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Frosted branch angiitis diagnosed as neuro-behçet: a diagnostic and etiologic dilemma.

Portero A, Herreras JM - Case Rep Ophthalmol (2011)

Bottom Line: Description, diagnosis, angiogram imaging and follow-up of a 28-year-old female with FBA. 'Frosted branch angiitis' is a clinical term applied to three conditions: infiltration of vessels by malignant cells, and sheathing of vessels either secondary to an active disorder or subsequently to a previous inflammatory disease.Our patient's history of two optic neuropathies and the lack of demyelinating signs in neuroimaging made us consider FBA in the context of neuro-Behçet.Recognition of the category of FBA from the clinical signs is essential to establish the correct diagnosis and prescribe the appropriate treatment.

View Article: PubMed Central - PubMed

Affiliation: Ophthalmology Department, University Hospital of Valladolid and IOBA, Valladolid, Spain.

ABSTRACT

Purpose: To report a case of frosted branch angiitis (FBA) secondary to neuro-Behçet.

Methods: Description, diagnosis, angiogram imaging and follow-up of a 28-year-old female with FBA.

Results: 'Frosted branch angiitis' is a clinical term applied to three conditions: infiltration of vessels by malignant cells, and sheathing of vessels either secondary to an active disorder or subsequently to a previous inflammatory disease. Our patient's history of two optic neuropathies and the lack of demyelinating signs in neuroimaging made us consider FBA in the context of neuro-Behçet.

Conclusion: Recognition of the category of FBA from the clinical signs is essential to establish the correct diagnosis and prescribe the appropriate treatment.

No MeSH data available.


Related in: MedlinePlus

Both first-line figures show a frosted branch angiitis image before starting with steroids. Both second-line figures disclose a relevant enhancement only 24 h after starting steroids. Both third-line figures show the macular stars OU, temporal focus of optic nerve atrophy and temporal peripheral hemorrhages 7 days after starting steroids and disclosed with OCT (both last-line figures).
© Copyright Policy - open-access
Related In: Results  -  Collection

License 1 - License 2
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Figure 1: Both first-line figures show a frosted branch angiitis image before starting with steroids. Both second-line figures disclose a relevant enhancement only 24 h after starting steroids. Both third-line figures show the macular stars OU, temporal focus of optic nerve atrophy and temporal peripheral hemorrhages 7 days after starting steroids and disclosed with OCT (both last-line figures).

Mentions: The ophthalmic examination disclosed decreased visual acuities (VA) OU: 20/200 OD and 20/120 in the left eye (OS). Ocular motility and pupil function were normal. The intraocular pressure OU was normal along the process. On slit-lamp examination, inflammation was seen in the anterior chamber (cells 2+) and in the vitreous (cells 2+) OU. Fundus examination showed severe sheathing of retinal vessels, retinal hemorrhages, Roth's spots and macular edema OU (fig. 1).


Frosted branch angiitis diagnosed as neuro-behçet: a diagnostic and etiologic dilemma.

Portero A, Herreras JM - Case Rep Ophthalmol (2011)

Both first-line figures show a frosted branch angiitis image before starting with steroids. Both second-line figures disclose a relevant enhancement only 24 h after starting steroids. Both third-line figures show the macular stars OU, temporal focus of optic nerve atrophy and temporal peripheral hemorrhages 7 days after starting steroids and disclosed with OCT (both last-line figures).
© Copyright Policy - open-access
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC3104864&req=5

Figure 1: Both first-line figures show a frosted branch angiitis image before starting with steroids. Both second-line figures disclose a relevant enhancement only 24 h after starting steroids. Both third-line figures show the macular stars OU, temporal focus of optic nerve atrophy and temporal peripheral hemorrhages 7 days after starting steroids and disclosed with OCT (both last-line figures).
Mentions: The ophthalmic examination disclosed decreased visual acuities (VA) OU: 20/200 OD and 20/120 in the left eye (OS). Ocular motility and pupil function were normal. The intraocular pressure OU was normal along the process. On slit-lamp examination, inflammation was seen in the anterior chamber (cells 2+) and in the vitreous (cells 2+) OU. Fundus examination showed severe sheathing of retinal vessels, retinal hemorrhages, Roth's spots and macular edema OU (fig. 1).

Bottom Line: Description, diagnosis, angiogram imaging and follow-up of a 28-year-old female with FBA. 'Frosted branch angiitis' is a clinical term applied to three conditions: infiltration of vessels by malignant cells, and sheathing of vessels either secondary to an active disorder or subsequently to a previous inflammatory disease.Our patient's history of two optic neuropathies and the lack of demyelinating signs in neuroimaging made us consider FBA in the context of neuro-Behçet.Recognition of the category of FBA from the clinical signs is essential to establish the correct diagnosis and prescribe the appropriate treatment.

View Article: PubMed Central - PubMed

Affiliation: Ophthalmology Department, University Hospital of Valladolid and IOBA, Valladolid, Spain.

ABSTRACT

Purpose: To report a case of frosted branch angiitis (FBA) secondary to neuro-Behçet.

Methods: Description, diagnosis, angiogram imaging and follow-up of a 28-year-old female with FBA.

Results: 'Frosted branch angiitis' is a clinical term applied to three conditions: infiltration of vessels by malignant cells, and sheathing of vessels either secondary to an active disorder or subsequently to a previous inflammatory disease. Our patient's history of two optic neuropathies and the lack of demyelinating signs in neuroimaging made us consider FBA in the context of neuro-Behçet.

Conclusion: Recognition of the category of FBA from the clinical signs is essential to establish the correct diagnosis and prescribe the appropriate treatment.

No MeSH data available.


Related in: MedlinePlus