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How much do you know about benign, preneoplastic, non-invasive and invasive neoplastic lesions of the urinary bladder classified according to the 2004 WHO scheme?

Montironi R, Cheng L, Scarpelli M, Mazzucchelli R, Lopez-Beltran A - Diagn Pathol (2011)

Bottom Line: The aim of this essay is the self assessment of the level of knowledge of the 2004 WHO classification of bladder neoplasms through a series of MCQs, each associated a short commentary.This paper is directed to all who are involved with the application of this classification at the anticancer research, diagnostic, prognostic and therapeutic levels, in particular to uropathologists, urologists and oncologists.

View Article: PubMed Central - HTML - PubMed

Affiliation: Section of Pathological Anatomy, School of Medicine, Polytechnic University of the Marche Region (Ancona), Ancona, Italy. r.montironi@univpm.it

ABSTRACT
The aim of this essay is the self assessment of the level of knowledge of the 2004 WHO classification of bladder neoplasms through a series of MCQs, each associated a short commentary. This paper is directed to all who are involved with the application of this classification at the anticancer research, diagnostic, prognostic and therapeutic levels, in particular to uropathologists, urologists and oncologists.

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Related in: MedlinePlus

Carcinoma in situ of the urothelium.
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Figure 6: Carcinoma in situ of the urothelium.

Mentions: Histologically CIS is characterized by architectural disorder and nuclear pleomorphism (Figure 6). The cytologically atypical cells need not involve the full thickness of the epithelium and at the minimum single malignant cells growing in a pagetoid fashion are sufficient for the diagnosis of CIS. Individual cells tend to show marked cytological atypia but increased N:C ratio is not a prerequisite (not present in the large cell type of CIS). In some cases only a few isolated cells are present clinging to the basement membrane (denuding CIS).


How much do you know about benign, preneoplastic, non-invasive and invasive neoplastic lesions of the urinary bladder classified according to the 2004 WHO scheme?

Montironi R, Cheng L, Scarpelli M, Mazzucchelli R, Lopez-Beltran A - Diagn Pathol (2011)

Carcinoma in situ of the urothelium.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3107770&req=5

Figure 6: Carcinoma in situ of the urothelium.
Mentions: Histologically CIS is characterized by architectural disorder and nuclear pleomorphism (Figure 6). The cytologically atypical cells need not involve the full thickness of the epithelium and at the minimum single malignant cells growing in a pagetoid fashion are sufficient for the diagnosis of CIS. Individual cells tend to show marked cytological atypia but increased N:C ratio is not a prerequisite (not present in the large cell type of CIS). In some cases only a few isolated cells are present clinging to the basement membrane (denuding CIS).

Bottom Line: The aim of this essay is the self assessment of the level of knowledge of the 2004 WHO classification of bladder neoplasms through a series of MCQs, each associated a short commentary.This paper is directed to all who are involved with the application of this classification at the anticancer research, diagnostic, prognostic and therapeutic levels, in particular to uropathologists, urologists and oncologists.

View Article: PubMed Central - HTML - PubMed

Affiliation: Section of Pathological Anatomy, School of Medicine, Polytechnic University of the Marche Region (Ancona), Ancona, Italy. r.montironi@univpm.it

ABSTRACT
The aim of this essay is the self assessment of the level of knowledge of the 2004 WHO classification of bladder neoplasms through a series of MCQs, each associated a short commentary. This paper is directed to all who are involved with the application of this classification at the anticancer research, diagnostic, prognostic and therapeutic levels, in particular to uropathologists, urologists and oncologists.

Show MeSH
Related in: MedlinePlus