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Askin's Tumor: A Dual Case Study.

Shrestha B, Kapur BN, Karmacharya K, Kakkar S, Ghuliani R - Int J Pediatr (2011)

Bottom Line: Askin's tumor is a rare tumor arising from the chest wall.It is a subset of Ewing sarcoma characterized histologically by the presence of small round blue cells.A dual paper of Askin's tumors in young boys is being presented here.

View Article: PubMed Central - PubMed

Affiliation: Department of Pediatrics, Armed Forces Medical College, Pune, India.

ABSTRACT
Askin's tumor is a rare tumor arising from the chest wall. It is a subset of Ewing sarcoma characterized histologically by the presence of small round blue cells. It is a highly malignant tumor with guarded prognosis, which is dependent upon the extension of tumor at the time of diagnosis. A dual paper of Askin's tumors in young boys is being presented here.

No MeSH data available.


Related in: MedlinePlus

Immunohistochemistry from the lesion showing CK and CD 99 positive in Case 1 (×400 magnification).
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fig3: Immunohistochemistry from the lesion showing CK and CD 99 positive in Case 1 (×400 magnification).

Mentions: The tumor regressed significantly with 8 cycles of chemothearpy. Surgery was undertaken after the course of chemotherapy. Operative findings showed tumor which was arising from the 1st rib, stuck to the apex of the right lung. There was also intense desmoplastic reaction surrounding the tumor, and adhesions were present between the tumor and the right subclavian vessel and superior venacava. Thoracotomy with excision of the tumor and resection of the first rib was done, preserving subclavian vein and brachial plexus. There were no postoperative complications. Postoperative histopathological examination of the mass showed small round blue cell tumors with hyperchromatic nuclei and scanty cytoplasm with tiny foci of calcifications. Immunohistochemistry was strongly positive for CK and CD-99 and negative for LCA and CD-34 (Figure 3).


Askin's Tumor: A Dual Case Study.

Shrestha B, Kapur BN, Karmacharya K, Kakkar S, Ghuliani R - Int J Pediatr (2011)

Immunohistochemistry from the lesion showing CK and CD 99 positive in Case 1 (×400 magnification).
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC3139879&req=5

fig3: Immunohistochemistry from the lesion showing CK and CD 99 positive in Case 1 (×400 magnification).
Mentions: The tumor regressed significantly with 8 cycles of chemothearpy. Surgery was undertaken after the course of chemotherapy. Operative findings showed tumor which was arising from the 1st rib, stuck to the apex of the right lung. There was also intense desmoplastic reaction surrounding the tumor, and adhesions were present between the tumor and the right subclavian vessel and superior venacava. Thoracotomy with excision of the tumor and resection of the first rib was done, preserving subclavian vein and brachial plexus. There were no postoperative complications. Postoperative histopathological examination of the mass showed small round blue cell tumors with hyperchromatic nuclei and scanty cytoplasm with tiny foci of calcifications. Immunohistochemistry was strongly positive for CK and CD-99 and negative for LCA and CD-34 (Figure 3).

Bottom Line: Askin's tumor is a rare tumor arising from the chest wall.It is a subset of Ewing sarcoma characterized histologically by the presence of small round blue cells.A dual paper of Askin's tumors in young boys is being presented here.

View Article: PubMed Central - PubMed

Affiliation: Department of Pediatrics, Armed Forces Medical College, Pune, India.

ABSTRACT
Askin's tumor is a rare tumor arising from the chest wall. It is a subset of Ewing sarcoma characterized histologically by the presence of small round blue cells. It is a highly malignant tumor with guarded prognosis, which is dependent upon the extension of tumor at the time of diagnosis. A dual paper of Askin's tumors in young boys is being presented here.

No MeSH data available.


Related in: MedlinePlus