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Early-stage mucinous sweat gland adenocarcinoma of eyelid.

Nizawa T, Oshitari T, Kimoto R, Kajita F, Yotsukura J, Asanagi K, Baba T, Takahashi Y, Oide T, Kiyokawa T, Kishimoto T, Yamamoto S - Clin Ophthalmol (2011)

Bottom Line: He was referred to our hospital with a diagnosis of a swollen chalazion.Six months after the surgery, no recurrence has been observed.A complete surgical excision is recommended.

View Article: PubMed Central - PubMed

Affiliation: Department of Ophthalmology and Visual Science, Chiba University Graduate School of Medicine, Chuo-ku, Chiba, Japan.

ABSTRACT
We present the findings of an early-stage primary mucinous sweat gland adenocarcinoma in the lower eyelid of a Japanese patient. The patient was a 73-year-old man who had had a nodule on the left lower eyelid for two years. He was referred to our hospital with a diagnosis of a swollen chalazion. The clinical and histopathological records were reviewed and the mass was excised. Histopathological examination revealed a mucinous sweat gland adenocarcinoma. Postoperative magnetic resonance imaging and positron emission tomography excluded systemic metastases. After the histopathological findings, a complete surgical excision of the margins of the adenocarcinoma was performed, with histopathological confirmation of negative margins. After the final histopathological examination, the patient was diagnosed with a primary mucinous sweat gland adenocarcinoma of the left eyelid. Six months after the surgery, no recurrence has been observed. Because the appearance of mucinous sweat gland adenocarcinoma of the eyelid is quite variable, the final diagnosis can only be made by histopathological examination. A complete surgical excision is recommended.

No MeSH data available.


Related in: MedlinePlus

Histopathological findings from the specimen. Floating clumps of cuboidal cells with focal duct formation in the abundant mucin lakes (arrows) indicate a sweat gland adenocarcinoma.
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f2-opth-5-687: Histopathological findings from the specimen. Floating clumps of cuboidal cells with focal duct formation in the abundant mucin lakes (arrows) indicate a sweat gland adenocarcinoma.

Mentions: We performed nodule excision with clinically visible margins. The tentative diagnosis during the operation was a hemangioma and not a chalazion or benign granuloma. The nodule was horizontally extended and attached to the tarsal plate. Histopathology revealed floating clumps of cuboidal cells with focal duct formation in the abundant mucin lakes (Figure 2). Postoperative magnetic resonance imaging and positron emission tomography scanning excluded systemic tumors. Thus, the final diagnosis of his tumor was a primary mucinous sweat gland adenocarcinoma of the left lower eyelid. Because of the histopathological diagnosis, we performed a second operation to excise the margins of the tumor until the tissue was histologically confirmed to be negative. Six months after the second operation, no recurrence or metastasis was found (Figure 1B).


Early-stage mucinous sweat gland adenocarcinoma of eyelid.

Nizawa T, Oshitari T, Kimoto R, Kajita F, Yotsukura J, Asanagi K, Baba T, Takahashi Y, Oide T, Kiyokawa T, Kishimoto T, Yamamoto S - Clin Ophthalmol (2011)

Histopathological findings from the specimen. Floating clumps of cuboidal cells with focal duct formation in the abundant mucin lakes (arrows) indicate a sweat gland adenocarcinoma.
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC3104798&req=5

f2-opth-5-687: Histopathological findings from the specimen. Floating clumps of cuboidal cells with focal duct formation in the abundant mucin lakes (arrows) indicate a sweat gland adenocarcinoma.
Mentions: We performed nodule excision with clinically visible margins. The tentative diagnosis during the operation was a hemangioma and not a chalazion or benign granuloma. The nodule was horizontally extended and attached to the tarsal plate. Histopathology revealed floating clumps of cuboidal cells with focal duct formation in the abundant mucin lakes (Figure 2). Postoperative magnetic resonance imaging and positron emission tomography scanning excluded systemic tumors. Thus, the final diagnosis of his tumor was a primary mucinous sweat gland adenocarcinoma of the left lower eyelid. Because of the histopathological diagnosis, we performed a second operation to excise the margins of the tumor until the tissue was histologically confirmed to be negative. Six months after the second operation, no recurrence or metastasis was found (Figure 1B).

Bottom Line: He was referred to our hospital with a diagnosis of a swollen chalazion.Six months after the surgery, no recurrence has been observed.A complete surgical excision is recommended.

View Article: PubMed Central - PubMed

Affiliation: Department of Ophthalmology and Visual Science, Chiba University Graduate School of Medicine, Chuo-ku, Chiba, Japan.

ABSTRACT
We present the findings of an early-stage primary mucinous sweat gland adenocarcinoma in the lower eyelid of a Japanese patient. The patient was a 73-year-old man who had had a nodule on the left lower eyelid for two years. He was referred to our hospital with a diagnosis of a swollen chalazion. The clinical and histopathological records were reviewed and the mass was excised. Histopathological examination revealed a mucinous sweat gland adenocarcinoma. Postoperative magnetic resonance imaging and positron emission tomography excluded systemic metastases. After the histopathological findings, a complete surgical excision of the margins of the adenocarcinoma was performed, with histopathological confirmation of negative margins. After the final histopathological examination, the patient was diagnosed with a primary mucinous sweat gland adenocarcinoma of the left eyelid. Six months after the surgery, no recurrence has been observed. Because the appearance of mucinous sweat gland adenocarcinoma of the eyelid is quite variable, the final diagnosis can only be made by histopathological examination. A complete surgical excision is recommended.

No MeSH data available.


Related in: MedlinePlus