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Pharmacological Review on Centella asiatica: A Potential Herbal Cure-all.

Gohil KJ, Patel JA, Gajjar AK - Indian J Pharm Sci (2010)

Bottom Line: In recent times, focus on plant research has increased all over the world.Triterpenoid, saponins, the primary constituents of Centella asiatica are manly believed to be responsible for its wide therapeutic actions.Apart from wound healing, the herb is recommended for the treatment of various skin conditions such as leprosy, lupus, varicose ulcers, eczema, psoriasis, diarrhoea, fever, amenorrhea, diseases of the female genitourinary tract and also for relieving anxiety and improving cognition.

View Article: PubMed Central - PubMed

Affiliation: Department of Pharmacology, Maliba Pharmacy College, Bardoli-394 350, India.

ABSTRACT
In recent times, focus on plant research has increased all over the world. Centella asiatica is an important medicinal herb that is widely used in the orient and is becoming popular in the West. Triterpenoid, saponins, the primary constituents of Centella asiatica are manly believed to be responsible for its wide therapeutic actions. Apart from wound healing, the herb is recommended for the treatment of various skin conditions such as leprosy, lupus, varicose ulcers, eczema, psoriasis, diarrhoea, fever, amenorrhea, diseases of the female genitourinary tract and also for relieving anxiety and improving cognition. The present review attempts to provide comprehensive information on pharmacology, mechanisms of action, various preclinical and clinical studies, safety precautions and current research prospects of the herb. At the same time, studies to evaluate the likelihood of interactions with drugs and herbs on simultaneous use, which is imperative for optimal and safe utilization of the herb, are discussed.

No MeSH data available.


Related in: MedlinePlus

Centella asiatica herb
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Figure 1: Centella asiatica herb

Mentions: Centella asiatica (CA), a clonal, perennial herbaceous creeper belonging to the family Umbellifere (Apiceae) is found throughout India growing in moist places up to an altitude of 1800 m. It is found in most tropical and subtropical countries growing in swampy areas, including parts of India, Pakistan, Sri Lanka, Madagascar, and South Africa and South pacific and Eastern Europe. About 20 species related to CA grow in most parts of the tropic or wet pantropical areas such as rice paddies, and also in rocky, higher elevations[4]. It is a tasteless, odourless plant that thrives in and around water. It has small fan-shaped green leaves with white or light purple-to-pink or white flowers and it bears small oval fruit (fig. 1). The whole plant is used for medicinal purposes[9]. It is widely used as a blood purifier as well as for treating high blood pressure, for memory enhancement and promoting longevity. In Ayurveda, CA is one of the main herbs for revitalizing the nerves and brain cells. Eastern healers relied on CA to treat emotional disorders, such as depression, that were thought to be rooted in physical problems[1011]. In the Western medicine, during the middle of the twentieth century, CA and its alcohol extracts reported to have shown positive results in the treatment of leprosy[12].


Pharmacological Review on Centella asiatica: A Potential Herbal Cure-all.

Gohil KJ, Patel JA, Gajjar AK - Indian J Pharm Sci (2010)

Centella asiatica herb
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3116297&req=5

Figure 1: Centella asiatica herb
Mentions: Centella asiatica (CA), a clonal, perennial herbaceous creeper belonging to the family Umbellifere (Apiceae) is found throughout India growing in moist places up to an altitude of 1800 m. It is found in most tropical and subtropical countries growing in swampy areas, including parts of India, Pakistan, Sri Lanka, Madagascar, and South Africa and South pacific and Eastern Europe. About 20 species related to CA grow in most parts of the tropic or wet pantropical areas such as rice paddies, and also in rocky, higher elevations[4]. It is a tasteless, odourless plant that thrives in and around water. It has small fan-shaped green leaves with white or light purple-to-pink or white flowers and it bears small oval fruit (fig. 1). The whole plant is used for medicinal purposes[9]. It is widely used as a blood purifier as well as for treating high blood pressure, for memory enhancement and promoting longevity. In Ayurveda, CA is one of the main herbs for revitalizing the nerves and brain cells. Eastern healers relied on CA to treat emotional disorders, such as depression, that were thought to be rooted in physical problems[1011]. In the Western medicine, during the middle of the twentieth century, CA and its alcohol extracts reported to have shown positive results in the treatment of leprosy[12].

Bottom Line: In recent times, focus on plant research has increased all over the world.Triterpenoid, saponins, the primary constituents of Centella asiatica are manly believed to be responsible for its wide therapeutic actions.Apart from wound healing, the herb is recommended for the treatment of various skin conditions such as leprosy, lupus, varicose ulcers, eczema, psoriasis, diarrhoea, fever, amenorrhea, diseases of the female genitourinary tract and also for relieving anxiety and improving cognition.

View Article: PubMed Central - PubMed

Affiliation: Department of Pharmacology, Maliba Pharmacy College, Bardoli-394 350, India.

ABSTRACT
In recent times, focus on plant research has increased all over the world. Centella asiatica is an important medicinal herb that is widely used in the orient and is becoming popular in the West. Triterpenoid, saponins, the primary constituents of Centella asiatica are manly believed to be responsible for its wide therapeutic actions. Apart from wound healing, the herb is recommended for the treatment of various skin conditions such as leprosy, lupus, varicose ulcers, eczema, psoriasis, diarrhoea, fever, amenorrhea, diseases of the female genitourinary tract and also for relieving anxiety and improving cognition. The present review attempts to provide comprehensive information on pharmacology, mechanisms of action, various preclinical and clinical studies, safety precautions and current research prospects of the herb. At the same time, studies to evaluate the likelihood of interactions with drugs and herbs on simultaneous use, which is imperative for optimal and safe utilization of the herb, are discussed.

No MeSH data available.


Related in: MedlinePlus