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Enhancing effect of glycerol on the tensile properties of Bombyx mori cocoon sericin films.

Zhang H, Deng L, Yang M, Min S, Yang L, Zhu L - Int J Mol Sci (2011)

Bottom Line: An environmental physical method described herein was developed to improve the tensile properties of Bombyx mori cocoon sericin films, by using the plasticizer of glycerol, which has a nontoxic effect compared with other chemical crosslinkers.Scanning Electron Microscopy (SEM) observation revealed that glycerol was homogeneously blended with sericin molecules when its content was 10 wt%, while a small amount of redundant glycerol emerged on the surface of sericin films when its content was increased to 20 wt% or higher.Our results suggest that the introduction of glycerol is a novel nontoxic strategy which can improve the mechanical features of sericin-based materials and subsequently promote the feasibility of its application in tissue engineering.

View Article: PubMed Central - PubMed

Affiliation: Institute of Applied Bioresources, College of Animal Sciences, Zhejiang University, Hangzhou 310029, China; E-Mails: hpzhang@zju.edu.cn (H.Z.); denglianxia2008@163.com (L.D.); yangm@zju.edu.cn (M.Y.); minsj@zju.edu.cn (S.M.); yanglei164@163.com (L.Y.).

ABSTRACT
An environmental physical method described herein was developed to improve the tensile properties of Bombyx mori cocoon sericin films, by using the plasticizer of glycerol, which has a nontoxic effect compared with other chemical crosslinkers. The changes in the tensile characteristics and the structure of glycerolated (0-40 wt% of glycerol) sericin films were investigated. Sericin films, both in dry and wet states, showed enhanced tensile properties, which might be regulated by the addition of different concentrations of glycerol. The introduction of glycerol results in the higher amorphous structure in sericin films as evidenced by analysis of attenuated total reflection Fourier transform infrared (ATR-FTIR) spectra, thermogravimetry (TGA) and differential scanning calorimetry (DSC) curves. Scanning Electron Microscopy (SEM) observation revealed that glycerol was homogeneously blended with sericin molecules when its content was 10 wt%, while a small amount of redundant glycerol emerged on the surface of sericin films when its content was increased to 20 wt% or higher. Our results suggest that the introduction of glycerol is a novel nontoxic strategy which can improve the mechanical features of sericin-based materials and subsequently promote the feasibility of its application in tissue engineering.

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TGA thermographs of various sericin films: (A) sericin film; (B) sericin film with 10 wt% glycerol; (C) sericin film with 20 wt% glycerol.
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f4-ijms-12-03170: TGA thermographs of various sericin films: (A) sericin film; (B) sericin film with 10 wt% glycerol; (C) sericin film with 20 wt% glycerol.

Mentions: To further investigate the effect of glycerol on the sericin films structure, the thermal behaviors of sericin films with and without glycerol were determined by TGA and DSC analysis. Figure 4 shows TGA thermographs of sericin films before and after adding the glycerol, which describe the thermal decomposition characteristics of these films. These results indicated that sericin films with glycerol decomposed more quickly than those without glycerol. In addition, sericin films with 20 wt% glycerol decomposed more quickly compared with those with 10 wt% glycerol, suggesting that glycerol can accelerate the decomposition of sericin films.


Enhancing effect of glycerol on the tensile properties of Bombyx mori cocoon sericin films.

Zhang H, Deng L, Yang M, Min S, Yang L, Zhu L - Int J Mol Sci (2011)

TGA thermographs of various sericin films: (A) sericin film; (B) sericin film with 10 wt% glycerol; (C) sericin film with 20 wt% glycerol.
© Copyright Policy - open-access
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC3116183&req=5

f4-ijms-12-03170: TGA thermographs of various sericin films: (A) sericin film; (B) sericin film with 10 wt% glycerol; (C) sericin film with 20 wt% glycerol.
Mentions: To further investigate the effect of glycerol on the sericin films structure, the thermal behaviors of sericin films with and without glycerol were determined by TGA and DSC analysis. Figure 4 shows TGA thermographs of sericin films before and after adding the glycerol, which describe the thermal decomposition characteristics of these films. These results indicated that sericin films with glycerol decomposed more quickly than those without glycerol. In addition, sericin films with 20 wt% glycerol decomposed more quickly compared with those with 10 wt% glycerol, suggesting that glycerol can accelerate the decomposition of sericin films.

Bottom Line: An environmental physical method described herein was developed to improve the tensile properties of Bombyx mori cocoon sericin films, by using the plasticizer of glycerol, which has a nontoxic effect compared with other chemical crosslinkers.Scanning Electron Microscopy (SEM) observation revealed that glycerol was homogeneously blended with sericin molecules when its content was 10 wt%, while a small amount of redundant glycerol emerged on the surface of sericin films when its content was increased to 20 wt% or higher.Our results suggest that the introduction of glycerol is a novel nontoxic strategy which can improve the mechanical features of sericin-based materials and subsequently promote the feasibility of its application in tissue engineering.

View Article: PubMed Central - PubMed

Affiliation: Institute of Applied Bioresources, College of Animal Sciences, Zhejiang University, Hangzhou 310029, China; E-Mails: hpzhang@zju.edu.cn (H.Z.); denglianxia2008@163.com (L.D.); yangm@zju.edu.cn (M.Y.); minsj@zju.edu.cn (S.M.); yanglei164@163.com (L.Y.).

ABSTRACT
An environmental physical method described herein was developed to improve the tensile properties of Bombyx mori cocoon sericin films, by using the plasticizer of glycerol, which has a nontoxic effect compared with other chemical crosslinkers. The changes in the tensile characteristics and the structure of glycerolated (0-40 wt% of glycerol) sericin films were investigated. Sericin films, both in dry and wet states, showed enhanced tensile properties, which might be regulated by the addition of different concentrations of glycerol. The introduction of glycerol results in the higher amorphous structure in sericin films as evidenced by analysis of attenuated total reflection Fourier transform infrared (ATR-FTIR) spectra, thermogravimetry (TGA) and differential scanning calorimetry (DSC) curves. Scanning Electron Microscopy (SEM) observation revealed that glycerol was homogeneously blended with sericin molecules when its content was 10 wt%, while a small amount of redundant glycerol emerged on the surface of sericin films when its content was increased to 20 wt% or higher. Our results suggest that the introduction of glycerol is a novel nontoxic strategy which can improve the mechanical features of sericin-based materials and subsequently promote the feasibility of its application in tissue engineering.

Show MeSH