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Prevalence of modifiable cardiovascular risk factors in long-term renal transplant patients.

Vivek V, Bhandari S - Int J Nephrol Renovasc Dis (2010)

Bottom Line: Multivariable analysis was performed on those factors found to achieve a P value of less than 0.20 after univariate analysis to test for significance in relation to cardiovascular risk as the primary factor.Univariate analysis revealed diabetes and age, and subsequent multivariable analysis revealed age only, as being significantly associated with cardiovascular outcomes.Age is an important determinant of cardiovascular risk.

View Article: PubMed Central - PubMed

Affiliation: Department of Renal Medicine, Hull and East Yorkshire Hospitals NHS Trust and Hull York Medical School, East Yorkshire, UK.

No MeSH data available.


Related in: MedlinePlus

Lipid profiles in transplant patients with (NODAT) and without (ND) in the presence of new onset diabetes after transplantation.Abbreviations: LDL, low-density lipoprotein; HDL, high-density lipoprotein; ND, nondiabetic; NODAT, new onset diabetes after transplantation.
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f2-ijnrd-3-175: Lipid profiles in transplant patients with (NODAT) and without (ND) in the presence of new onset diabetes after transplantation.Abbreviations: LDL, low-density lipoprotein; HDL, high-density lipoprotein; ND, nondiabetic; NODAT, new onset diabetes after transplantation.

Mentions: HMG-CoA reductase inhibitor (statin) therapy was used in 54% of patients. LDL cholesterol levels were lower in the NODAT group (2.3 ± 0.74 mmol/L versus 2.7 ± 0.77 mmol/L, respectively, P = 0.039). Forty-six percent of patients had total cholesterol levels >5 mmol/L (12 NODAT and 46 ND), and 34% had low-density lipoprotein (LDL) cholesterol levels greater than 3 mmol/L (35 ND and 8 NODAT) despite lipid-lowering therapy. High-density lipoprotein (HDL) cholesterol concentrations were lower in NODAT patients. The median total cholesterol:HDL ratio was 3.3 (range 1.53–6.8), with 11% of patients having ratios >5. Triglyceride levels were markedly elevated in patients with NODAT (Figure 2).


Prevalence of modifiable cardiovascular risk factors in long-term renal transplant patients.

Vivek V, Bhandari S - Int J Nephrol Renovasc Dis (2010)

Lipid profiles in transplant patients with (NODAT) and without (ND) in the presence of new onset diabetes after transplantation.Abbreviations: LDL, low-density lipoprotein; HDL, high-density lipoprotein; ND, nondiabetic; NODAT, new onset diabetes after transplantation.
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC3108770&req=5

f2-ijnrd-3-175: Lipid profiles in transplant patients with (NODAT) and without (ND) in the presence of new onset diabetes after transplantation.Abbreviations: LDL, low-density lipoprotein; HDL, high-density lipoprotein; ND, nondiabetic; NODAT, new onset diabetes after transplantation.
Mentions: HMG-CoA reductase inhibitor (statin) therapy was used in 54% of patients. LDL cholesterol levels were lower in the NODAT group (2.3 ± 0.74 mmol/L versus 2.7 ± 0.77 mmol/L, respectively, P = 0.039). Forty-six percent of patients had total cholesterol levels >5 mmol/L (12 NODAT and 46 ND), and 34% had low-density lipoprotein (LDL) cholesterol levels greater than 3 mmol/L (35 ND and 8 NODAT) despite lipid-lowering therapy. High-density lipoprotein (HDL) cholesterol concentrations were lower in NODAT patients. The median total cholesterol:HDL ratio was 3.3 (range 1.53–6.8), with 11% of patients having ratios >5. Triglyceride levels were markedly elevated in patients with NODAT (Figure 2).

Bottom Line: Multivariable analysis was performed on those factors found to achieve a P value of less than 0.20 after univariate analysis to test for significance in relation to cardiovascular risk as the primary factor.Univariate analysis revealed diabetes and age, and subsequent multivariable analysis revealed age only, as being significantly associated with cardiovascular outcomes.Age is an important determinant of cardiovascular risk.

View Article: PubMed Central - PubMed

Affiliation: Department of Renal Medicine, Hull and East Yorkshire Hospitals NHS Trust and Hull York Medical School, East Yorkshire, UK.

No MeSH data available.


Related in: MedlinePlus