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Liquefying panniculitis associated with intraductal papillary mucinous neoplasm.

Qian DH, Shen BY, Zhan X, Peng C, Cheng D - JRSM Short Rep (2011)

View Article: PubMed Central - PubMed

Affiliation: Department of Hapato-Bilio-Pancreatic Surgery, Rui Jin Hospital, affiliated to Shanghai Jiao Tong University , Shanghai City , China.

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We report a case of a 64-year-old man who presented with liquefying panniculitis associated with intraductal papillary mucinous neoplasm (IPMN) after the Whipple operation... A 64-year-old man presented with a weight loss of 10 kg over 1 year and insomnia... The patient received the pancreatoduodenectomy on 3 March 2010 and the postoperative pathology gave a definite diagnosis of IPMN of the pancreas (Figure 1). 0.1 mg of octreotide injected subcutaneously every 8 h was postoperatively administered to suppress pancreatic secretion and decrease the risk of pancreatic fistula... On postoperative day 2, on the right lower limb skin a localized erythema appeared which slowly became larger, but the subcutaneous lesion did not bulge onto the surface of the skin... We increased octreotide intravenous infusion to 0.6 mg every day and simultaneously used the Medrol (glucocorticoid, 20 mg/24h), Ulinastatin (protease inhibitors) and antibiotics... No new nodules appeared and the original nodules did not change... The patient had to receive the second operation on 1 April 2010... Introperatively, we found the pelvic cavity filled with brown oily necrotic liquids of about 50 mL... In 2006, Gahr et al. presented the first case of intraductal papillary mucinous adenoma of the pancreas associated with lobular panniculitis... Hereon, we presented a case of liquefying panniculitis associated with IPMN... Compared with domestic cases, there are more foreign cases reported... Most of them associated with pancreatic diseases have poor prognosis... In this case, skin lesions appeared postoperative and the operation may also be a predisposing risky factor for liquefying panniculitis and the exact mechanism needs to be further explored... None declared Shanghai Committee of Science and Technology, China (grant no. 09140902300) Written consent to publication was obtained from the patient or next of kin BS All authors contributed equally The authors thank Xiao-chun Wang for the pathological pictures and Wang Hui for his help John Ajo and Gareth Morris-Stiff

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The photomicrograph of a resected specimen showing dilation of the pancreatic duct and ductal epithelial papillary hyperplasia, without obvious atypical and invasive growth (H&E, ×100)
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SHORTS-10-141F1: The photomicrograph of a resected specimen showing dilation of the pancreatic duct and ductal epithelial papillary hyperplasia, without obvious atypical and invasive growth (H&E, ×100)

Mentions: Tumor markers including CEA, CA125, AFP and CA199 were not elevated. The patient's serum levels of amylase, lipase and calcium were normal. The patient received the pancreatoduodenectomy on 3 March 2010 and the postoperative pathology gave a definite diagnosis of IPMN of the pancreas (Figure 1).


Liquefying panniculitis associated with intraductal papillary mucinous neoplasm.

Qian DH, Shen BY, Zhan X, Peng C, Cheng D - JRSM Short Rep (2011)

The photomicrograph of a resected specimen showing dilation of the pancreatic duct and ductal epithelial papillary hyperplasia, without obvious atypical and invasive growth (H&E, ×100)
© Copyright Policy - creative-commons
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3105454&req=5

SHORTS-10-141F1: The photomicrograph of a resected specimen showing dilation of the pancreatic duct and ductal epithelial papillary hyperplasia, without obvious atypical and invasive growth (H&E, ×100)
Mentions: Tumor markers including CEA, CA125, AFP and CA199 were not elevated. The patient's serum levels of amylase, lipase and calcium were normal. The patient received the pancreatoduodenectomy on 3 March 2010 and the postoperative pathology gave a definite diagnosis of IPMN of the pancreas (Figure 1).

View Article: PubMed Central - PubMed

Affiliation: Department of Hapato-Bilio-Pancreatic Surgery, Rui Jin Hospital, affiliated to Shanghai Jiao Tong University , Shanghai City , China.

AUTOMATICALLY GENERATED EXCERPT
Please rate it.

We report a case of a 64-year-old man who presented with liquefying panniculitis associated with intraductal papillary mucinous neoplasm (IPMN) after the Whipple operation... A 64-year-old man presented with a weight loss of 10 kg over 1 year and insomnia... The patient received the pancreatoduodenectomy on 3 March 2010 and the postoperative pathology gave a definite diagnosis of IPMN of the pancreas (Figure 1). 0.1 mg of octreotide injected subcutaneously every 8 h was postoperatively administered to suppress pancreatic secretion and decrease the risk of pancreatic fistula... On postoperative day 2, on the right lower limb skin a localized erythema appeared which slowly became larger, but the subcutaneous lesion did not bulge onto the surface of the skin... We increased octreotide intravenous infusion to 0.6 mg every day and simultaneously used the Medrol (glucocorticoid, 20 mg/24h), Ulinastatin (protease inhibitors) and antibiotics... No new nodules appeared and the original nodules did not change... The patient had to receive the second operation on 1 April 2010... Introperatively, we found the pelvic cavity filled with brown oily necrotic liquids of about 50 mL... In 2006, Gahr et al. presented the first case of intraductal papillary mucinous adenoma of the pancreas associated with lobular panniculitis... Hereon, we presented a case of liquefying panniculitis associated with IPMN... Compared with domestic cases, there are more foreign cases reported... Most of them associated with pancreatic diseases have poor prognosis... In this case, skin lesions appeared postoperative and the operation may also be a predisposing risky factor for liquefying panniculitis and the exact mechanism needs to be further explored... None declared Shanghai Committee of Science and Technology, China (grant no. 09140902300) Written consent to publication was obtained from the patient or next of kin BS All authors contributed equally The authors thank Xiao-chun Wang for the pathological pictures and Wang Hui for his help John Ajo and Gareth Morris-Stiff

No MeSH data available.


Related in: MedlinePlus