Limits...
A population-based survey of Chronic REnal Disease In Turkey--the CREDIT study.

Süleymanlar G, Utaş C, Arinsoy T, Ateş K, Altun B, Altiparmak MR, Ecder T, Yilmaz ME, Çamsari T, Başçi A, Odabas AR, Serdengeçti K - Nephrol. Dial. Transplant. (2010)

Bottom Line: The overall prevalence of CKD was 15.7%; it was higher in women than men (18.4% vs. 12.8%, P < 0.001) and increased with increasing age of the subjects.The prevalence of hypertension (32.7% in the general population), diabetes (12.7%), dyslipidaemia (76.3%), obesity (20.1%) and metabolic syndrome (31.3%) was significantly higher in subjects with CKD than subjects without CKD (P < 0.001 for all).The prevalence of CKD in Turkey is 15.7%.

View Article: PubMed Central - PubMed

Affiliation: Nephrology Division, Department of Medicine, Akdeniz University Medical School, Antalya, Turkey. gulteksu@superonline.com

ABSTRACT

Background: Chronic kidney disease (CKD) is a growing health problem worldwide that leads to end-stage kidney failure and cardiovascular complications. We aimed to determine the prevalence of CKD in Turkey, and to evaluate relationships between CKD and cardiovascular risk factors in a population-based survey.

Methods: Medical data were collected through home visits and interviews. Serum creatinine, blood glucose, total cholesterol, triglycerides, HDL, LDL and uric acid were determined from 12-h fasting blood samples, and spot urine tests were performed for subjects who gave consent to laboratory evaluation.

Results: A total of 10 872 participants were included in the study. The final analysis was performed on 10 748 subjects (mean age 40.5 ± 16.3 years; 55.7% women) and excluded 124 pregnant women. A low glomerular filtration rate (GFR) (< 60 mL/min/1.73 m(2)) was present in 5.2% of the subjects who were evaluated for GFR, while microalbuminuria and macroalbuminuria were observed in 10.2% and 2% of the subjects, respectively. The presence of CKD was assessed in subjects who gave consent for urinary albumin excretion measurement (n = 8765). The overall prevalence of CKD was 15.7%; it was higher in women than men (18.4% vs. 12.8%, P < 0.001) and increased with increasing age of the subjects. The prevalence of hypertension (32.7% in the general population), diabetes (12.7%), dyslipidaemia (76.3%), obesity (20.1%) and metabolic syndrome (31.3%) was significantly higher in subjects with CKD than subjects without CKD (P < 0.001 for all).

Conclusions: The prevalence of CKD in Turkey is 15.7%. Cardiovascular risk factors were significantly more prevalent in CKD patients.

Show MeSH

Related in: MedlinePlus

Percentage of subjects according to glomerular filtration rate with respect to gender and age groups. There was a significant relation between the stage of glomerular filtration rate and age group (P < 0.001).
© Copyright Policy - creative-commons
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC3107767&req=5

fig1: Percentage of subjects according to glomerular filtration rate with respect to gender and age groups. There was a significant relation between the stage of glomerular filtration rate and age group (P < 0.001).

Mentions: Decreased kidney function, defined as a moderate or severe decrease in GFR, was detected in 4.4% of the subjects who were evaluated for GFR. A moderate decrease (GFR, 30–59 mL/min/1.73 m2) was observed in 4.1%, while a GFR of 15–29 mL/min/1.73 m2 was noted in 0.24%, and a GFR < 15 mL/min/1.73 m2 GFR in 0.13%. Increasing subject age produced a consistent increase in the prevalence of mild and moderate decreases in GFR (P < 0.001) (Figure 1).


A population-based survey of Chronic REnal Disease In Turkey--the CREDIT study.

Süleymanlar G, Utaş C, Arinsoy T, Ateş K, Altun B, Altiparmak MR, Ecder T, Yilmaz ME, Çamsari T, Başçi A, Odabas AR, Serdengeçti K - Nephrol. Dial. Transplant. (2010)

Percentage of subjects according to glomerular filtration rate with respect to gender and age groups. There was a significant relation between the stage of glomerular filtration rate and age group (P < 0.001).
© Copyright Policy - creative-commons
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3107767&req=5

fig1: Percentage of subjects according to glomerular filtration rate with respect to gender and age groups. There was a significant relation between the stage of glomerular filtration rate and age group (P < 0.001).
Mentions: Decreased kidney function, defined as a moderate or severe decrease in GFR, was detected in 4.4% of the subjects who were evaluated for GFR. A moderate decrease (GFR, 30–59 mL/min/1.73 m2) was observed in 4.1%, while a GFR of 15–29 mL/min/1.73 m2 was noted in 0.24%, and a GFR < 15 mL/min/1.73 m2 GFR in 0.13%. Increasing subject age produced a consistent increase in the prevalence of mild and moderate decreases in GFR (P < 0.001) (Figure 1).

Bottom Line: The overall prevalence of CKD was 15.7%; it was higher in women than men (18.4% vs. 12.8%, P < 0.001) and increased with increasing age of the subjects.The prevalence of hypertension (32.7% in the general population), diabetes (12.7%), dyslipidaemia (76.3%), obesity (20.1%) and metabolic syndrome (31.3%) was significantly higher in subjects with CKD than subjects without CKD (P < 0.001 for all).The prevalence of CKD in Turkey is 15.7%.

View Article: PubMed Central - PubMed

Affiliation: Nephrology Division, Department of Medicine, Akdeniz University Medical School, Antalya, Turkey. gulteksu@superonline.com

ABSTRACT

Background: Chronic kidney disease (CKD) is a growing health problem worldwide that leads to end-stage kidney failure and cardiovascular complications. We aimed to determine the prevalence of CKD in Turkey, and to evaluate relationships between CKD and cardiovascular risk factors in a population-based survey.

Methods: Medical data were collected through home visits and interviews. Serum creatinine, blood glucose, total cholesterol, triglycerides, HDL, LDL and uric acid were determined from 12-h fasting blood samples, and spot urine tests were performed for subjects who gave consent to laboratory evaluation.

Results: A total of 10 872 participants were included in the study. The final analysis was performed on 10 748 subjects (mean age 40.5 ± 16.3 years; 55.7% women) and excluded 124 pregnant women. A low glomerular filtration rate (GFR) (< 60 mL/min/1.73 m(2)) was present in 5.2% of the subjects who were evaluated for GFR, while microalbuminuria and macroalbuminuria were observed in 10.2% and 2% of the subjects, respectively. The presence of CKD was assessed in subjects who gave consent for urinary albumin excretion measurement (n = 8765). The overall prevalence of CKD was 15.7%; it was higher in women than men (18.4% vs. 12.8%, P < 0.001) and increased with increasing age of the subjects. The prevalence of hypertension (32.7% in the general population), diabetes (12.7%), dyslipidaemia (76.3%), obesity (20.1%) and metabolic syndrome (31.3%) was significantly higher in subjects with CKD than subjects without CKD (P < 0.001 for all).

Conclusions: The prevalence of CKD in Turkey is 15.7%. Cardiovascular risk factors were significantly more prevalent in CKD patients.

Show MeSH
Related in: MedlinePlus