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Active left atrial emptying: assessment by cine and velocity encoded magnetic resonance imaging

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Measurements of active LA emptying are typically performed by echocardiography in clinical routine... Cine-MRI was performed in the four- and two chamber view... Maximal, mid-diastolic and minimal LA volumes were calculated using the biplane area-length method... Flow curves were generated using the freely available software Segment... Active LA emptying was defined as the volume of late diastolic flow (shaded area under the A-wave, Figure 1)... Correlation and agreement was assessed between cine- and VENC-MRI measurements of LA emptying volumes... A strong correlation was found between biplane long-axis cine- and VENC-MRI measurements of active LA emptying volume (r=0.72, P<0.0001)... Bland-Altman analysis revealed a mean difference of 3.4±9.1 ml between both methods... The intra- and inter-observer variances were significantly larger for measurements by cine-MRI compared to measurements by VENC-MRI (22.5 ml2 vs. 1.6 ml2 and 45.5 ml2 vs. 5.8 ml2; P<0.0001)... Measurements of active LA emptying agree well between biplane long-axis cine- and VENC-MRI... However, measurements by VENC-MRI provide a significantly better reproducibility and should preferably be used.

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Assessment of active LA emptying volume by VENC-MRI
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Figure 1: Assessment of active LA emptying volume by VENC-MRI

Mentions: This study included 82 patients with sinus rhythm. Cine-MRI was performed in the four- and two chamber view. Maximal, mid-diastolic and minimal LA volumes were calculated using the biplane area-length method. Active LA emptying volume was defined by cine-MRI as the difference between mid-diastolic and minimal LA volume. Transmitral flow was assessed by VENC-MRI. Flow curves were generated using the freely available software Segment. Active LA emptying was defined as the volume of late diastolic flow (shaded area under the A-wave, Figure 1). Correlation and agreement was assessed between cine- and VENC-MRI measurements of LA emptying volumes. Reproducibility was evaluated by calculating the intra- and inter-observer variances.


Active left atrial emptying: assessment by cine and velocity encoded magnetic resonance imaging
Assessment of active LA emptying volume by VENC-MRI
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3106447&req=5

Figure 1: Assessment of active LA emptying volume by VENC-MRI
Mentions: This study included 82 patients with sinus rhythm. Cine-MRI was performed in the four- and two chamber view. Maximal, mid-diastolic and minimal LA volumes were calculated using the biplane area-length method. Active LA emptying volume was defined by cine-MRI as the difference between mid-diastolic and minimal LA volume. Transmitral flow was assessed by VENC-MRI. Flow curves were generated using the freely available software Segment. Active LA emptying was defined as the volume of late diastolic flow (shaded area under the A-wave, Figure 1). Correlation and agreement was assessed between cine- and VENC-MRI measurements of LA emptying volumes. Reproducibility was evaluated by calculating the intra- and inter-observer variances.

View Article: PubMed Central - HTML

AUTOMATICALLY GENERATED EXCERPT
Please rate it.

Measurements of active LA emptying are typically performed by echocardiography in clinical routine... Cine-MRI was performed in the four- and two chamber view... Maximal, mid-diastolic and minimal LA volumes were calculated using the biplane area-length method... Flow curves were generated using the freely available software Segment... Active LA emptying was defined as the volume of late diastolic flow (shaded area under the A-wave, Figure 1)... Correlation and agreement was assessed between cine- and VENC-MRI measurements of LA emptying volumes... A strong correlation was found between biplane long-axis cine- and VENC-MRI measurements of active LA emptying volume (r=0.72, P<0.0001)... Bland-Altman analysis revealed a mean difference of 3.4±9.1 ml between both methods... The intra- and inter-observer variances were significantly larger for measurements by cine-MRI compared to measurements by VENC-MRI (22.5 ml2 vs. 1.6 ml2 and 45.5 ml2 vs. 5.8 ml2; P<0.0001)... Measurements of active LA emptying agree well between biplane long-axis cine- and VENC-MRI... However, measurements by VENC-MRI provide a significantly better reproducibility and should preferably be used.

No MeSH data available.