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How much do you know about benign, preneoplastic, non-invasive and invasive neoplastic lesions of the urinary bladder classified according to the 2004 WHO scheme?

Montironi R, Cheng L, Scarpelli M, Mazzucchelli R, Lopez-Beltran A - Diagn Pathol (2011)

Bottom Line: The aim of this essay is the self assessment of the level of knowledge of the 2004 WHO classification of bladder neoplasms through a series of MCQs, each associated a short commentary.This paper is directed to all who are involved with the application of this classification at the anticancer research, diagnostic, prognostic and therapeutic levels, in particular to uropathologists, urologists and oncologists.

View Article: PubMed Central - HTML - PubMed

Affiliation: Section of Pathological Anatomy, School of Medicine, Polytechnic University of the Marche Region (Ancona), Ancona, Italy. r.montironi@univpm.it

ABSTRACT
The aim of this essay is the self assessment of the level of knowledge of the 2004 WHO classification of bladder neoplasms through a series of MCQs, each associated a short commentary. This paper is directed to all who are involved with the application of this classification at the anticancer research, diagnostic, prognostic and therapeutic levels, in particular to uropathologists, urologists and oncologists.

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Related in: MedlinePlus

Flat urothelial hyperplasia.
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Figure 2: Flat urothelial hyperplasia.

Mentions: Historically the term "hyperplasia" has been equated with counting cell layers and specifically considering the epithelium to be hyperplastic if there were more than 7 cell layers (Figure 2). It is well recognized that the apparent number of cell layers in the normal urothelium is variable and dependent on the state of contraction of the bladder wall. The 2004 classification recognizes hyperplasia as when there is a "markedly thickened mucosa without atypia." Counting cell layers is not recommended. The relationship between hyperplasia and neoplasia is unknown [2,5,6].


How much do you know about benign, preneoplastic, non-invasive and invasive neoplastic lesions of the urinary bladder classified according to the 2004 WHO scheme?

Montironi R, Cheng L, Scarpelli M, Mazzucchelli R, Lopez-Beltran A - Diagn Pathol (2011)

Flat urothelial hyperplasia.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3107770&req=5

Figure 2: Flat urothelial hyperplasia.
Mentions: Historically the term "hyperplasia" has been equated with counting cell layers and specifically considering the epithelium to be hyperplastic if there were more than 7 cell layers (Figure 2). It is well recognized that the apparent number of cell layers in the normal urothelium is variable and dependent on the state of contraction of the bladder wall. The 2004 classification recognizes hyperplasia as when there is a "markedly thickened mucosa without atypia." Counting cell layers is not recommended. The relationship between hyperplasia and neoplasia is unknown [2,5,6].

Bottom Line: The aim of this essay is the self assessment of the level of knowledge of the 2004 WHO classification of bladder neoplasms through a series of MCQs, each associated a short commentary.This paper is directed to all who are involved with the application of this classification at the anticancer research, diagnostic, prognostic and therapeutic levels, in particular to uropathologists, urologists and oncologists.

View Article: PubMed Central - HTML - PubMed

Affiliation: Section of Pathological Anatomy, School of Medicine, Polytechnic University of the Marche Region (Ancona), Ancona, Italy. r.montironi@univpm.it

ABSTRACT
The aim of this essay is the self assessment of the level of knowledge of the 2004 WHO classification of bladder neoplasms through a series of MCQs, each associated a short commentary. This paper is directed to all who are involved with the application of this classification at the anticancer research, diagnostic, prognostic and therapeutic levels, in particular to uropathologists, urologists and oncologists.

Show MeSH
Related in: MedlinePlus