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Can real-time cmr provide adequate morphologic or functional data? A real-time CMR/SSFP comparison trial

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The objective of this trial was to assess the accuracy of cardiac magnetic resonance (CMR) images obtained via real-time CMR (RT-CMR) (GE: MR Echo) imaging sequences in comparison to steady-state free precession (SSFP)... Diagnostically useful cardiac MR images are currently obtained using SSFP imaging sequences... Clinically relevant cardiac parameters (table 2) were measured in both diastole and systole utilizing SSFP and RT-CMR sequences... Measurements were made using common, consistent anatomic locations in both methods, were performed in random order, and were blinded to the results from the other sequence... Cardiac dimensions measured in each imaging modality were then compared using a paired t-test as well as a Passing and Bablock regression analysis... The slope and intercept for a Passing and Bablock regression are shown below and demonstrate no significant deviation from linearity (ALL P VALUES N >0.10)... RT-CMR exhibits a consistent, though not statistically significant underestimation of LV areas in both systole and diastole... Furthermore, analysis of the relationship between the percentage difference of these methods showed this difference to be highly, significantly correlated... RT-CMR provides clinically useful morphologic and functional LV and RV data compared to SSFP imaging... In this highly variable clinical population of pediatric and adults patients referred for CMR studies, there was no significant difference between SSFP and RT-CMR measurements with the exception of LV diastolic area.

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A regression of % difference in measured values between SSFP and RT-CMR between LV diastolic area and LV systolic area. The intercept = -0.041 (P=0.14) and the slope =0.553 (P=0.019), with an analysis of variance significance level of P=0.019.
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Figure 2: A regression of % difference in measured values between SSFP and RT-CMR between LV diastolic area and LV systolic area. The intercept = -0.041 (P=0.14) and the slope =0.553 (P=0.019), with an analysis of variance significance level of P=0.019.

Mentions: With the exception of LVEDA, our data show no statistical difference between the measurements obtained using either CMR sequence (figures 1 and 2). The slope and intercept for a Passing and Bablock regression are shown below and demonstrate no significant deviation from linearity (ALL P VALUES N >0.10). RT-CMR exhibits a consistent, though not statistically significant underestimation of LV areas in both systole and diastole. Furthermore, analysis of the relationship between the percentage difference of these methods showed this difference to be highly, significantly correlated.


Can real-time cmr provide adequate morphologic or functional data? A real-time CMR/SSFP comparison trial
A regression of % difference in measured values between SSFP and RT-CMR between LV diastolic area and LV systolic area. The intercept = -0.041 (P=0.14) and the slope =0.553 (P=0.019), with an analysis of variance significance level of P=0.019.
© Copyright Policy - open-access
Related In: Results  -  Collection

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getmorefigures.php?uid=PMC3106482&req=5

Figure 2: A regression of % difference in measured values between SSFP and RT-CMR between LV diastolic area and LV systolic area. The intercept = -0.041 (P=0.14) and the slope =0.553 (P=0.019), with an analysis of variance significance level of P=0.019.
Mentions: With the exception of LVEDA, our data show no statistical difference between the measurements obtained using either CMR sequence (figures 1 and 2). The slope and intercept for a Passing and Bablock regression are shown below and demonstrate no significant deviation from linearity (ALL P VALUES N >0.10). RT-CMR exhibits a consistent, though not statistically significant underestimation of LV areas in both systole and diastole. Furthermore, analysis of the relationship between the percentage difference of these methods showed this difference to be highly, significantly correlated.

View Article: PubMed Central - HTML

AUTOMATICALLY GENERATED EXCERPT
Please rate it.

The objective of this trial was to assess the accuracy of cardiac magnetic resonance (CMR) images obtained via real-time CMR (RT-CMR) (GE: MR Echo) imaging sequences in comparison to steady-state free precession (SSFP)... Diagnostically useful cardiac MR images are currently obtained using SSFP imaging sequences... Clinically relevant cardiac parameters (table 2) were measured in both diastole and systole utilizing SSFP and RT-CMR sequences... Measurements were made using common, consistent anatomic locations in both methods, were performed in random order, and were blinded to the results from the other sequence... Cardiac dimensions measured in each imaging modality were then compared using a paired t-test as well as a Passing and Bablock regression analysis... The slope and intercept for a Passing and Bablock regression are shown below and demonstrate no significant deviation from linearity (ALL P VALUES N >0.10)... RT-CMR exhibits a consistent, though not statistically significant underestimation of LV areas in both systole and diastole... Furthermore, analysis of the relationship between the percentage difference of these methods showed this difference to be highly, significantly correlated... RT-CMR provides clinically useful morphologic and functional LV and RV data compared to SSFP imaging... In this highly variable clinical population of pediatric and adults patients referred for CMR studies, there was no significant difference between SSFP and RT-CMR measurements with the exception of LV diastolic area.

No MeSH data available.


Related in: MedlinePlus