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Reproducibility of coronary vessel wall imaging techniques

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Coronary wall thickness measurements must be highly reproducible to be useful in longitudinal studies... While 2D turbo-spin-echo (TSE) and spiral techniques are commonly used, 3D techniques reduce partial-volume effects and allow greater vessel coverage... Cross-sectional right coronary artery wall images were obtained in 10 healthy subjects on a Siemens 1.5T Avanto scanner using dark-blood prepared B2B-RMC 3D spiral imaging, navigator-gated 2D TSE imaging and navigator-gated 2D spiral imaging... B2B-RMC 3D spiral acquisitions acquired 8x3.0mm slices (16x1.5mm reconstructed) and 2D techniques acquired 1x6mm slice... A single slice was selected from each 3D acquisition for comparison with the 2D acquisitions... The intra- and inter-observer reproducibility of this measurement technique was analysed in 20 images... Example images from one subject are shown in figure 1. 92% of acquisitions were successful... RE, wall thickness and acquisition durations are presented in Table 1... B2B-RMC RE was less variable and significantly higher than navigator gating (99.6±1.2%vs.39.0±7.5%,p<0.0001) and there was no significant difference in vessel wall thickness between techniques(p=ns)... Mean intra-/inter-observer wall thickness difference was 0.04±0.09mm/0.05±0.08mm... ICCs were good for the 2D techniques and excellent for the 3D technique... The high RE of B2B-RMC enables reproducible 3D coronary wall assessment within a reasonable duration which will permit improved assessment of atherosclerotic disease.

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Example images obtained from one volunteer using all techniques. The4x1.5mm slices shown of the 3D acquisition correspond to the single 6mm slices of the 2D acquisitions. There is a high degree of visual similarity between the initial (upper) and repeat images (below) acquired 29 days apart. Respiratory efficiency in the initial studies was 100% B2B-RMC, 40% 2D spiral and 38* TSE. In the repeat studies respiratory efficiency was 100% B2B-RMC, 55% 2D spiral and 40% 2D TSE.
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Figure 1: Example images obtained from one volunteer using all techniques. The4x1.5mm slices shown of the 3D acquisition correspond to the single 6mm slices of the 2D acquisitions. There is a high degree of visual similarity between the initial (upper) and repeat images (below) acquired 29 days apart. Respiratory efficiency in the initial studies was 100% B2B-RMC, 40% 2D spiral and 38* TSE. In the repeat studies respiratory efficiency was 100% B2B-RMC, 55% 2D spiral and 40% 2D TSE.

Mentions: Example images from one subject are shown in figure 1. 92% of acquisitions were successful. RE, wall thickness and acquisition durations are presented in Table 1. B2B-RMC RE was less variable and significantly higher than navigator gating (99.6±1.2%vs.39.0±7.5%,p<0.0001) and there was no significant difference in vessel wall thickness between techniques(p=ns).


Reproducibility of coronary vessel wall imaging techniques
Example images obtained from one volunteer using all techniques. The4x1.5mm slices shown of the 3D acquisition correspond to the single 6mm slices of the 2D acquisitions. There is a high degree of visual similarity between the initial (upper) and repeat images (below) acquired 29 days apart. Respiratory efficiency in the initial studies was 100% B2B-RMC, 40% 2D spiral and 38* TSE. In the repeat studies respiratory efficiency was 100% B2B-RMC, 55% 2D spiral and 40% 2D TSE.
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Related In: Results  -  Collection

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Figure 1: Example images obtained from one volunteer using all techniques. The4x1.5mm slices shown of the 3D acquisition correspond to the single 6mm slices of the 2D acquisitions. There is a high degree of visual similarity between the initial (upper) and repeat images (below) acquired 29 days apart. Respiratory efficiency in the initial studies was 100% B2B-RMC, 40% 2D spiral and 38* TSE. In the repeat studies respiratory efficiency was 100% B2B-RMC, 55% 2D spiral and 40% 2D TSE.
Mentions: Example images from one subject are shown in figure 1. 92% of acquisitions were successful. RE, wall thickness and acquisition durations are presented in Table 1. B2B-RMC RE was less variable and significantly higher than navigator gating (99.6±1.2%vs.39.0±7.5%,p<0.0001) and there was no significant difference in vessel wall thickness between techniques(p=ns).

View Article: PubMed Central - HTML

AUTOMATICALLY GENERATED EXCERPT
Please rate it.

Coronary wall thickness measurements must be highly reproducible to be useful in longitudinal studies... While 2D turbo-spin-echo (TSE) and spiral techniques are commonly used, 3D techniques reduce partial-volume effects and allow greater vessel coverage... Cross-sectional right coronary artery wall images were obtained in 10 healthy subjects on a Siemens 1.5T Avanto scanner using dark-blood prepared B2B-RMC 3D spiral imaging, navigator-gated 2D TSE imaging and navigator-gated 2D spiral imaging... B2B-RMC 3D spiral acquisitions acquired 8x3.0mm slices (16x1.5mm reconstructed) and 2D techniques acquired 1x6mm slice... A single slice was selected from each 3D acquisition for comparison with the 2D acquisitions... The intra- and inter-observer reproducibility of this measurement technique was analysed in 20 images... Example images from one subject are shown in figure 1. 92% of acquisitions were successful... RE, wall thickness and acquisition durations are presented in Table 1... B2B-RMC RE was less variable and significantly higher than navigator gating (99.6±1.2%vs.39.0±7.5%,p<0.0001) and there was no significant difference in vessel wall thickness between techniques(p=ns)... Mean intra-/inter-observer wall thickness difference was 0.04±0.09mm/0.05±0.08mm... ICCs were good for the 2D techniques and excellent for the 3D technique... The high RE of B2B-RMC enables reproducible 3D coronary wall assessment within a reasonable duration which will permit improved assessment of atherosclerotic disease.

No MeSH data available.


Related in: MedlinePlus