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Management of glucocorticoid-induced osteoporosis: prevalence, and emerging treatment options.

Payer J, Brazdilova K, Jackuliak P - Drug Healthc Patient Saf (2010)

Bottom Line: An excess amount of glucocorticoids represents the primary and most frequent etiological factor influencing secondary osteoporosis.Patients receiving glucocorticoids, but also those with the endogenous form of hypercorticism, are at high risk for the loss of bone density, with the subsequent occurrence of pathological fractures.We also include a proposal for both a prophylactic and therapeutic approach that takes into account the risk factors typical for long-term users of glucocorticoids.

View Article: PubMed Central - PubMed

Affiliation: 5th Department of Internal Medicine, Medical Faculty of Comenius University and Faculty Hospital Bratislava, Bratislava, Slovakia.

ABSTRACT
An excess amount of glucocorticoids represents the primary and most frequent etiological factor influencing secondary osteoporosis. Patients receiving glucocorticoids, but also those with the endogenous form of hypercorticism, are at high risk for the loss of bone density, with the subsequent occurrence of pathological fractures. In this review, we summarize the currently available methods of prevention and the treatment of glucocorticoid-induced osteoporosis. We also include a proposal for both a prophylactic and therapeutic approach that takes into account the risk factors typical for long-term users of glucocorticoids.

No MeSH data available.


Related in: MedlinePlus

Effects of glucocorticoids on bone. Derived from.20,85Abbreviations: TST, testosterone; LH, luteinizing hormone; FSH, follicle-stimulating hormone; GI, gastrointestinal; Ca, calcium.
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f1-dhps-2-049: Effects of glucocorticoids on bone. Derived from.20,85Abbreviations: TST, testosterone; LH, luteinizing hormone; FSH, follicle-stimulating hormone; GI, gastrointestinal; Ca, calcium.


Management of glucocorticoid-induced osteoporosis: prevalence, and emerging treatment options.

Payer J, Brazdilova K, Jackuliak P - Drug Healthc Patient Saf (2010)

Effects of glucocorticoids on bone. Derived from.20,85Abbreviations: TST, testosterone; LH, luteinizing hormone; FSH, follicle-stimulating hormone; GI, gastrointestinal; Ca, calcium.
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC3108700&req=5

f1-dhps-2-049: Effects of glucocorticoids on bone. Derived from.20,85Abbreviations: TST, testosterone; LH, luteinizing hormone; FSH, follicle-stimulating hormone; GI, gastrointestinal; Ca, calcium.
Bottom Line: An excess amount of glucocorticoids represents the primary and most frequent etiological factor influencing secondary osteoporosis.Patients receiving glucocorticoids, but also those with the endogenous form of hypercorticism, are at high risk for the loss of bone density, with the subsequent occurrence of pathological fractures.We also include a proposal for both a prophylactic and therapeutic approach that takes into account the risk factors typical for long-term users of glucocorticoids.

View Article: PubMed Central - PubMed

Affiliation: 5th Department of Internal Medicine, Medical Faculty of Comenius University and Faculty Hospital Bratislava, Bratislava, Slovakia.

ABSTRACT
An excess amount of glucocorticoids represents the primary and most frequent etiological factor influencing secondary osteoporosis. Patients receiving glucocorticoids, but also those with the endogenous form of hypercorticism, are at high risk for the loss of bone density, with the subsequent occurrence of pathological fractures. In this review, we summarize the currently available methods of prevention and the treatment of glucocorticoid-induced osteoporosis. We also include a proposal for both a prophylactic and therapeutic approach that takes into account the risk factors typical for long-term users of glucocorticoids.

No MeSH data available.


Related in: MedlinePlus