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Leishmaniasis of the lip diagnosed by lymph node aspiration and treated with a combination of oral ketaconazole and intralesional sodium stibogluconate.

Vasudevan B, Bahal A - Indian J Dermatol (2011)

Bottom Line: Skin smear and biopsy from the lesion did not yield the diagnosis.Needle aspiration from the draining lymph node revealed the diagnostic Leishman-Donovan bodies.The patient responded to treatment with a combination of oral ketoconazole and intralesional sodium stibogluconate.

View Article: PubMed Central - PubMed

Affiliation: Department of Dermatology, MH Shillong, Meghalaya- 793001, India.

ABSTRACT
A 26-year-old male who presented to the dermatology OPD with complaints of a swelling on his lip of 6 months' duration was on examination found to have a solitary ulcerated nodule over the lip and an enlarged submental lymph node. Skin smear and biopsy from the lesion did not yield the diagnosis. Needle aspiration from the draining lymph node revealed the diagnostic Leishman-Donovan bodies. The patient responded to treatment with a combination of oral ketoconazole and intralesional sodium stibogluconate. We report this case because of both the unusual location of the lesion and the unusual method of diagnosis and treatment.

No MeSH data available.


Related in: MedlinePlus

Ulcerated nodule on the upper lip
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Figure 1: Ulcerated nodule on the upper lip

Mentions: On examination, the vital parameters were normal. There was no hepatosplenomegaly. All other systems were also normal. Local examination of the face revealed a 4 × 3 cm nodular, indurated, swelling with well-defined edges over the upper lip and extending into the labial mucosa [Figure 1]. The center of the nodule was ulcerated and tender, with overlying crusting and pus discharge. There was a solitary 1 × 1 cm enlarged, nontender, submental lymph node on the left side. A clinical diagnosis of cutaneous leishmaniasis was made, with insect bite reaction and cutaneous tuberculosis kept in mind as remote possibilities.


Leishmaniasis of the lip diagnosed by lymph node aspiration and treated with a combination of oral ketaconazole and intralesional sodium stibogluconate.

Vasudevan B, Bahal A - Indian J Dermatol (2011)

Ulcerated nodule on the upper lip
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3108527&req=5

Figure 1: Ulcerated nodule on the upper lip
Mentions: On examination, the vital parameters were normal. There was no hepatosplenomegaly. All other systems were also normal. Local examination of the face revealed a 4 × 3 cm nodular, indurated, swelling with well-defined edges over the upper lip and extending into the labial mucosa [Figure 1]. The center of the nodule was ulcerated and tender, with overlying crusting and pus discharge. There was a solitary 1 × 1 cm enlarged, nontender, submental lymph node on the left side. A clinical diagnosis of cutaneous leishmaniasis was made, with insect bite reaction and cutaneous tuberculosis kept in mind as remote possibilities.

Bottom Line: Skin smear and biopsy from the lesion did not yield the diagnosis.Needle aspiration from the draining lymph node revealed the diagnostic Leishman-Donovan bodies.The patient responded to treatment with a combination of oral ketoconazole and intralesional sodium stibogluconate.

View Article: PubMed Central - PubMed

Affiliation: Department of Dermatology, MH Shillong, Meghalaya- 793001, India.

ABSTRACT
A 26-year-old male who presented to the dermatology OPD with complaints of a swelling on his lip of 6 months' duration was on examination found to have a solitary ulcerated nodule over the lip and an enlarged submental lymph node. Skin smear and biopsy from the lesion did not yield the diagnosis. Needle aspiration from the draining lymph node revealed the diagnostic Leishman-Donovan bodies. The patient responded to treatment with a combination of oral ketoconazole and intralesional sodium stibogluconate. We report this case because of both the unusual location of the lesion and the unusual method of diagnosis and treatment.

No MeSH data available.


Related in: MedlinePlus