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Role of imaging in the management of neuro-ophthalmic disorders.

Gandhi RA, Nair AG - Indian J Ophthalmol (2011 Mar-Apr)

Bottom Line: Advancements in physics, computers, and imaging science in the last century have seen neuro-imaging evolving from a plain X-ray to computed tomography, magnetic resonance imaging scans, noninvasive angiography, and special sequences such as fat suppression, fluid attenuation recovery and diffusion-weighted imaging.A prompt prescription of an appropriate imaging modality and the most suitable sequence can increase the diagnostic yield, and in many instances, it can be a sight-saving and even a life-saving decision.This article discusses basic principles of neuro-imaging, its common indications, and the appropriate application in an ophthalmology practice.

View Article: PubMed Central - PubMed

Affiliation: Sankara Nethralaya, A Unit of Medical Research Foundation, Chennai - 600 006, Tamil Nadu, India. rashmin70@yahoo.com

ABSTRACT
Advancements in physics, computers, and imaging science in the last century have seen neuro-imaging evolving from a plain X-ray to computed tomography, magnetic resonance imaging scans, noninvasive angiography, and special sequences such as fat suppression, fluid attenuation recovery and diffusion-weighted imaging. A prompt prescription of an appropriate imaging modality and the most suitable sequence can increase the diagnostic yield, and in many instances, it can be a sight-saving and even a life-saving decision. This article discusses basic principles of neuro-imaging, its common indications, and the appropriate application in an ophthalmology practice.

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Contrast-enhanced axial T1 weighted image with fat suppression shows enhancement and thickening of perineural structures of right optic nerve, suggestive of optic neuritis
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Figure 0004: Contrast-enhanced axial T1 weighted image with fat suppression shows enhancement and thickening of perineural structures of right optic nerve, suggestive of optic neuritis

Mentions: FLAIR (fluid-attenuation inversion recovery) sequences help reveal demyelination or MS plaques in the central nervous system, tumours, and ischemic lesions that often are not visible on routine MRI imaging. Here, as the name suggests, the cerebrospinal fluid (CSF) signal is strongly attenuated, accentuating periventricular and extra-axial disease near the brain surface,[5] thereby allowing visualization of the underlying pathology (e.g., white matter demyelination, posterior reversible encephalopathy) that might otherwise be obscured by the bright signal of normal CSF [Fig. 4].[6]


Role of imaging in the management of neuro-ophthalmic disorders.

Gandhi RA, Nair AG - Indian J Ophthalmol (2011 Mar-Apr)

Contrast-enhanced axial T1 weighted image with fat suppression shows enhancement and thickening of perineural structures of right optic nerve, suggestive of optic neuritis
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3116539&req=5

Figure 0004: Contrast-enhanced axial T1 weighted image with fat suppression shows enhancement and thickening of perineural structures of right optic nerve, suggestive of optic neuritis
Mentions: FLAIR (fluid-attenuation inversion recovery) sequences help reveal demyelination or MS plaques in the central nervous system, tumours, and ischemic lesions that often are not visible on routine MRI imaging. Here, as the name suggests, the cerebrospinal fluid (CSF) signal is strongly attenuated, accentuating periventricular and extra-axial disease near the brain surface,[5] thereby allowing visualization of the underlying pathology (e.g., white matter demyelination, posterior reversible encephalopathy) that might otherwise be obscured by the bright signal of normal CSF [Fig. 4].[6]

Bottom Line: Advancements in physics, computers, and imaging science in the last century have seen neuro-imaging evolving from a plain X-ray to computed tomography, magnetic resonance imaging scans, noninvasive angiography, and special sequences such as fat suppression, fluid attenuation recovery and diffusion-weighted imaging.A prompt prescription of an appropriate imaging modality and the most suitable sequence can increase the diagnostic yield, and in many instances, it can be a sight-saving and even a life-saving decision.This article discusses basic principles of neuro-imaging, its common indications, and the appropriate application in an ophthalmology practice.

View Article: PubMed Central - PubMed

Affiliation: Sankara Nethralaya, A Unit of Medical Research Foundation, Chennai - 600 006, Tamil Nadu, India. rashmin70@yahoo.com

ABSTRACT
Advancements in physics, computers, and imaging science in the last century have seen neuro-imaging evolving from a plain X-ray to computed tomography, magnetic resonance imaging scans, noninvasive angiography, and special sequences such as fat suppression, fluid attenuation recovery and diffusion-weighted imaging. A prompt prescription of an appropriate imaging modality and the most suitable sequence can increase the diagnostic yield, and in many instances, it can be a sight-saving and even a life-saving decision. This article discusses basic principles of neuro-imaging, its common indications, and the appropriate application in an ophthalmology practice.

Show MeSH
Related in: MedlinePlus