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Correlation between an angiographic and a cardiac magnetic resonance score of myocardial jeopardy using standard and high-resolution perfusion sequences

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Evaluate the correlation between a Cardiac Magnetic Resonance (CMR) and an angiographic myocardial jeopardy score in coronary artery disease (CAD) using either a high-resolution or a standard perfusion sequence... However, recent advances, including the use of the advanced acceleration method k-t sensitivity encoding, allow myocardial perfusion imaging with unprecedented spatial resolution... The associated benefits remain to be fully described... High-resolution perfusion imaging may improve the correlation between JS and CMR findings. 40 consecutive study patients with known or suspected CAD underwent 1.5T CMR imaging and standard diagnostic XCA... Each segment was subdivided into equal endo and epicardial sub-segments... Sub-segments were assigned as 3% of the total myocardium each and classified as normal, ischaemia or scar... Percentage myocardium affected by ischaemia or scar was then calculated... There was a significant correlation between the JS and CMR score which was strongest in the high-resolution kt-TFE group; r=0.78, p=<0.0001 and appeared less strong in the st-TFE group; r=0.63, p=0.007 (figures 1 and 2)... There is a significant correlation between the anatomic JS and a functional CMR ischaemia/scar score... This correlation seems to improve with the use of a high-resolution perfusion technique... Complete correlation between the two scores would not be expected for reasons such as difficulty predicting the haemodynamic effects of anatomically moderate disease or post-revascularization when scar may be subtended by patent vessels... However, the correlation is likely to be clinically useful and using a high-resolution perfusion sequence may therefore be superior for imaging patients with CAD.

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CMR Ischaemia/Scar Score versus JS kt TFE perfusion cases
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Figure 2: CMR Ischaemia/Scar Score versus JS kt TFE perfusion cases

Mentions: There was a significant correlation between the JS and CMR score which was strongest in the high-resolution kt-TFE group; r=0.78, p=<0.0001 and appeared less strong in the st-TFE group; r=0.63, p=0.007 (figures 1 and 2).


Correlation between an angiographic and a cardiac magnetic resonance score of myocardial jeopardy using standard and high-resolution perfusion sequences
CMR Ischaemia/Scar Score versus JS kt TFE perfusion cases
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC3106662&req=5

Figure 2: CMR Ischaemia/Scar Score versus JS kt TFE perfusion cases
Mentions: There was a significant correlation between the JS and CMR score which was strongest in the high-resolution kt-TFE group; r=0.78, p=<0.0001 and appeared less strong in the st-TFE group; r=0.63, p=0.007 (figures 1 and 2).

View Article: PubMed Central - HTML

AUTOMATICALLY GENERATED EXCERPT
Please rate it.

Evaluate the correlation between a Cardiac Magnetic Resonance (CMR) and an angiographic myocardial jeopardy score in coronary artery disease (CAD) using either a high-resolution or a standard perfusion sequence... However, recent advances, including the use of the advanced acceleration method k-t sensitivity encoding, allow myocardial perfusion imaging with unprecedented spatial resolution... The associated benefits remain to be fully described... High-resolution perfusion imaging may improve the correlation between JS and CMR findings. 40 consecutive study patients with known or suspected CAD underwent 1.5T CMR imaging and standard diagnostic XCA... Each segment was subdivided into equal endo and epicardial sub-segments... Sub-segments were assigned as 3% of the total myocardium each and classified as normal, ischaemia or scar... Percentage myocardium affected by ischaemia or scar was then calculated... There was a significant correlation between the JS and CMR score which was strongest in the high-resolution kt-TFE group; r=0.78, p=<0.0001 and appeared less strong in the st-TFE group; r=0.63, p=0.007 (figures 1 and 2)... There is a significant correlation between the anatomic JS and a functional CMR ischaemia/scar score... This correlation seems to improve with the use of a high-resolution perfusion technique... Complete correlation between the two scores would not be expected for reasons such as difficulty predicting the haemodynamic effects of anatomically moderate disease or post-revascularization when scar may be subtended by patent vessels... However, the correlation is likely to be clinically useful and using a high-resolution perfusion sequence may therefore be superior for imaging patients with CAD.

No MeSH data available.


Related in: MedlinePlus