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Complete response of a metastatic gastroesophageal adenocarcinoma on irinotecan-based chemotherapy in a dialysis patient.

Verwimp J, Geurs F, Ponette S, Ponette J, Martens J, Bulté K - Int J Nephrol Renovasc Dis (2010)

Bottom Line: An elderly dialysis patient presented with diffuse liver metastases by a gastroesophageal adenocarcinoma.He received combination chemotherapy with 5 fluorouracil and irinotecan.After six months of chemotherapy, liver scans show complete remission.

View Article: PubMed Central - PubMed

Affiliation: Department of Medical Oncology, Regionaal Ziekenhuis Sint-Maria, Ziekenhuislaan, Halle, Belgium.

No MeSH data available.


Related in: MedlinePlus

A) Initial situation with massive liver metastases in left, right, and caudate lobe of the liver. B) Complete response of diffuse liver metastases after four months of irinotecan-based chemotherapy.
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f1-ijnrd-3-061: A) Initial situation with massive liver metastases in left, right, and caudate lobe of the liver. B) Complete response of diffuse liver metastases after four months of irinotecan-based chemotherapy.

Mentions: Six months after starting chemotherapy the CT scan of the liver showed a complete response of the numerous metastases. (Figures 1 and 2) Endoscopy showed only minimal tumor remnants. Marker studies showed a remarkable drop in CA 19.9. (Table 1) Nine months after initiation of treatment, however, the liver metastasis and tumor marker were progressive again. Second line chemotherapy with paclitaxel was started. Doses of chemotherapy were based on a number of case reports on paclitaxel for ovarian cancer in dialysis patients.14,15 CT scan after two months showed further progressive disease. The patient died in hospice 13 months after initial start of chemotherapy.


Complete response of a metastatic gastroesophageal adenocarcinoma on irinotecan-based chemotherapy in a dialysis patient.

Verwimp J, Geurs F, Ponette S, Ponette J, Martens J, Bulté K - Int J Nephrol Renovasc Dis (2010)

A) Initial situation with massive liver metastases in left, right, and caudate lobe of the liver. B) Complete response of diffuse liver metastases after four months of irinotecan-based chemotherapy.
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC3108765&req=5

f1-ijnrd-3-061: A) Initial situation with massive liver metastases in left, right, and caudate lobe of the liver. B) Complete response of diffuse liver metastases after four months of irinotecan-based chemotherapy.
Mentions: Six months after starting chemotherapy the CT scan of the liver showed a complete response of the numerous metastases. (Figures 1 and 2) Endoscopy showed only minimal tumor remnants. Marker studies showed a remarkable drop in CA 19.9. (Table 1) Nine months after initiation of treatment, however, the liver metastasis and tumor marker were progressive again. Second line chemotherapy with paclitaxel was started. Doses of chemotherapy were based on a number of case reports on paclitaxel for ovarian cancer in dialysis patients.14,15 CT scan after two months showed further progressive disease. The patient died in hospice 13 months after initial start of chemotherapy.

Bottom Line: An elderly dialysis patient presented with diffuse liver metastases by a gastroesophageal adenocarcinoma.He received combination chemotherapy with 5 fluorouracil and irinotecan.After six months of chemotherapy, liver scans show complete remission.

View Article: PubMed Central - PubMed

Affiliation: Department of Medical Oncology, Regionaal Ziekenhuis Sint-Maria, Ziekenhuislaan, Halle, Belgium.

No MeSH data available.


Related in: MedlinePlus