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How much do you know about benign, preneoplastic, non-invasive and invasive neoplastic lesions of the urinary bladder classified according to the 2004 WHO scheme?

Montironi R, Cheng L, Scarpelli M, Mazzucchelli R, Lopez-Beltran A - Diagn Pathol (2011)

Bottom Line: The aim of this essay is the self assessment of the level of knowledge of the 2004 WHO classification of bladder neoplasms through a series of MCQs, each associated a short commentary.This paper is directed to all who are involved with the application of this classification at the anticancer research, diagnostic, prognostic and therapeutic levels, in particular to uropathologists, urologists and oncologists.

View Article: PubMed Central - HTML - PubMed

Affiliation: Section of Pathological Anatomy, School of Medicine, Polytechnic University of the Marche Region (Ancona), Ancona, Italy. r.montironi@univpm.it

ABSTRACT
The aim of this essay is the self assessment of the level of knowledge of the 2004 WHO classification of bladder neoplasms through a series of MCQs, each associated a short commentary. This paper is directed to all who are involved with the application of this classification at the anticancer research, diagnostic, prognostic and therapeutic levels, in particular to uropathologists, urologists and oncologists.

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Papillary urothelial hyperplasia (pseudopapillary hyperplasia).
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Figure 4: Papillary urothelial hyperplasia (pseudopapillary hyperplasia).

Mentions: In the 1998 WHO/ISUP classification, papillary hyperplasia was included as a category with the group of papillary lesions [1]. In the 2004 WHO classification, this is no longer included as a specific designation but it is recognized that hyperplasias may be flat or pseudopapillary (Figure 4) [2]. In the current classification, hyperplasia with a pseudopapillary architecture refers to a slight tenting or undulation of the urothelium lacking a well defined central fibrovascular core, although small vessels may be present at the base of the papillae. There is no significant cytologic or architectural atypia. These have most often been described in the setting of known papillary neoplasia. When identified de novo the significance regarding subsequent development of neoplasia is unknown.


How much do you know about benign, preneoplastic, non-invasive and invasive neoplastic lesions of the urinary bladder classified according to the 2004 WHO scheme?

Montironi R, Cheng L, Scarpelli M, Mazzucchelli R, Lopez-Beltran A - Diagn Pathol (2011)

Papillary urothelial hyperplasia (pseudopapillary hyperplasia).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3107770&req=5

Figure 4: Papillary urothelial hyperplasia (pseudopapillary hyperplasia).
Mentions: In the 1998 WHO/ISUP classification, papillary hyperplasia was included as a category with the group of papillary lesions [1]. In the 2004 WHO classification, this is no longer included as a specific designation but it is recognized that hyperplasias may be flat or pseudopapillary (Figure 4) [2]. In the current classification, hyperplasia with a pseudopapillary architecture refers to a slight tenting or undulation of the urothelium lacking a well defined central fibrovascular core, although small vessels may be present at the base of the papillae. There is no significant cytologic or architectural atypia. These have most often been described in the setting of known papillary neoplasia. When identified de novo the significance regarding subsequent development of neoplasia is unknown.

Bottom Line: The aim of this essay is the self assessment of the level of knowledge of the 2004 WHO classification of bladder neoplasms through a series of MCQs, each associated a short commentary.This paper is directed to all who are involved with the application of this classification at the anticancer research, diagnostic, prognostic and therapeutic levels, in particular to uropathologists, urologists and oncologists.

View Article: PubMed Central - HTML - PubMed

Affiliation: Section of Pathological Anatomy, School of Medicine, Polytechnic University of the Marche Region (Ancona), Ancona, Italy. r.montironi@univpm.it

ABSTRACT
The aim of this essay is the self assessment of the level of knowledge of the 2004 WHO classification of bladder neoplasms through a series of MCQs, each associated a short commentary. This paper is directed to all who are involved with the application of this classification at the anticancer research, diagnostic, prognostic and therapeutic levels, in particular to uropathologists, urologists and oncologists.

Show MeSH
Related in: MedlinePlus