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Uncommon manifestations of Endocervical Malignant Mixed Mullerian Tumor with Incidental Bilateral Fallopian Tube Carcinoma.

Prasad KH, Makannavar JH, Shetty J - J Lab Physicians (2011)

Bottom Line: Histopathology revealed malignant mixed Mullerian tumor.The patient was treated with carboplatin regime and found to be disease-free for 1 year.This case presented because of a rare combination of the lesions.

View Article: PubMed Central - PubMed

Affiliation: Department of Pathology, K S Hegde Medical Academy of Nitte University, Mangalore, Karnataka, India.

ABSTRACT
A 43-year-old perimenopausal lady presented with bleeding per vagina and lower abdominal pain. On evaluation, she had cervical polyp, which expelled spontaneously during the per speculum examination. Histopathology revealed malignant mixed Mullerian tumor. Extended hysterectomy with salphingo oophorectomy was carried out, which showed bilateral fallopian tube carcinoma and leiomyoma uterus. The patient was treated with carboplatin regime and found to be disease-free for 1 year. This case presented because of a rare combination of the lesions.

No MeSH data available.


Related in: MedlinePlus

(a) The endocervical epithelium and stroma showing malignant features (hematoxylin and eosin, ×100), (b) Deeper stroma showing endometrial stromal sarcoma features (hematoxylin and eosin, ×400)
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Figure 1: (a) The endocervical epithelium and stroma showing malignant features (hematoxylin and eosin, ×100), (b) Deeper stroma showing endometrial stromal sarcoma features (hematoxylin and eosin, ×400)

Mentions: The spontaneously expelled grey-brown polyp [Figure 1a] on microscopy showed biphasic tumor cells with the epithelial component arranged in papillary structures and tubules. The stromal component [Figure 1b] showed oval to spindle tumor cells within a myxoid background and numerous proliferating vascular channels. Also, areas of hemorrhage and necrosis were seen. Features were suggestive of MMMT. Curettings from the endometrium and endocervix tissue [Figure 2a] showed papillary carcinoma-endocervix.


Uncommon manifestations of Endocervical Malignant Mixed Mullerian Tumor with Incidental Bilateral Fallopian Tube Carcinoma.

Prasad KH, Makannavar JH, Shetty J - J Lab Physicians (2011)

(a) The endocervical epithelium and stroma showing malignant features (hematoxylin and eosin, ×100), (b) Deeper stroma showing endometrial stromal sarcoma features (hematoxylin and eosin, ×400)
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3118060&req=5

Figure 1: (a) The endocervical epithelium and stroma showing malignant features (hematoxylin and eosin, ×100), (b) Deeper stroma showing endometrial stromal sarcoma features (hematoxylin and eosin, ×400)
Mentions: The spontaneously expelled grey-brown polyp [Figure 1a] on microscopy showed biphasic tumor cells with the epithelial component arranged in papillary structures and tubules. The stromal component [Figure 1b] showed oval to spindle tumor cells within a myxoid background and numerous proliferating vascular channels. Also, areas of hemorrhage and necrosis were seen. Features were suggestive of MMMT. Curettings from the endometrium and endocervix tissue [Figure 2a] showed papillary carcinoma-endocervix.

Bottom Line: Histopathology revealed malignant mixed Mullerian tumor.The patient was treated with carboplatin regime and found to be disease-free for 1 year.This case presented because of a rare combination of the lesions.

View Article: PubMed Central - PubMed

Affiliation: Department of Pathology, K S Hegde Medical Academy of Nitte University, Mangalore, Karnataka, India.

ABSTRACT
A 43-year-old perimenopausal lady presented with bleeding per vagina and lower abdominal pain. On evaluation, she had cervical polyp, which expelled spontaneously during the per speculum examination. Histopathology revealed malignant mixed Mullerian tumor. Extended hysterectomy with salphingo oophorectomy was carried out, which showed bilateral fallopian tube carcinoma and leiomyoma uterus. The patient was treated with carboplatin regime and found to be disease-free for 1 year. This case presented because of a rare combination of the lesions.

No MeSH data available.


Related in: MedlinePlus