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The public health impact of coccidioidomycosis in Arizona and California.

Hector RF, Rutherford GW, Tsang CA, Erhart LM, McCotter O, Anderson SM, Komatsu K, Tabnak F, Vugia DJ, Yang Y, Galgiani JN - Int J Environ Res Public Health (2011)

Bottom Line: The numbers of reported cases of coccidioidomycosis in Arizona and California have risen dramatically over the past decade, with a 97.8% and 91.1% increase in incidence rates from 2001 to 2006 in the two states, respectively.Of those cases with reported race/ethnicity information, Black/African Americans in Arizona and Hispanics and African/Americans in California experienced a disproportionately higher frequency of disease compared to other racial/ethnic groups.Similarly, the inability of currently available therapeutics to reduce the duration and morbidity of this disease underscores the need for improved therapeutics and a preventive vaccine.

View Article: PubMed Central - PubMed

Affiliation: Global Health Sciences, University of California, San Francisco,1200 Beale St, #1200, San Francisco, CA 94105, USA. rhector@psg.ucsf.edu

ABSTRACT
The numbers of reported cases of coccidioidomycosis in Arizona and California have risen dramatically over the past decade, with a 97.8% and 91.1% increase in incidence rates from 2001 to 2006 in the two states, respectively. Of those cases with reported race/ethnicity information, Black/African Americans in Arizona and Hispanics and African/Americans in California experienced a disproportionately higher frequency of disease compared to other racial/ethnic groups. Lack of early diagnosis continues to be a problem, particularly in suspect community-acquired pneumonia, underscoring the need for more rapid and sensitive tests. Similarly, the inability of currently available therapeutics to reduce the duration and morbidity of this disease underscores the need for improved therapeutics and a preventive vaccine.

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Related in: MedlinePlus

Coccidioidomycosis county-specific incidence rate ranges, California, 2001–2009.
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f9-ijerph-08-01150: Coccidioidomycosis county-specific incidence rate ranges, California, 2001–2009.

Mentions: The counties of Kern (annual average rate: 144/100,000; cumulative cases: 9,998), Kings (annual average rate: 68/100,000; cumulative cases: 900), Tulare (annual average rate: 37/100,000; cumulative cases: 1,374), Fresno (annual average rate: 33/100,000; cumulative cases: 2,635), Madera (annual average rate: 15/100,000; cumulative cases: 196), and San Luis Obispo (annual average rate: 31/100,000; cumulative cases: 734) had the highest annual average incidence rates during the study period. These counties are established as being Coccidioides-endemic areas and their cumulative cases represent 76% of all cases reported during the study period. There were only five out of the 58 counties in California with no reported cases during the entire study period. Figure 9 presents county-specific cumulative incidence ranges per 100,000 population for years 2001–2009 across California. Counties with unreliable rates within the time period were marked with hatched lines.


The public health impact of coccidioidomycosis in Arizona and California.

Hector RF, Rutherford GW, Tsang CA, Erhart LM, McCotter O, Anderson SM, Komatsu K, Tabnak F, Vugia DJ, Yang Y, Galgiani JN - Int J Environ Res Public Health (2011)

Coccidioidomycosis county-specific incidence rate ranges, California, 2001–2009.
© Copyright Policy - open-access
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC3118883&req=5

f9-ijerph-08-01150: Coccidioidomycosis county-specific incidence rate ranges, California, 2001–2009.
Mentions: The counties of Kern (annual average rate: 144/100,000; cumulative cases: 9,998), Kings (annual average rate: 68/100,000; cumulative cases: 900), Tulare (annual average rate: 37/100,000; cumulative cases: 1,374), Fresno (annual average rate: 33/100,000; cumulative cases: 2,635), Madera (annual average rate: 15/100,000; cumulative cases: 196), and San Luis Obispo (annual average rate: 31/100,000; cumulative cases: 734) had the highest annual average incidence rates during the study period. These counties are established as being Coccidioides-endemic areas and their cumulative cases represent 76% of all cases reported during the study period. There were only five out of the 58 counties in California with no reported cases during the entire study period. Figure 9 presents county-specific cumulative incidence ranges per 100,000 population for years 2001–2009 across California. Counties with unreliable rates within the time period were marked with hatched lines.

Bottom Line: The numbers of reported cases of coccidioidomycosis in Arizona and California have risen dramatically over the past decade, with a 97.8% and 91.1% increase in incidence rates from 2001 to 2006 in the two states, respectively.Of those cases with reported race/ethnicity information, Black/African Americans in Arizona and Hispanics and African/Americans in California experienced a disproportionately higher frequency of disease compared to other racial/ethnic groups.Similarly, the inability of currently available therapeutics to reduce the duration and morbidity of this disease underscores the need for improved therapeutics and a preventive vaccine.

View Article: PubMed Central - PubMed

Affiliation: Global Health Sciences, University of California, San Francisco,1200 Beale St, #1200, San Francisco, CA 94105, USA. rhector@psg.ucsf.edu

ABSTRACT
The numbers of reported cases of coccidioidomycosis in Arizona and California have risen dramatically over the past decade, with a 97.8% and 91.1% increase in incidence rates from 2001 to 2006 in the two states, respectively. Of those cases with reported race/ethnicity information, Black/African Americans in Arizona and Hispanics and African/Americans in California experienced a disproportionately higher frequency of disease compared to other racial/ethnic groups. Lack of early diagnosis continues to be a problem, particularly in suspect community-acquired pneumonia, underscoring the need for more rapid and sensitive tests. Similarly, the inability of currently available therapeutics to reduce the duration and morbidity of this disease underscores the need for improved therapeutics and a preventive vaccine.

Show MeSH
Related in: MedlinePlus