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Carcinoma of gall bladder presenting as dermatomyositis.

Narasimhaiah DA, Premkumar JA, Moses V, Chacko G - Ann Indian Acad Neurol (2011)

Bottom Line: Dermatomyositis (DM) is a type of inflammatory myopathy that is strongly associated with a broad range of malignant disorders.The malignancies most commonly associated with DM are carcinomas of ovary, lung, stomach, colorectal and pancreas, as well as non-Hodgkin's lymphoma.An association of DM with carcinoma of the gall bladder (GB) is extremely rare with only two previously reported cases in the literature.

View Article: PubMed Central - PubMed

Affiliation: Department of General Pathology, Christian Medical College, Vellore- 632004, Tamil Nadu, India.

ABSTRACT
Cancer-related muscle diseases are usually paraneoplastic disorders. Dermatomyositis (DM) is a type of inflammatory myopathy that is strongly associated with a broad range of malignant disorders. The malignancy can occur before, concomitantly or after the onset of myositis. The malignancies most commonly associated with DM are carcinomas of ovary, lung, stomach, colorectal and pancreas, as well as non-Hodgkin's lymphoma. An association of DM with carcinoma of the gall bladder (GB) is extremely rare with only two previously reported cases in the literature. We report a case of carcinoma of GB with DM as the paraneoplastic manifestation.

No MeSH data available.


Related in: MedlinePlus

Tumor transmurally infiltrating the wall of gall bladder (H and E, ×50)
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Figure 0003: Tumor transmurally infiltrating the wall of gall bladder (H and E, ×50)

Mentions: The microscopic examination of the tumor in GB showed a transmurally infiltrating moderately differentiated adenocarcinoma [Figure 3]. The tumor showed perineural invasion, as well as extension into the adventitial adipose tissue. The enlarged lymph nodes at the porta hepatis and the neck of GB showed metastatic tumor deposits. The right lung revealed lobar pneumonia with evidence of aspiration. The microscopic examination of the rest of the organs was normal.


Carcinoma of gall bladder presenting as dermatomyositis.

Narasimhaiah DA, Premkumar JA, Moses V, Chacko G - Ann Indian Acad Neurol (2011)

Tumor transmurally infiltrating the wall of gall bladder (H and E, ×50)
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3108078&req=5

Figure 0003: Tumor transmurally infiltrating the wall of gall bladder (H and E, ×50)
Mentions: The microscopic examination of the tumor in GB showed a transmurally infiltrating moderately differentiated adenocarcinoma [Figure 3]. The tumor showed perineural invasion, as well as extension into the adventitial adipose tissue. The enlarged lymph nodes at the porta hepatis and the neck of GB showed metastatic tumor deposits. The right lung revealed lobar pneumonia with evidence of aspiration. The microscopic examination of the rest of the organs was normal.

Bottom Line: Dermatomyositis (DM) is a type of inflammatory myopathy that is strongly associated with a broad range of malignant disorders.The malignancies most commonly associated with DM are carcinomas of ovary, lung, stomach, colorectal and pancreas, as well as non-Hodgkin's lymphoma.An association of DM with carcinoma of the gall bladder (GB) is extremely rare with only two previously reported cases in the literature.

View Article: PubMed Central - PubMed

Affiliation: Department of General Pathology, Christian Medical College, Vellore- 632004, Tamil Nadu, India.

ABSTRACT
Cancer-related muscle diseases are usually paraneoplastic disorders. Dermatomyositis (DM) is a type of inflammatory myopathy that is strongly associated with a broad range of malignant disorders. The malignancy can occur before, concomitantly or after the onset of myositis. The malignancies most commonly associated with DM are carcinomas of ovary, lung, stomach, colorectal and pancreas, as well as non-Hodgkin's lymphoma. An association of DM with carcinoma of the gall bladder (GB) is extremely rare with only two previously reported cases in the literature. We report a case of carcinoma of GB with DM as the paraneoplastic manifestation.

No MeSH data available.


Related in: MedlinePlus