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Confidence interval based parameter estimation--a new SOCR applet and activity.

Christou N, Dinov ID - PLoS ONE (2011)

Bottom Line: The SOCR confidence interval applet enables the user to empirically explore and investigate the effects of the confidence-level, the sample-size and parameter of interest on the corresponding confidence interval.Two applications of the new interval estimation computational library are presented.The first one is a simulation of confidence interval estimating the US unemployment rate and the second application demonstrates the computations of point and interval estimates of hippocampal surface complexity for Alzheimers disease patients, mild cognitive impairment subjects and asymptomatic controls.

View Article: PubMed Central - PubMed

Affiliation: Department of Statistics, University of California Los Angeles, Los Angeles, California, United States of America.

ABSTRACT
Many scientific investigations depend on obtaining data-driven, accurate, robust and computationally-tractable parameter estimates. In the face of unavoidable intrinsic variability, there are different algorithmic approaches, prior assumptions and fundamental principles for computing point and interval estimates. Efficient and reliable parameter estimation is critical in making inference about observable experiments, summarizing process characteristics and prediction of experimental behaviors. In this manuscript, we demonstrate simulation, construction, validation and interpretation of confidence intervals, under various assumptions, using the interactive web-based tools provided by the Statistics Online Computational Resource (http://www.SOCR.ucla.edu). Specifically, we present confidence interval examples for population means, with known or unknown population standard deviation; population variance; population proportion (exact and approximate), as well as confidence intervals based on bootstrapping or the asymptotic properties of the maximum likelihood estimates. Like all SOCR resources, these confidence interval resources may be openly accessed via an Internet-connected Java-enabled browser. The SOCR confidence interval applet enables the user to empirically explore and investigate the effects of the confidence-level, the sample-size and parameter of interest on the corresponding confidence interval. Two applications of the new interval estimation computational library are presented. The first one is a simulation of confidence interval estimating the US unemployment rate and the second application demonstrates the computations of point and interval estimates of hippocampal surface complexity for Alzheimers disease patients, mild cognitive impairment subjects and asymptomatic controls.

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Related in: MedlinePlus

Modeling the unemployment data using generalized Beta distribution.The coordinate axes represent X  =  (values) unemployment rate and Y  =  (frequencies) number of months (1959–2009) when unemployment rate was at the given X value.
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pone-0019178-g020: Modeling the unemployment data using generalized Beta distribution.The coordinate axes represent X  =  (values) unemployment rate and Y  =  (frequencies) number of months (1959–2009) when unemployment rate was at the given X value.

Mentions: Next, we fit in a generalized Beta distribution model to the frequency distribution of the unemployment data. Figure 20 shows the Beta model fit density curve juxtaposed on top of the unemployment data distribution. The maximum likelihood estimates of the four Beta distribution parameters are obtained using the SOCR Modeler (http://socr.ucla.edu/htmls/SOCR_Modeler.html):


Confidence interval based parameter estimation--a new SOCR applet and activity.

Christou N, Dinov ID - PLoS ONE (2011)

Modeling the unemployment data using generalized Beta distribution.The coordinate axes represent X  =  (values) unemployment rate and Y  =  (frequencies) number of months (1959–2009) when unemployment rate was at the given X value.
© Copyright Policy
Related In: Results  -  Collection

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getmorefigures.php?uid=PMC3104980&req=5

pone-0019178-g020: Modeling the unemployment data using generalized Beta distribution.The coordinate axes represent X  =  (values) unemployment rate and Y  =  (frequencies) number of months (1959–2009) when unemployment rate was at the given X value.
Mentions: Next, we fit in a generalized Beta distribution model to the frequency distribution of the unemployment data. Figure 20 shows the Beta model fit density curve juxtaposed on top of the unemployment data distribution. The maximum likelihood estimates of the four Beta distribution parameters are obtained using the SOCR Modeler (http://socr.ucla.edu/htmls/SOCR_Modeler.html):

Bottom Line: The SOCR confidence interval applet enables the user to empirically explore and investigate the effects of the confidence-level, the sample-size and parameter of interest on the corresponding confidence interval.Two applications of the new interval estimation computational library are presented.The first one is a simulation of confidence interval estimating the US unemployment rate and the second application demonstrates the computations of point and interval estimates of hippocampal surface complexity for Alzheimers disease patients, mild cognitive impairment subjects and asymptomatic controls.

View Article: PubMed Central - PubMed

Affiliation: Department of Statistics, University of California Los Angeles, Los Angeles, California, United States of America.

ABSTRACT
Many scientific investigations depend on obtaining data-driven, accurate, robust and computationally-tractable parameter estimates. In the face of unavoidable intrinsic variability, there are different algorithmic approaches, prior assumptions and fundamental principles for computing point and interval estimates. Efficient and reliable parameter estimation is critical in making inference about observable experiments, summarizing process characteristics and prediction of experimental behaviors. In this manuscript, we demonstrate simulation, construction, validation and interpretation of confidence intervals, under various assumptions, using the interactive web-based tools provided by the Statistics Online Computational Resource (http://www.SOCR.ucla.edu). Specifically, we present confidence interval examples for population means, with known or unknown population standard deviation; population variance; population proportion (exact and approximate), as well as confidence intervals based on bootstrapping or the asymptotic properties of the maximum likelihood estimates. Like all SOCR resources, these confidence interval resources may be openly accessed via an Internet-connected Java-enabled browser. The SOCR confidence interval applet enables the user to empirically explore and investigate the effects of the confidence-level, the sample-size and parameter of interest on the corresponding confidence interval. Two applications of the new interval estimation computational library are presented. The first one is a simulation of confidence interval estimating the US unemployment rate and the second application demonstrates the computations of point and interval estimates of hippocampal surface complexity for Alzheimers disease patients, mild cognitive impairment subjects and asymptomatic controls.

Show MeSH
Related in: MedlinePlus