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Population surveillance of dementia mortality.

Gillum RF, Yorrick R, Obisesan TO - Int J Environ Res Public Health (2011)

Bottom Line: Among the states, age-adjusted rates per 100,000 per year varied by two fold ranging from 458 in New York to 921 in Oregon.Similar geographic patterns were seen for Alzheimer's disease.Use of specific (G30, F01) versus non-specific diagnoses (F02, R54) varied among states and over time, explaining most of the temporal increase in rate of Alzheimer's disease.

View Article: PubMed Central - PubMed

Affiliation: Department of Medicine, College of Medicine, Howard University, 2041 Georgia Ave, Washington, DC 20060, USA. rfg2.howard.edu@gmail.com

ABSTRACT
Geographic and temporal variation in occurrence of dementia within the US has received little attention despite its importance for generation of new etiologic hypotheses and health services research. We examine methodological problems in the use of vital statistics data for assessing variation over time, among states and within states in the US. We analyzed the US multiple cause of death files for 2005-2006 and 1999-2000 US deaths with Alzheimer's Disease (International Classification of Disease 10th revision code G30) and other dementias (codes F01, F02, R54) coded as underlying or contributing cause of death based on the death certificate. Age-adjusted death rates were computed by year, state or county for persons aged 65 years and over. In 2005-2006 combined, 555,904 total deaths occurred with any dementia type (212,386 for Alzheimer's disease) coded as underlying or contributing cause. Among the states, age-adjusted rates per 100,000 per year varied by two fold ranging from 458 in New York to 921 in Oregon. Similar geographic patterns were seen for Alzheimer's disease. However, between 1999-2000 and 2005-2006 the US death rate for all dementia increased only from 559 to 695 (24%) while that for Alzheimer's disease doubled from 135 to 266. Use of specific (G30, F01) versus non-specific diagnoses (F02, R54) varied among states and over time, explaining most of the temporal increase in rate of Alzheimer's disease. Further research is needed to assess artifacts of diagnosis, certification or coding, utilization of health services, versus biological variation as possible causes of temporal and geographic variation to enhance utility of mortality data for dementia monitoring and research.

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Age-adjusted rate of death with diagnosis of Alzheimer’s disease or other dementias by state for persons aged 65 years and over: United States, 2005–2006.
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f1-ijerph-08-01244: Age-adjusted rate of death with diagnosis of Alzheimer’s disease or other dementias by state for persons aged 65 years and over: United States, 2005–2006.

Mentions: Results. Among 555,904 with any dementia diagnosis in 2005–2006, 212,386 deaths occurred with Alzheimer’s disease coded as underlying (142,518) or contributing cause (69,868). Among the states, age-adjusted rates per 100,000 for all dementia varied by two fold ranging from 458 in New York to 921 in Oregon (Table 1). Rates varied by over three fold for Alzheimer’s disease ranging from 133 in New York to 419 in Washington (Supplementary Table 1). Figure 1 shows that high rates (>816 per 100,000) for dementia were seen in the Pacific Northwest, some mountain states, Northern New England, East-south central states and the Carolinas. Rates >300 per 100,000 for Alzheimer’s disease were seen in the Pacific Northwest, Northern New England, East-south central states and the Dakotas (Supplementary Figure 1). Low rates were seen in Southern New England and the Mid-Atlantic, Hawaii, Nevada and Florida for both categories.


Population surveillance of dementia mortality.

Gillum RF, Yorrick R, Obisesan TO - Int J Environ Res Public Health (2011)

Age-adjusted rate of death with diagnosis of Alzheimer’s disease or other dementias by state for persons aged 65 years and over: United States, 2005–2006.
© Copyright Policy - open-access
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC3118887&req=5

f1-ijerph-08-01244: Age-adjusted rate of death with diagnosis of Alzheimer’s disease or other dementias by state for persons aged 65 years and over: United States, 2005–2006.
Mentions: Results. Among 555,904 with any dementia diagnosis in 2005–2006, 212,386 deaths occurred with Alzheimer’s disease coded as underlying (142,518) or contributing cause (69,868). Among the states, age-adjusted rates per 100,000 for all dementia varied by two fold ranging from 458 in New York to 921 in Oregon (Table 1). Rates varied by over three fold for Alzheimer’s disease ranging from 133 in New York to 419 in Washington (Supplementary Table 1). Figure 1 shows that high rates (>816 per 100,000) for dementia were seen in the Pacific Northwest, some mountain states, Northern New England, East-south central states and the Carolinas. Rates >300 per 100,000 for Alzheimer’s disease were seen in the Pacific Northwest, Northern New England, East-south central states and the Dakotas (Supplementary Figure 1). Low rates were seen in Southern New England and the Mid-Atlantic, Hawaii, Nevada and Florida for both categories.

Bottom Line: Among the states, age-adjusted rates per 100,000 per year varied by two fold ranging from 458 in New York to 921 in Oregon.Similar geographic patterns were seen for Alzheimer's disease.Use of specific (G30, F01) versus non-specific diagnoses (F02, R54) varied among states and over time, explaining most of the temporal increase in rate of Alzheimer's disease.

View Article: PubMed Central - PubMed

Affiliation: Department of Medicine, College of Medicine, Howard University, 2041 Georgia Ave, Washington, DC 20060, USA. rfg2.howard.edu@gmail.com

ABSTRACT
Geographic and temporal variation in occurrence of dementia within the US has received little attention despite its importance for generation of new etiologic hypotheses and health services research. We examine methodological problems in the use of vital statistics data for assessing variation over time, among states and within states in the US. We analyzed the US multiple cause of death files for 2005-2006 and 1999-2000 US deaths with Alzheimer's Disease (International Classification of Disease 10th revision code G30) and other dementias (codes F01, F02, R54) coded as underlying or contributing cause of death based on the death certificate. Age-adjusted death rates were computed by year, state or county for persons aged 65 years and over. In 2005-2006 combined, 555,904 total deaths occurred with any dementia type (212,386 for Alzheimer's disease) coded as underlying or contributing cause. Among the states, age-adjusted rates per 100,000 per year varied by two fold ranging from 458 in New York to 921 in Oregon. Similar geographic patterns were seen for Alzheimer's disease. However, between 1999-2000 and 2005-2006 the US death rate for all dementia increased only from 559 to 695 (24%) while that for Alzheimer's disease doubled from 135 to 266. Use of specific (G30, F01) versus non-specific diagnoses (F02, R54) varied among states and over time, explaining most of the temporal increase in rate of Alzheimer's disease. Further research is needed to assess artifacts of diagnosis, certification or coding, utilization of health services, versus biological variation as possible causes of temporal and geographic variation to enhance utility of mortality data for dementia monitoring and research.

Show MeSH
Related in: MedlinePlus