Forward suppression in the auditory cortex is frequency-specific.
Bottom Line: The temporal order and frequency proximity of sounds influence both their perception and neuronal responses.These effects are larger when the two sounds are spectrally similar.These data are consistent with the idea that cortical neurons receive convergent inputs with a wide range of tuning properties that can adapt independently.
Affiliation: MRC Institute of Hearing Research, University Park, Nottingham NG7 2RD, UK.Show MeSH
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Mentions: The example shown in Fig. 2C had multiple peaks in the excitatory RF. In each condition, the SCF and SBF tend towards the probe tone frequency. However, the range of conditioner tones that suppress the 8-kHz probe tone is larger than the range of conditioner tones that suppress the 2.5-kHz probe tone. There is also some suggestion that suppression for the 8-kHz probe is centred on the upper lobe in the excitatory RF, at 10 kHz. Clear multi-peaked tuning curves were relatively rare in our sample (12 units). While it was clear that suppressed tuning was biased towards the probe tone, there was frequently evidence that local features in the RF, near to the probe frequency, also had an influence on tuning. Figure 2D shows another example of a multi-peaked tuning curve in which suppression tended to gravitate towards the peak in the excitatory tuning curve that was nearest to the probe frequency (see also Fig. 5).
Affiliation: MRC Institute of Hearing Research, University Park, Nottingham NG7 2RD, UK.