Limits...
Gender differences in response to cold pressor test assessed with velocity-encoded cine-MR imaging of the coronary sinus

View Article: PubMed Central - HTML

AUTOMATICALLY GENERATED EXCERPT
Please rate it.

Gender-specific differences in cardiovascular risk are well known, and current evidence supports an existing role of coronary endothelium function in these differences... To assess non invasively coronary endothelial function in male and female young volunteers by myocardial blood flow (MBF) measurement using coronary sinus (CS) flow quantification by velocity encoded cine MRI at rest and during cold pressor test (CPT)... Coronary sinus flow was measured at rest and during CPT using a non breath-hold velocity encoded phase contrast cine MRI (TR/TE: 45 ms / 2 ms, slice thickness:5.5mm, FOV: 250, averages:11, matrix:256, flow encoding 70cm/s, flip angle: 25°, acquisition time: 4 min, GRAPPA k-space reduction factor:4)... Coronary vascular resistance (CVR), rate pressure product and endothelium-dependent vasodilatation index (EDVI) were calculated... At baseline, MBF was 0.63 ± 0.23 mL.g.min in men and 0.79 ± 0.21 mL ·g ·min in women (P=ns) (figure 1)... During CPT, the rate pressure product in men significantly increased by 49 ± 36 % (p<0.0001) and in women by 52 ± 22 % (p<0.0001)... MBF increased significantly in both men and women by 0.22 ± 0.19 mL·g·min (p=0.0022) and by 0.73 ± 0.43 mL·g·min (p=0.0001), respectively... The increase in MBF was significantly higher in women than in men (p = 0.0012) MRI coronary sinus flow quantification for measuring myocardial blood flow revealed a higher response of MBF to CPT in women than in men.

No MeSH data available.


Comparison of myocardial blood flow (MBF) obtained at rest and after CPT in men (circle) and women (square).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC3106529&req=5

Figure 1: Comparison of myocardial blood flow (MBF) obtained at rest and after CPT in men (circle) and women (square).

Mentions: At baseline, MBF was 0.63 ± 0.23 mL.g-1.min-1 in men and 0.79 ± 0.21 mL ·g-1 ·min-1 in women (P=ns) (figure 1). During CPT, the rate pressure product in men significantly increased by 49 ± 36 % (p<0.0001) and in women by 52 ± 22 % (p<0.0001). MBF increased significantly in both men and women by 0.22 ± 0.19 mL·g-1·min-1 (p=0.0022) and by 0.73 ± 0.43 mL·g-1·min-1 (p=0.0001), respectively. The increase in MBF was significantly higher in women than in men (p = 0.0012)


Gender differences in response to cold pressor test assessed with velocity-encoded cine-MR imaging of the coronary sinus
Comparison of myocardial blood flow (MBF) obtained at rest and after CPT in men (circle) and women (square).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3106529&req=5

Figure 1: Comparison of myocardial blood flow (MBF) obtained at rest and after CPT in men (circle) and women (square).
Mentions: At baseline, MBF was 0.63 ± 0.23 mL.g-1.min-1 in men and 0.79 ± 0.21 mL ·g-1 ·min-1 in women (P=ns) (figure 1). During CPT, the rate pressure product in men significantly increased by 49 ± 36 % (p<0.0001) and in women by 52 ± 22 % (p<0.0001). MBF increased significantly in both men and women by 0.22 ± 0.19 mL·g-1·min-1 (p=0.0022) and by 0.73 ± 0.43 mL·g-1·min-1 (p=0.0001), respectively. The increase in MBF was significantly higher in women than in men (p = 0.0012)

View Article: PubMed Central - HTML

AUTOMATICALLY GENERATED EXCERPT
Please rate it.

Gender-specific differences in cardiovascular risk are well known, and current evidence supports an existing role of coronary endothelium function in these differences... To assess non invasively coronary endothelial function in male and female young volunteers by myocardial blood flow (MBF) measurement using coronary sinus (CS) flow quantification by velocity encoded cine MRI at rest and during cold pressor test (CPT)... Coronary sinus flow was measured at rest and during CPT using a non breath-hold velocity encoded phase contrast cine MRI (TR/TE: 45 ms / 2 ms, slice thickness:5.5mm, FOV: 250, averages:11, matrix:256, flow encoding 70cm/s, flip angle: 25°, acquisition time: 4 min, GRAPPA k-space reduction factor:4)... Coronary vascular resistance (CVR), rate pressure product and endothelium-dependent vasodilatation index (EDVI) were calculated... At baseline, MBF was 0.63 ± 0.23 mL.g.min in men and 0.79 ± 0.21 mL ·g ·min in women (P=ns) (figure 1)... During CPT, the rate pressure product in men significantly increased by 49 ± 36 % (p<0.0001) and in women by 52 ± 22 % (p<0.0001)... MBF increased significantly in both men and women by 0.22 ± 0.19 mL·g·min (p=0.0022) and by 0.73 ± 0.43 mL·g·min (p=0.0001), respectively... The increase in MBF was significantly higher in women than in men (p = 0.0012) MRI coronary sinus flow quantification for measuring myocardial blood flow revealed a higher response of MBF to CPT in women than in men.

No MeSH data available.