askin's tumors in young boys is being presented here.

View Article: PubMed Central - PubMed

Affiliation: Department of Pediatrics, Armed Forces Medical College, Pune, India.

ABSTRACT
Askin's tumor is a rare tumor arising from the chest wall. It is a subset of Ewing sarcoma characterized histologically by the presence of small round blue cells. It is a highly malignant tumor with guarded prognosis, which is dependent upon the extension of tumor at the time of diagnosis. A dual paper of Askin's tumors in young boys is being presented here.

No MeSH data available.


Related in: MedlinePlus