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Imaging of the Head and Neck following Radiation Treatment.

Debnam JM - Patholog Res Int (2011)

Bottom Line: Squamous cell carcinoma of the head and neck occurs in approximately 40,000 patients annually in the United States and is often treated with radiation therapy.Radiological studies are obtained following treatment for head and neck malignancies to assess for recurrent tumor, posttreatment changes, and associated complications.As post-treatment imaging studies are often discussed at radiology/pathology working conferences, knowledge of the imaging appearance of radiation-associated changes in the head and neck and the terminology used by neuroradiologists may not only aid in interpretation of the pathologic specimen, but also assist in communications with neuroradiologists and referring clinicians.

View Article: PubMed Central - PubMed

Affiliation: Section of Neuroradiology, Department of Radiology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.

ABSTRACT
Squamous cell carcinoma of the head and neck occurs in approximately 40,000 patients annually in the United States and is often treated with radiation therapy. Radiological studies are obtained following treatment for head and neck malignancies to assess for recurrent tumor, posttreatment changes, and associated complications. Radiation treatment creates a difficult clinical picture for oncologists, head and neck surgeons, neuroradiologists, and neuropathologists. As post-treatment imaging studies are often discussed at radiology/pathology working conferences, knowledge of the imaging appearance of radiation-associated changes in the head and neck and the terminology used by neuroradiologists may not only aid in interpretation of the pathologic specimen, but also assist in communications with neuroradiologists and referring clinicians.

No MeSH data available.


Related in: MedlinePlus

Benign and malignant soft tissue ulceration: (a) Axial contrast-enhanced CT of the oral cavity (soft tissue window) shows a benign ulceration (arrow) without an associated soft tissue mass. (b) Axial contrast-enhanced CT (soft tissue window) shows recurrent tumor characterized by irregular enhancement along the floor of the ulceration (arrows).
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fig6: Benign and malignant soft tissue ulceration: (a) Axial contrast-enhanced CT of the oral cavity (soft tissue window) shows a benign ulceration (arrow) without an associated soft tissue mass. (b) Axial contrast-enhanced CT (soft tissue window) shows recurrent tumor characterized by irregular enhancement along the floor of the ulceration (arrows).

Mentions: Ulceration is defined as a defect, or excavation, of the surface of a tissue or organ, which is produced by the sloughing of inflammatory necrotic tissue [26]. As most necrosis and many recurrences occur within 2 years following radiation therapy [26] and the risk of injury related to radiation necrosis is greatest during the first 6–12 months after radiation therapy [21, 27], time of onset of the ulceration is usually not helpful in distinguishing between radiation injury and recurrent tumor. Debnam et al. [28] studied the imaging findings of 20 patients with radiation-associated soft tissue ulcerations. They found that ulcerations without adjacent enhancement failed to demonstrate evidence of recurrent tumor, either with biopsy or on follow-up imaging. This finding suggests that an ulceration without adjacent enhancement is likely benign (Figure 6(a)). When ulcerations demonstrate adjacent enhancement, careful observation is required, if biopsy is not performed, as 4 of 8 ulcerations with adjacent enhancement demonstrated recurrent tumor (Figure 6(b)), while the other 4 ulcerations were free of tumor with biopsy or on follow-up imaging.


Imaging of the Head and Neck following Radiation Treatment.

Debnam JM - Patholog Res Int (2011)

Benign and malignant soft tissue ulceration: (a) Axial contrast-enhanced CT of the oral cavity (soft tissue window) shows a benign ulceration (arrow) without an associated soft tissue mass. (b) Axial contrast-enhanced CT (soft tissue window) shows recurrent tumor characterized by irregular enhancement along the floor of the ulceration (arrows).
© Copyright Policy - open-access
Related In: Results  -  Collection

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getmorefigures.php?uid=PMC3108502&req=5

fig6: Benign and malignant soft tissue ulceration: (a) Axial contrast-enhanced CT of the oral cavity (soft tissue window) shows a benign ulceration (arrow) without an associated soft tissue mass. (b) Axial contrast-enhanced CT (soft tissue window) shows recurrent tumor characterized by irregular enhancement along the floor of the ulceration (arrows).
Mentions: Ulceration is defined as a defect, or excavation, of the surface of a tissue or organ, which is produced by the sloughing of inflammatory necrotic tissue [26]. As most necrosis and many recurrences occur within 2 years following radiation therapy [26] and the risk of injury related to radiation necrosis is greatest during the first 6–12 months after radiation therapy [21, 27], time of onset of the ulceration is usually not helpful in distinguishing between radiation injury and recurrent tumor. Debnam et al. [28] studied the imaging findings of 20 patients with radiation-associated soft tissue ulcerations. They found that ulcerations without adjacent enhancement failed to demonstrate evidence of recurrent tumor, either with biopsy or on follow-up imaging. This finding suggests that an ulceration without adjacent enhancement is likely benign (Figure 6(a)). When ulcerations demonstrate adjacent enhancement, careful observation is required, if biopsy is not performed, as 4 of 8 ulcerations with adjacent enhancement demonstrated recurrent tumor (Figure 6(b)), while the other 4 ulcerations were free of tumor with biopsy or on follow-up imaging.

Bottom Line: Squamous cell carcinoma of the head and neck occurs in approximately 40,000 patients annually in the United States and is often treated with radiation therapy.Radiological studies are obtained following treatment for head and neck malignancies to assess for recurrent tumor, posttreatment changes, and associated complications.As post-treatment imaging studies are often discussed at radiology/pathology working conferences, knowledge of the imaging appearance of radiation-associated changes in the head and neck and the terminology used by neuroradiologists may not only aid in interpretation of the pathologic specimen, but also assist in communications with neuroradiologists and referring clinicians.

View Article: PubMed Central - PubMed

Affiliation: Section of Neuroradiology, Department of Radiology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.

ABSTRACT
Squamous cell carcinoma of the head and neck occurs in approximately 40,000 patients annually in the United States and is often treated with radiation therapy. Radiological studies are obtained following treatment for head and neck malignancies to assess for recurrent tumor, posttreatment changes, and associated complications. Radiation treatment creates a difficult clinical picture for oncologists, head and neck surgeons, neuroradiologists, and neuropathologists. As post-treatment imaging studies are often discussed at radiology/pathology working conferences, knowledge of the imaging appearance of radiation-associated changes in the head and neck and the terminology used by neuroradiologists may not only aid in interpretation of the pathologic specimen, but also assist in communications with neuroradiologists and referring clinicians.

No MeSH data available.


Related in: MedlinePlus