Limits...
Behavior of phenols and phenoxyacids on a bisphenol-A imprinted polymer. Application for selective solid-phase extraction from water and urine samples.

Herrero-Hernández E, Carabias-Martínez R, Rodríguez-Gonzalo E - Int J Mol Sci (2011)

Bottom Line: In an aqueous medium, hydrophobic interactions were found to exert a remarkably non-specific contribution to the overall binding process.Several parameters affecting the extraction efficiency of the BPA-MIP were evaluated to achieve the selective preconcentration of phenols and phenoxyacids from aqueous samples.The possibility of using the BPA-MIP as a selective sorbent to preconcentrate these compounds from other samples such as urine and river water was also explored.

View Article: PubMed Central - PubMed

Affiliation: Institute of Natural Resources and Agrobiology (IRNASA-CSIC), 37008 Salamanca, Spain; E-Mail: eliseo.herrero@irnasa.csic.es.

ABSTRACT
A molecularly imprinted polymer (MIP), obtained by precipitation polymerisation with 4-vinylpyridine as the functional monomer, ethylene glycol dimethacrylate as cross-linker, and bisphenol-A (BPA) as template, was prepared. The binding site configuration of the BPA-MIP was examined using Scatchard analysis. Moreover, the behaviour of the BPA-MIP for the extraction of several phenolic compounds (bisphenol-A, bisphenol-F, 4-nitrophenol, 3-methyl-4-nitrophenol) and phenoxyacid herbicides such as 2,4-D, 2,4,5-T and 2,4,5-TP has been studied in organic and aqueous media in the presence of other pesticides in common use. It was possible to carry out the selective preconcentration of the target analytes from the organic medium with recoveries of higher than 70%. In an aqueous medium, hydrophobic interactions were found to exert a remarkably non-specific contribution to the overall binding process. Several parameters affecting the extraction efficiency of the BPA-MIP were evaluated to achieve the selective preconcentration of phenols and phenoxyacids from aqueous samples. The possibility of using the BPA-MIP as a selective sorbent to preconcentrate these compounds from other samples such as urine and river water was also explored.

Show MeSH
Influence of polymer mass on the recoveries of the fraction eluted from the bisphenol-A-MIP. Sample: 5 mL of toluene with 100 μg L−1 of each compound. Washing and elution steps as in Figure 4.
© Copyright Policy - open-access
Related In: Results  -  Collection

License 1 - License 2
getmorefigures.php?uid=PMC3116193&req=5

f5-ijms-12-03322: Influence of polymer mass on the recoveries of the fraction eluted from the bisphenol-A-MIP. Sample: 5 mL of toluene with 100 μg L−1 of each compound. Washing and elution steps as in Figure 4.

Mentions: The amount of polymer to be used is an important issue to be considered when employing a solid sorbent. To check the influence of this in the recovery values, empty SPE cartridges were filled with different amounts of polymer. For most of the compounds, the recoveries obtained were not significantly better when amounts of sorbent above 100 mg were used. Bearing in mind that the difficulty in passing the sample through the system increases with the increase in polymer mass, we decided to use 100 mg of polymer as a compromise amount (Figure 5).


Behavior of phenols and phenoxyacids on a bisphenol-A imprinted polymer. Application for selective solid-phase extraction from water and urine samples.

Herrero-Hernández E, Carabias-Martínez R, Rodríguez-Gonzalo E - Int J Mol Sci (2011)

Influence of polymer mass on the recoveries of the fraction eluted from the bisphenol-A-MIP. Sample: 5 mL of toluene with 100 μg L−1 of each compound. Washing and elution steps as in Figure 4.
© Copyright Policy - open-access
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC3116193&req=5

f5-ijms-12-03322: Influence of polymer mass on the recoveries of the fraction eluted from the bisphenol-A-MIP. Sample: 5 mL of toluene with 100 μg L−1 of each compound. Washing and elution steps as in Figure 4.
Mentions: The amount of polymer to be used is an important issue to be considered when employing a solid sorbent. To check the influence of this in the recovery values, empty SPE cartridges were filled with different amounts of polymer. For most of the compounds, the recoveries obtained were not significantly better when amounts of sorbent above 100 mg were used. Bearing in mind that the difficulty in passing the sample through the system increases with the increase in polymer mass, we decided to use 100 mg of polymer as a compromise amount (Figure 5).

Bottom Line: In an aqueous medium, hydrophobic interactions were found to exert a remarkably non-specific contribution to the overall binding process.Several parameters affecting the extraction efficiency of the BPA-MIP were evaluated to achieve the selective preconcentration of phenols and phenoxyacids from aqueous samples.The possibility of using the BPA-MIP as a selective sorbent to preconcentrate these compounds from other samples such as urine and river water was also explored.

View Article: PubMed Central - PubMed

Affiliation: Institute of Natural Resources and Agrobiology (IRNASA-CSIC), 37008 Salamanca, Spain; E-Mail: eliseo.herrero@irnasa.csic.es.

ABSTRACT
A molecularly imprinted polymer (MIP), obtained by precipitation polymerisation with 4-vinylpyridine as the functional monomer, ethylene glycol dimethacrylate as cross-linker, and bisphenol-A (BPA) as template, was prepared. The binding site configuration of the BPA-MIP was examined using Scatchard analysis. Moreover, the behaviour of the BPA-MIP for the extraction of several phenolic compounds (bisphenol-A, bisphenol-F, 4-nitrophenol, 3-methyl-4-nitrophenol) and phenoxyacid herbicides such as 2,4-D, 2,4,5-T and 2,4,5-TP has been studied in organic and aqueous media in the presence of other pesticides in common use. It was possible to carry out the selective preconcentration of the target analytes from the organic medium with recoveries of higher than 70%. In an aqueous medium, hydrophobic interactions were found to exert a remarkably non-specific contribution to the overall binding process. Several parameters affecting the extraction efficiency of the BPA-MIP were evaluated to achieve the selective preconcentration of phenols and phenoxyacids from aqueous samples. The possibility of using the BPA-MIP as a selective sorbent to preconcentrate these compounds from other samples such as urine and river water was also explored.

Show MeSH