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Askin's Tumor: A Dual Case Study.

Shrestha B, Kapur BN, Karmacharya K, Kakkar S, Ghuliani R - Int J Pediatr (2011)

Bottom Line: Askin's tumor is a rare tumor arising from the chest wall.It is a subset of Ewing sarcoma characterized histologically by the presence of small round blue cells.A dual paper of Askin's tumors in young boys is being presented here.

View Article: PubMed Central - PubMed

Affiliation: Department of Pediatrics, Armed Forces Medical College, Pune, India.

ABSTRACT
Askin's tumor is a rare tumor arising from the chest wall. It is a subset of Ewing sarcoma characterized histologically by the presence of small round blue cells. It is a highly malignant tumor with guarded prognosis, which is dependent upon the extension of tumor at the time of diagnosis. A dual paper of Askin's tumors in young boys is being presented here.

No MeSH data available.


Related in: MedlinePlus

Histopathlogical examination of the biopsy in Case 2 showing sheets of small round blue cells (×400 magnification).
© Copyright Policy - open-access
Related In: Results  -  Collection


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fig4: Histopathlogical examination of the biopsy in Case 2 showing sheets of small round blue cells (×400 magnification).

Mentions: 9-year-old boy had presented with chest pain and fever of 7 days duration. There was no history of breathlessness, cough, hemoptysis, or weight loss. His past history and family history were unremarkable. Radiograph of the chest PA view showed large homogenous opacity covering almost the entire right hemithorax. CT scan chest delineated a large mass (9.5 cm × 4.5 cm × 7.3 cm) along the right posterolateral chest wall which was causing scalloping of the inner surface of the 8th rib with obliteration of the extrapleural fat in places with free well defined and irregular border medially. FNAC from the lesion showed small round blue cells, with scanty cytoplasm and relatively large nuclei. Biopsy of the lesion showed small round blue cells in sheets with ill-defined rosette-like structures, histomorphologically peripheral neuroectodermal tumor-possibly Askin's tumor (Figure 4). Immunohistochemistry of the tumor cells was CD-99, synaptophysin, chromoganin focal positive, and desmin, SMA, CK, and LCA negative.


Askin's Tumor: A Dual Case Study.

Shrestha B, Kapur BN, Karmacharya K, Kakkar S, Ghuliani R - Int J Pediatr (2011)

Histopathlogical examination of the biopsy in Case 2 showing sheets of small round blue cells (×400 magnification).
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC3139879&req=5

fig4: Histopathlogical examination of the biopsy in Case 2 showing sheets of small round blue cells (×400 magnification).
Mentions: 9-year-old boy had presented with chest pain and fever of 7 days duration. There was no history of breathlessness, cough, hemoptysis, or weight loss. His past history and family history were unremarkable. Radiograph of the chest PA view showed large homogenous opacity covering almost the entire right hemithorax. CT scan chest delineated a large mass (9.5 cm × 4.5 cm × 7.3 cm) along the right posterolateral chest wall which was causing scalloping of the inner surface of the 8th rib with obliteration of the extrapleural fat in places with free well defined and irregular border medially. FNAC from the lesion showed small round blue cells, with scanty cytoplasm and relatively large nuclei. Biopsy of the lesion showed small round blue cells in sheets with ill-defined rosette-like structures, histomorphologically peripheral neuroectodermal tumor-possibly Askin's tumor (Figure 4). Immunohistochemistry of the tumor cells was CD-99, synaptophysin, chromoganin focal positive, and desmin, SMA, CK, and LCA negative.

Bottom Line: Askin's tumor is a rare tumor arising from the chest wall.It is a subset of Ewing sarcoma characterized histologically by the presence of small round blue cells.A dual paper of Askin's tumors in young boys is being presented here.

View Article: PubMed Central - PubMed

Affiliation: Department of Pediatrics, Armed Forces Medical College, Pune, India.

ABSTRACT
Askin's tumor is a rare tumor arising from the chest wall. It is a subset of Ewing sarcoma characterized histologically by the presence of small round blue cells. It is a highly malignant tumor with guarded prognosis, which is dependent upon the extension of tumor at the time of diagnosis. A dual paper of Askin's tumors in young boys is being presented here.

No MeSH data available.


Related in: MedlinePlus