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Comparison of left ventricular mass in normotensive type 2 diabetes mellitus patients with that in the nondiabetic population.

Santra S, Basu AK, Roychowdhury P, Banerjee R, Singhania P, Singh S, Datta UK - J Cardiovasc Dis Res (2011)

Bottom Line: A total of 130 age- and sex-matched subjects were selected (65 cases, diabetic normotensive, and 65 controls, nondiabetic normotensive) and baseline data were collected.LVMI was significantly higher in patients with type 2 DM compared with age-, sex-matched healthy population (104.9 ± 21 vs. 78.5 ± 22.7 g/m(2), respectively; P < 0.05).BMI, HbA1c, and duration of diabetes were significantly associated with LVH whereas sexes, age, PPBS, were not.

View Article: PubMed Central - PubMed

Affiliation: Department of Medicine, RG Kar Medical College, Kolkata, West Bengal, India.

ABSTRACT
Cardiovascular disease is increased in individuals with type 1 or type 2 diabetes mellitus (DM). Left ventricular hypertrophy (LVH), which is an ominous prognostic sign and an independent risk factor for cardiac events, is often present in type 2 DM patients. The aim of our cross-sectional study was to evaluate the prevalence of LVH, and risk factors for its development, in normotensive type 2 diabetic patients without antihypertensive medication. The objectives of the study were to find out the prevalence of high left ventricular mass (LVM) in normotensive type 2 diabetic patients and compare it with nondiabetics and to uncover the risk factors for the development of high LVM in normotensive type 2 diabetic patients. A total of 130 age- and sex-matched subjects were selected (65 cases, diabetic normotensive, and 65 controls, nondiabetic normotensive) and baseline data were collected. LVM and left ventricular mass index (LVMI) were calculated using echocardigraphic parameters and body surface area. LVMI was significantly higher in patients with type 2 DM compared with age-, sex-matched healthy population (104.9 ± 21 vs. 78.5 ± 22.7 g/m(2), respectively; P < 0.05). BMI, HbA1c, and duration of diabetes were significantly associated with LVH whereas sexes, age, PPBS, were not.

No MeSH data available.


Related in: MedlinePlus

Bar diagram showing prevalence of left ventricular mass in male subjects of Type 2 DM and control patients
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Figure 1: Bar diagram showing prevalence of left ventricular mass in male subjects of Type 2 DM and control patients

Mentions: The prevalence of high LVM and high LVMI in all type 2 DM patients of our study was 44% and 53%, respectively. The prevalence of high LVM and high LVMI in male subjects with type 2 DM was 40% and 54%, respectively [Figure 1,2]. The prevalence of high LVM and high LVMI in female subjects with type 2 DM was 50% and 53%, respectively [Figure 3,4].


Comparison of left ventricular mass in normotensive type 2 diabetes mellitus patients with that in the nondiabetic population.

Santra S, Basu AK, Roychowdhury P, Banerjee R, Singhania P, Singh S, Datta UK - J Cardiovasc Dis Res (2011)

Bar diagram showing prevalence of left ventricular mass in male subjects of Type 2 DM and control patients
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3120273&req=5

Figure 1: Bar diagram showing prevalence of left ventricular mass in male subjects of Type 2 DM and control patients
Mentions: The prevalence of high LVM and high LVMI in all type 2 DM patients of our study was 44% and 53%, respectively. The prevalence of high LVM and high LVMI in male subjects with type 2 DM was 40% and 54%, respectively [Figure 1,2]. The prevalence of high LVM and high LVMI in female subjects with type 2 DM was 50% and 53%, respectively [Figure 3,4].

Bottom Line: A total of 130 age- and sex-matched subjects were selected (65 cases, diabetic normotensive, and 65 controls, nondiabetic normotensive) and baseline data were collected.LVMI was significantly higher in patients with type 2 DM compared with age-, sex-matched healthy population (104.9 ± 21 vs. 78.5 ± 22.7 g/m(2), respectively; P < 0.05).BMI, HbA1c, and duration of diabetes were significantly associated with LVH whereas sexes, age, PPBS, were not.

View Article: PubMed Central - PubMed

Affiliation: Department of Medicine, RG Kar Medical College, Kolkata, West Bengal, India.

ABSTRACT
Cardiovascular disease is increased in individuals with type 1 or type 2 diabetes mellitus (DM). Left ventricular hypertrophy (LVH), which is an ominous prognostic sign and an independent risk factor for cardiac events, is often present in type 2 DM patients. The aim of our cross-sectional study was to evaluate the prevalence of LVH, and risk factors for its development, in normotensive type 2 diabetic patients without antihypertensive medication. The objectives of the study were to find out the prevalence of high left ventricular mass (LVM) in normotensive type 2 diabetic patients and compare it with nondiabetics and to uncover the risk factors for the development of high LVM in normotensive type 2 diabetic patients. A total of 130 age- and sex-matched subjects were selected (65 cases, diabetic normotensive, and 65 controls, nondiabetic normotensive) and baseline data were collected. LVM and left ventricular mass index (LVMI) were calculated using echocardigraphic parameters and body surface area. LVMI was significantly higher in patients with type 2 DM compared with age-, sex-matched healthy population (104.9 ± 21 vs. 78.5 ± 22.7 g/m(2), respectively; P < 0.05). BMI, HbA1c, and duration of diabetes were significantly associated with LVH whereas sexes, age, PPBS, were not.

No MeSH data available.


Related in: MedlinePlus