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Trends in malaria research in 11 Asian Pacific countries: an analysis of peer-reviewed publications over two decades.

Andersen F, Douglas NM, Bustos D, Galappaththy G, Qi G, Hsiang MS, Kusriastuti R, Mendis K, Taleo G, Whittaker M, Price RN, von Seidlein L - Malar. J. (2011)

Bottom Line: The percentage of malaria-related publications was nearly 3% (111/3741) of all biomedical publications in 1992 and decreased to less than 1% (118/12171; p < 0.001) in 2009.The proportion of malaria-related publications out of the overall biomedical output from the 11 target Asian-Pacific countries is decreasing.The discovery and evaluation of new, safe and effective drugs and vaccines is paramount.

View Article: PubMed Central - HTML - PubMed

Affiliation: Global Health Division, Menzies School of Health Research, Casuarina, NT 0811, Australia.

ABSTRACT

Background: Quantitative data are lacking on published malaria research. The purpose of the study is to characterize trends in malaria-related literature from 1990 to 2009 in 11 Asian-Pacific countries that are committed to malaria elimination as a national goal.

Methods: A systematic search was conducted for articles published from January 1990 to December 2009 in PubMed/MEDLINE using terms for malaria and 11 target countries (Bhutan, China, North Korea, Indonesia, Malaysia, Philippines, Solomon Islands, South Korea, Sri Lanka, Thailand and Vanuatu). The references were collated and categorized according to subject, Plasmodium species, and whether they contained original or derivative data.

Results: 2,700 articles published between 1990 and 2009 related to malaria in the target countries. The annual output of malaria-related papers increased linearly whereas the overall biomedical output from these countries grew exponentially. The percentage of malaria-related publications was nearly 3% (111/3741) of all biomedical publications in 1992 and decreased to less than 1% (118/12171; p < 0.001) in 2009. Thailand had the highest absolute output of malaria-related papers (n = 1211), followed by China (n = 609) and Indonesia (n = 346). Solomon Islands and Vanuatu had lower absolute numbers of publications, but both countries had the highest number of publications per capita (1.3 and 2.5 papers/1,000 population). The largest percentage of papers concerned the epidemiology and control of malaria (53%) followed by studies of drugs and drug resistance (47%). There was an increase in the proportion of articles relating to epidemiology, entomology, biology, molecular biology, pathophysiology and diagnostics from the first to the second decade, whereas the percentage of papers on drugs, clinical aspects of malaria, immunology, and social sciences decreased.

Conclusions: The proportion of malaria-related publications out of the overall biomedical output from the 11 target Asian-Pacific countries is decreasing. The discovery and evaluation of new, safe and effective drugs and vaccines is paramount. In addition the elimination of malaria will require operational research to implement and scale up interventions.

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The yearly number of malaria-related and all biomedical publications other than malaria from the 11 target countries, 1990 to 2009.
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Figure 2: The yearly number of malaria-related and all biomedical publications other than malaria from the 11 target countries, 1990 to 2009.

Mentions: To visualize general trends in peer reviewed publications, the number of malaria-related publications was graphed and compared with overall biomedical publications over time (Figure 2). Over the 20-year study period, the number of malaria-related publications rose 2.1 fold in a linear fashion (linear trendline with r2 = 0.66), from 64 per year in 1990 to 136 per year in 2009. In the first decade of analysis 980 malaria-related publications were identified, increasing to 1,242 during the following decade. The proportion of papers reporting original data remained relatively stable throughout the two decades at around 85%. Over the same period the number of biomedical publications relating to the target countries increased exponentially (exponential trendline with r2 = 0.95). The total number of biomedical publications increased from 40,567 in the decade from 1990 through 1999 to 113,714 in the decade from 2000 through 2009. The percentage of malaria-related publications was nearly 3% (111/3,741) of all biomedical publications in 1992 and decreased yearly to less than 1% (118/12,171) by 2005, staying below 1% thereafter (p < 0.001; Figure 3).


