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A comparative study on the efficacy of a commercial fibrin adhesive (Tisseel) vis-à-vis silk suture on wound closure following periodontal surgical procedures.

Manimegalai AG - J Indian Soc Periodontol (2010)

Bottom Line: In the experimental groups, the flaps/grafts were approximated with fibrin adhesive sealant (Tisseel(;)).Clinical parameters were taken pre-operatively.operatively and post-operatively on the 1(st), 2(nd), 3(rd), 7(th), and 10(th), day.The Fibrin Adhesive System (FAS) showed superior results in all the parameters measured, i.e., hemostasis, fixation of tissues, reduction in plaque and gingival index and probing depth postoperatively.

View Article: PubMed Central - PubMed

Affiliation: Department of Periodontology & Implantology, Priyadarshini Dental College, Pandur, Thiruvallur District, Tamil Nadu, India.

ABSTRACT

Aims and objectives: To evaluate the efficacy of fibrin adhesive sealant (Tisseel(®)), a human biological tissue adhesive, as compared to conventional suture placement in pocket elimination and mucogingival surgical procedures.

Materials and methods: The study sample consisted of 25 patients (10 male and 15 female patients), in the age group of 25-40 years, with localized periodontitis in relation to the anterior region of the maxilla and mandible. They were divided into three surgical groups: Group I, Group II and Group III. Each of these groups was further divided into control and experimental groups. In all the control groups, the flaps/grafts were approximated with 4-0 black braided silk. In the experimental groups, the flaps/grafts were approximated with fibrin adhesive sealant (Tisseel(;)). Clinical parameters were taken pre-operatively.operatively and post-operatively on the 1(st), 2(nd), 3(rd), 7(th), and 10(th), day.

Results: The Fibrin Adhesive System (FAS) showed superior results in all the parameters measured, i.e., hemostasis, fixation of tissues, reduction in plaque and gingival index and probing depth postoperatively.

Conclusion: The results of this study indicate that periodontal surgery using FAS enhances various periodontal regenerative surgical procedures.

No MeSH data available.


Related in: MedlinePlus

Tisseeling kit
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Figure 1: Tisseeling kit

Mentions: The study sample consisted of 25 patients (10 male and 15 female patients) with localized periodontitis in the anterior region of maxilla and mandible. They were randomly selected and divided into three groups (Group I, Group II and Group III). These groups were further divided into control groups where 4-0 black braided silk was used and experimental groups where adhesive sealant (Tisseel;) was used [Figures 1 and 2].


A comparative study on the efficacy of a commercial fibrin adhesive (Tisseel) vis-à-vis silk suture on wound closure following periodontal surgical procedures.

Manimegalai AG - J Indian Soc Periodontol (2010)

Tisseeling kit
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3118073&req=5

Figure 1: Tisseeling kit
Mentions: The study sample consisted of 25 patients (10 male and 15 female patients) with localized periodontitis in the anterior region of maxilla and mandible. They were randomly selected and divided into three groups (Group I, Group II and Group III). These groups were further divided into control groups where 4-0 black braided silk was used and experimental groups where adhesive sealant (Tisseel;) was used [Figures 1 and 2].

Bottom Line: In the experimental groups, the flaps/grafts were approximated with fibrin adhesive sealant (Tisseel(;)).Clinical parameters were taken pre-operatively.operatively and post-operatively on the 1(st), 2(nd), 3(rd), 7(th), and 10(th), day.The Fibrin Adhesive System (FAS) showed superior results in all the parameters measured, i.e., hemostasis, fixation of tissues, reduction in plaque and gingival index and probing depth postoperatively.

View Article: PubMed Central - PubMed

Affiliation: Department of Periodontology & Implantology, Priyadarshini Dental College, Pandur, Thiruvallur District, Tamil Nadu, India.

ABSTRACT

Aims and objectives: To evaluate the efficacy of fibrin adhesive sealant (Tisseel(®)), a human biological tissue adhesive, as compared to conventional suture placement in pocket elimination and mucogingival surgical procedures.

Materials and methods: The study sample consisted of 25 patients (10 male and 15 female patients), in the age group of 25-40 years, with localized periodontitis in relation to the anterior region of the maxilla and mandible. They were divided into three surgical groups: Group I, Group II and Group III. Each of these groups was further divided into control and experimental groups. In all the control groups, the flaps/grafts were approximated with 4-0 black braided silk. In the experimental groups, the flaps/grafts were approximated with fibrin adhesive sealant (Tisseel(;)). Clinical parameters were taken pre-operatively.operatively and post-operatively on the 1(st), 2(nd), 3(rd), 7(th), and 10(th), day.

Results: The Fibrin Adhesive System (FAS) showed superior results in all the parameters measured, i.e., hemostasis, fixation of tissues, reduction in plaque and gingival index and probing depth postoperatively.

Conclusion: The results of this study indicate that periodontal surgery using FAS enhances various periodontal regenerative surgical procedures.

No MeSH data available.


Related in: MedlinePlus