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Diabetes and periodontitis.

Deshpande K, Jain A, Sharma R, Prashar S, Jain R - J Indian Soc Periodontol (2010)

Bottom Line: What is the effect of periodontal intervention on metabolic control of diabetes?After a thorough survey of literature, it was observed that diabetes acts as a risk factor in development of periodontitis as periodontitis is significantly aggravated in patients suffering from diabetes having long term hyperglycemia.At the same time, patients are needed to be made aware of regular periodontal maintenance schedule and oral hygiene.

View Article: PubMed Central - PubMed

Affiliation: Department of Biochemistry, Dr. HS Judge Institute of Dental Sciences & Hospital, Panjab University, Sector 25, Chandigarh, India.

ABSTRACT
The main aim of this review is to update the reader with practical knowledge concerning the relationship between diabetes mellitus and periodontal diseases. Exclusive data is available on the association between these two chronic diseases till date. Articles published on this relationship often provide the knowledge of definitions of diabetes mellitus and periodontal diseases, prevalence, extent, severity of periodontal disease, complications of diabetes along with the possible underlying mechanisms. The authors reviewed human epidemiological studies, cross-sectional observations and longitudinal cohort, case control that evaluated variables exclusively over the past 30 years and the predominant findings from the "certain" articles are summarized in this review. This review clarifies certain queries such as 1) Do periodontal diseases have an effect on the metabolic control of diabetes? 2) Does diabetes act as a risk factor of periodontitis? 3) What are the possible underlying mechanisms relating the connection between these two chronic diseases? 4) What is the effect of periodontal intervention on metabolic control of diabetes? After a thorough survey of literature, it was observed that diabetes acts as a risk factor in development of periodontitis as periodontitis is significantly aggravated in patients suffering from diabetes having long term hyperglycemia. Different mechanisms underlying the association between the accelerated periodontal disease and diabetes are emerging but still more work is required. Major efforts are required to elucidate the impact of periodontal diseases on diabetes. At the same time, patients are needed to be made aware of regular periodontal maintenance schedule and oral hygiene.

No MeSH data available.


Related in: MedlinePlus

Hypothetical model of association between periodontal disease and diabetes showing the cascade of events contributing to periodontitis in combination with diabetes with and without periodontal therapy
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Related In: Results  -  Collection

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Figure 1: Hypothetical model of association between periodontal disease and diabetes showing the cascade of events contributing to periodontitis in combination with diabetes with and without periodontal therapy

Mentions: Based on this data, we have developed a model to address the relationship between diabetes and periodontal disease [Figure 1]. Various mechanisms mentioned above may contribute individually or synergistically but eventually leads/ lead to periodontits as the complication to diabetes. Although the exact mechanism of action is not fully understood but diabetes, poor oral health habits, heredity, old age, decreased immunity of the host play a leading role as main risk factor. Combination of these factors may contribute to various mechanisms underlying the association between periodontal disease and diabetes including – glucose level changes, subgingival flora components, blood perfusion, host response and metabolism of periodontal tissue.[68]


Diabetes and periodontitis.

Deshpande K, Jain A, Sharma R, Prashar S, Jain R - J Indian Soc Periodontol (2010)

Hypothetical model of association between periodontal disease and diabetes showing the cascade of events contributing to periodontitis in combination with diabetes with and without periodontal therapy
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3118068&req=5

Figure 1: Hypothetical model of association between periodontal disease and diabetes showing the cascade of events contributing to periodontitis in combination with diabetes with and without periodontal therapy
Mentions: Based on this data, we have developed a model to address the relationship between diabetes and periodontal disease [Figure 1]. Various mechanisms mentioned above may contribute individually or synergistically but eventually leads/ lead to periodontits as the complication to diabetes. Although the exact mechanism of action is not fully understood but diabetes, poor oral health habits, heredity, old age, decreased immunity of the host play a leading role as main risk factor. Combination of these factors may contribute to various mechanisms underlying the association between periodontal disease and diabetes including – glucose level changes, subgingival flora components, blood perfusion, host response and metabolism of periodontal tissue.[68]

Bottom Line: What is the effect of periodontal intervention on metabolic control of diabetes?After a thorough survey of literature, it was observed that diabetes acts as a risk factor in development of periodontitis as periodontitis is significantly aggravated in patients suffering from diabetes having long term hyperglycemia.At the same time, patients are needed to be made aware of regular periodontal maintenance schedule and oral hygiene.

View Article: PubMed Central - PubMed

Affiliation: Department of Biochemistry, Dr. HS Judge Institute of Dental Sciences & Hospital, Panjab University, Sector 25, Chandigarh, India.

ABSTRACT
The main aim of this review is to update the reader with practical knowledge concerning the relationship between diabetes mellitus and periodontal diseases. Exclusive data is available on the association between these two chronic diseases till date. Articles published on this relationship often provide the knowledge of definitions of diabetes mellitus and periodontal diseases, prevalence, extent, severity of periodontal disease, complications of diabetes along with the possible underlying mechanisms. The authors reviewed human epidemiological studies, cross-sectional observations and longitudinal cohort, case control that evaluated variables exclusively over the past 30 years and the predominant findings from the "certain" articles are summarized in this review. This review clarifies certain queries such as 1) Do periodontal diseases have an effect on the metabolic control of diabetes? 2) Does diabetes act as a risk factor of periodontitis? 3) What are the possible underlying mechanisms relating the connection between these two chronic diseases? 4) What is the effect of periodontal intervention on metabolic control of diabetes? After a thorough survey of literature, it was observed that diabetes acts as a risk factor in development of periodontitis as periodontitis is significantly aggravated in patients suffering from diabetes having long term hyperglycemia. Different mechanisms underlying the association between the accelerated periodontal disease and diabetes are emerging but still more work is required. Major efforts are required to elucidate the impact of periodontal diseases on diabetes. At the same time, patients are needed to be made aware of regular periodontal maintenance schedule and oral hygiene.

No MeSH data available.


Related in: MedlinePlus