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Leishmaniasis of the lip diagnosed by lymph node aspiration and treated with a combination of oral ketaconazole and intralesional sodium stibogluconate.

Vasudevan B, Bahal A - Indian J Dermatol (2011)

Bottom Line: Skin smear and biopsy from the lesion did not yield the diagnosis.Needle aspiration from the draining lymph node revealed the diagnostic Leishman-Donovan bodies.The patient responded to treatment with a combination of oral ketoconazole and intralesional sodium stibogluconate.

View Article: PubMed Central - PubMed

Affiliation: Department of Dermatology, MH Shillong, Meghalaya- 793001, India.

ABSTRACT
A 26-year-old male who presented to the dermatology OPD with complaints of a swelling on his lip of 6 months' duration was on examination found to have a solitary ulcerated nodule over the lip and an enlarged submental lymph node. Skin smear and biopsy from the lesion did not yield the diagnosis. Needle aspiration from the draining lymph node revealed the diagnostic Leishman-Donovan bodies. The patient responded to treatment with a combination of oral ketoconazole and intralesional sodium stibogluconate. We report this case because of both the unusual location of the lesion and the unusual method of diagnosis and treatment.

No MeSH data available.


Related in: MedlinePlus

Post treatment photographs
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Figure 4: Post treatment photographs

Mentions: We treated the patient with intralesional sodium stibogluconate once a week for 4 weeks and tablet ketoconazole 400 mg once daily for the same duration. Two weeks after the start of treatment, the lesion had dried up and had started regressing in size [Figure 4]. The lesion completely regressed, without any residual scarring or pigmentation, over 4 weeks. The patient has now been followed up for 1 year and shows no signs of relapse.


Leishmaniasis of the lip diagnosed by lymph node aspiration and treated with a combination of oral ketaconazole and intralesional sodium stibogluconate.

Vasudevan B, Bahal A - Indian J Dermatol (2011)

Post treatment photographs
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3108527&req=5

Figure 4: Post treatment photographs
Mentions: We treated the patient with intralesional sodium stibogluconate once a week for 4 weeks and tablet ketoconazole 400 mg once daily for the same duration. Two weeks after the start of treatment, the lesion had dried up and had started regressing in size [Figure 4]. The lesion completely regressed, without any residual scarring or pigmentation, over 4 weeks. The patient has now been followed up for 1 year and shows no signs of relapse.

Bottom Line: Skin smear and biopsy from the lesion did not yield the diagnosis.Needle aspiration from the draining lymph node revealed the diagnostic Leishman-Donovan bodies.The patient responded to treatment with a combination of oral ketoconazole and intralesional sodium stibogluconate.

View Article: PubMed Central - PubMed

Affiliation: Department of Dermatology, MH Shillong, Meghalaya- 793001, India.

ABSTRACT
A 26-year-old male who presented to the dermatology OPD with complaints of a swelling on his lip of 6 months' duration was on examination found to have a solitary ulcerated nodule over the lip and an enlarged submental lymph node. Skin smear and biopsy from the lesion did not yield the diagnosis. Needle aspiration from the draining lymph node revealed the diagnostic Leishman-Donovan bodies. The patient responded to treatment with a combination of oral ketoconazole and intralesional sodium stibogluconate. We report this case because of both the unusual location of the lesion and the unusual method of diagnosis and treatment.

No MeSH data available.


Related in: MedlinePlus