Trends in malaria research in 11 Asian Pacific countries: an analysis of peer-reviewed publications over two decades.

Andersen F, Douglas NM, Bustos D, Galappaththy G, Qi G, Hsiang MS, Kusriastuti R, Mendis K, Taleo G, Whittaker M, Price RN, von Seidlein L - Malar. J. (2011)

The yearly number of malaria-related and all biomedical publications other than malaria from the 11 target countries, 1990 to 2009.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3118956&req=5

Figure 2: The yearly number of malaria-related and all biomedical publications other than malaria from the 11 target countries, 1990 to 2009.
Mentions: To visualize general trends in peer reviewed publications, the number of malaria-related publications was graphed and compared with overall biomedical publications over time (Figure 2). Over the 20-year study period, the number of malaria-related publications rose 2.1 fold in a linear fashion (linear trendline with r2 = 0.66), from 64 per year in 1990 to 136 per year in 2009. In the first decade of analysis 980 malaria-related publications were identified, increasing to 1,242 during the following decade. The proportion of papers reporting original data remained relatively stable throughout the two decades at around 85%. Over the same period the number of biomedical publications relating to the target countries increased exponentially (exponential trendline with r2 = 0.95). The total number of biomedical publications increased from 40,567 in the decade from 1990 through 1999 to 113,714 in the decade from 2000 through 2009. The percentage of malaria-related publications was nearly 3% (111/3,741) of all biomedical publications in 1992 and decreased yearly to less than 1% (118/12,171) by 2005, staying below 1% thereafter (p < 0.001; Figure 3).

Bottom Line: The percentage of malaria-related publications was nearly 3% (111/3741) of all biomedical publications in 1992 and decreased to less than 1% (118/12171; p < 0.001) in 2009.The proportion of malaria-related publications out of the overall biomedical output from the 11 target Asian-Pacific countries is decreasing.The discovery and evaluation of new, safe and effective drugs and vaccines is paramount.

View Article: PubMed Central - HTML - PubMed

Affiliation: Global Health Division, Menzies School of Health Research, Casuarina, NT 0811, Australia.

ABSTRACT

Background: Quantitative data are lacking on published malaria research. The purpose of the study is to characterize trends in malaria-related literature from 1990 to 2009 in 11 Asian-Pacific countries that are committed to malaria elimination as a national goal.

Methods: A systematic search was conducted for articles published from January 1990 to December 2009 in PubMed/MEDLINE using terms for malaria and 11 target countries (Bhutan, China, North Korea, Indonesia, Malaysia, Philippines, Solomon Islands, South Korea, Sri Lanka, Thailand and Vanuatu). The references were collated and categorized according to subject, Plasmodium species, and whether they contained original or derivative data.

Results: 2,700 articles published between 1990 and 2009 related to malaria in the target countries. The annual output of malaria-related papers increased linearly whereas the overall biomedical output from these countries grew exponentially. The percentage of malaria-related publications was nearly 3% (111/3741) of all biomedical publications in 1992 and decreased to less than 1% (118/12171; p < 0.001) in 2009. Thailand had the highest absolute output of malaria-related papers (n = 1211), followed by China (n = 609) and Indonesia (n = 346). Solomon Islands and Vanuatu had lower absolute numbers of publications, but both countries had the highest number of publications per capita (1.3 and 2.5 papers/1,000 population). The largest percentage of papers concerned the epidemiology and control of malaria (53%) followed by studies of drugs and drug resistance (47%). There was an increase in the proportion of articles relating to epidemiology, entomology, biology, molecular biology, pathophysiology and diagnostics from the first to the second decade, whereas the percentage of papers on drugs, clinical aspects of malaria, immunology, and social sciences decreased.

Conclusions: The proportion of malaria-related publications out of the overall biomedical output from the 11 target Asian-Pacific countries is decreasing. The discovery and evaluation of new, safe and effective drugs and vaccines is paramount. In addition the elimination of malaria will require operational research to implement and scale up interventions.

Show MeSH
Related in: MedlinePlus