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Intra-ocular melanoma metastatic to an axillary lymph node: a case report.

Anne N, Pallapothu R - World J Surg Oncol (2011)

Bottom Line: Case report.There are few reports of regional spread to the maxillofacial bones.Core biopsy will confirm the diagnosis and tailor subsequent management.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of Surgery, Our Lady of Lourdes Memorial Hospital, Binghamton, NY, USA. nirupamaanne@yahoo.com

ABSTRACT

Background: Unusual metastatic presentation of intra-ocular melanoma.

Study design: Case report.

Discussion: Extra-regional lymphatic spread of intra-ocular melanoma has not been reported previously in the literature. The usual pattern of metastasis for intra-ocular melanoma is hematogenous. There are few reports of regional spread to the maxillofacial bones. We report an interesting case of a 51 year old female with prior history of right eye melanoma, now presenting with metastasis to the left axilla, which is an extra-regional nodal basin.

Conclusion: In female patients presenting with an isolated axillary mass, with a negative breast work up and known prior history of melanoma, the differential diagnosis should include possible metastatic melanoma. Core biopsy will confirm the diagnosis and tailor subsequent management.

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Related in: MedlinePlus

Ultrasound image of the irregular mass in the left axilla.
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Figure 1: Ultrasound image of the irregular mass in the left axilla.

Mentions: Physical examination was within normal limits with the exception of the left axilla where there is a 2 cm × 2 cm, freely mobile, non-tender, lymph node. Mammograms from three weeks prior were within normal limits. Ultrasound of the left axilla done a week prior to the evaluation (Figure 1) showed an irregular mass, 2.0 × 1.6 × 2.0 cm in size, hypo-echoic, heterogeneous, with some peripheral blood flow. No edge artifact, no posterior acoustic enhancement or shadowing consistent with BIRADS 4 imaging.


Intra-ocular melanoma metastatic to an axillary lymph node: a case report.

Anne N, Pallapothu R - World J Surg Oncol (2011)

Ultrasound image of the irregular mass in the left axilla.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3117737&req=5

Figure 1: Ultrasound image of the irregular mass in the left axilla.
Mentions: Physical examination was within normal limits with the exception of the left axilla where there is a 2 cm × 2 cm, freely mobile, non-tender, lymph node. Mammograms from three weeks prior were within normal limits. Ultrasound of the left axilla done a week prior to the evaluation (Figure 1) showed an irregular mass, 2.0 × 1.6 × 2.0 cm in size, hypo-echoic, heterogeneous, with some peripheral blood flow. No edge artifact, no posterior acoustic enhancement or shadowing consistent with BIRADS 4 imaging.

Bottom Line: Case report.There are few reports of regional spread to the maxillofacial bones.Core biopsy will confirm the diagnosis and tailor subsequent management.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of Surgery, Our Lady of Lourdes Memorial Hospital, Binghamton, NY, USA. nirupamaanne@yahoo.com

ABSTRACT

Background: Unusual metastatic presentation of intra-ocular melanoma.

Study design: Case report.

Discussion: Extra-regional lymphatic spread of intra-ocular melanoma has not been reported previously in the literature. The usual pattern of metastasis for intra-ocular melanoma is hematogenous. There are few reports of regional spread to the maxillofacial bones. We report an interesting case of a 51 year old female with prior history of right eye melanoma, now presenting with metastasis to the left axilla, which is an extra-regional nodal basin.

Conclusion: In female patients presenting with an isolated axillary mass, with a negative breast work up and known prior history of melanoma, the differential diagnosis should include possible metastatic melanoma. Core biopsy will confirm the diagnosis and tailor subsequent management.

Show MeSH
Related in: MedlinePlus