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Retrospective analysis of endoscopic injection sclerotherapy for rectal varices compared with band ligation.

Sato T, Yamazaki K, Akaike J, Toyota J, Karino Y, Ohmura T - Clin Exp Gastroenterol (2010)

Bottom Line: The clinical outcomes, including complications, related to EIS or EBL retrospectively.In 25 of the 34 patients, EIS was performed weekly 2-5 times (mean, 2.7), and the total amount of sclerosant ranged from 3.2 to 12.0 mL (mean, 5.2 mL).All four patients with recurrence of bleeding were EBL cases, versus no EIS cases (P < 0.05).

View Article: PubMed Central - PubMed

Affiliation: Department of Gastroenterology, Sapporo Kosei General Hospital, Sapporo, Japan.

ABSTRACT

Background and aims: The study's aim was to evaluate the efficacy of endoscopic injection sclerotherapy (EIS) compared with endoscopic band ligation (EBL) in treating rectal varices.

Methods: Data from 34 consecutive patients who underwent endoscopic treatments for rectal varices were analyzed. The clinical outcomes, including complications, related to EIS or EBL retrospectively.

Results: In 25 of the 34 patients, EIS was performed weekly 2-5 times (mean, 2.7), and the total amount of sclerosant ranged from 3.2 to 12.0 mL (mean, 5.2 mL). After EIS, colonoscopy revealed shrinkage of the rectal varices in all 25 patients, with no complications reported. In 9 of the 34 patients, EBL was performed weekly 1-3 times (mean, 2.2), and bands were placed on the varices at 2-12 sites (mean, 8.0). After EBL, colonoscopy revealed ulcers and shrinkage of the rectal varices in all nine patients, eight of whom experienced no operative complications. The overall recurrence rate for rectal varices was 10 of 24 (41.7%), including 5 of 9 (55.6%) receiving EBL and 5 of 15 (33.3%) receiving EIS, over a 1-year follow-up period (n = 24). All four patients with recurrence of bleeding were EBL cases, versus no EIS cases (P < 0.05).

Conclusion: EIS appears superior to EBL with regard to effectiveness and complications after endoscopic treatment of rectal varices.

No MeSH data available.


Related in: MedlinePlus

Recurrence with bleeding-free survival rate was calculated by the Kaplan–Meier method for between-group comparisons.
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f4-ceg-3-159: Recurrence with bleeding-free survival rate was calculated by the Kaplan–Meier method for between-group comparisons.

Mentions: The overall rate of recurrence of rectal varices over the 1-year follow-up period (n = 24) after treatments was 10 of 24 patients (41.7%), including 5 of 9 patients (55.6%) receiving EBL and 5 of 15 patients (33.3%) receiving EIS. The recurrence rate showed no statistically significant difference between the EIS group and the EBL group. The recurrence rate with bleeding was 4 of 10 patients with recurrent rectal varices (40.0%), including 4 of the 5 patients (80.0%) receiving EBL but none of the 5 patients (0%) receiving EIS. The recurrence rate with bleeding in the EBL group was significantly higher than that in the EIS group (P < 0.05) (Figure 4). After the treatments for rectal varices, there was no episode of esophagogastric variceal bleeding in all these cases.


Retrospective analysis of endoscopic injection sclerotherapy for rectal varices compared with band ligation.

Sato T, Yamazaki K, Akaike J, Toyota J, Karino Y, Ohmura T - Clin Exp Gastroenterol (2010)

Recurrence with bleeding-free survival rate was calculated by the Kaplan–Meier method for between-group comparisons.
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC3108668&req=5

f4-ceg-3-159: Recurrence with bleeding-free survival rate was calculated by the Kaplan–Meier method for between-group comparisons.
Mentions: The overall rate of recurrence of rectal varices over the 1-year follow-up period (n = 24) after treatments was 10 of 24 patients (41.7%), including 5 of 9 patients (55.6%) receiving EBL and 5 of 15 patients (33.3%) receiving EIS. The recurrence rate showed no statistically significant difference between the EIS group and the EBL group. The recurrence rate with bleeding was 4 of 10 patients with recurrent rectal varices (40.0%), including 4 of the 5 patients (80.0%) receiving EBL but none of the 5 patients (0%) receiving EIS. The recurrence rate with bleeding in the EBL group was significantly higher than that in the EIS group (P < 0.05) (Figure 4). After the treatments for rectal varices, there was no episode of esophagogastric variceal bleeding in all these cases.

Bottom Line: The clinical outcomes, including complications, related to EIS or EBL retrospectively.In 25 of the 34 patients, EIS was performed weekly 2-5 times (mean, 2.7), and the total amount of sclerosant ranged from 3.2 to 12.0 mL (mean, 5.2 mL).All four patients with recurrence of bleeding were EBL cases, versus no EIS cases (P < 0.05).

View Article: PubMed Central - PubMed

Affiliation: Department of Gastroenterology, Sapporo Kosei General Hospital, Sapporo, Japan.

ABSTRACT

Background and aims: The study's aim was to evaluate the efficacy of endoscopic injection sclerotherapy (EIS) compared with endoscopic band ligation (EBL) in treating rectal varices.

Methods: Data from 34 consecutive patients who underwent endoscopic treatments for rectal varices were analyzed. The clinical outcomes, including complications, related to EIS or EBL retrospectively.

Results: In 25 of the 34 patients, EIS was performed weekly 2-5 times (mean, 2.7), and the total amount of sclerosant ranged from 3.2 to 12.0 mL (mean, 5.2 mL). After EIS, colonoscopy revealed shrinkage of the rectal varices in all 25 patients, with no complications reported. In 9 of the 34 patients, EBL was performed weekly 1-3 times (mean, 2.2), and bands were placed on the varices at 2-12 sites (mean, 8.0). After EBL, colonoscopy revealed ulcers and shrinkage of the rectal varices in all nine patients, eight of whom experienced no operative complications. The overall recurrence rate for rectal varices was 10 of 24 (41.7%), including 5 of 9 (55.6%) receiving EBL and 5 of 15 (33.3%) receiving EIS, over a 1-year follow-up period (n = 24). All four patients with recurrence of bleeding were EBL cases, versus no EIS cases (P < 0.05).

Conclusion: EIS appears superior to EBL with regard to effectiveness and complications after endoscopic treatment of rectal varices.

No MeSH data available.


Related in: MedlinePlus