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Influence of ischemia on visual function in patients with branch retinal vein occlusion and macular edema.

Noma H, Funatsu H, Mimura T, Shimada K - Clin Ophthalmol (2011)

Bottom Line: Mean visual acuity and macular sensitivity within the central subfield were not significantly correlated with the nonperfused area.However, the macular sensitivity within the central 5 subfields and all 9 subfields showed significant negative correlations with the nonperfused area.In conclusion, evaluation of both the fovea and the entire macular region may be important in patients with ischemic BRVO.

View Article: PubMed Central - PubMed

Affiliation: Department of Ophthalmology, Yachiyo Medical Center, Tokyo Women's Medical University, Owada-shinden, Chiba, Japan. nomahide@tymc.ac.jp

ABSTRACT
Visual function and retinal morphology were investigated to elucidate the influence of ischemia in patients with branch retinal vein occlusion (BRVO) and macular edema. In 41 consecutive patients with BRVO aged 68.9 ± 10.0 years (22 women and 19 men), the area of capillary nonperfusion was measured by fluorescein angiography. Retinal thickness and retinal volume were measured by optical coherence tomography, and mean retinal sensitivity was calculated for each of 9 macular subfields. Mean visual acuity and macular sensitivity within the central subfield were not significantly correlated with the nonperfused area. However, the macular sensitivity within the central 5 subfields and all 9 subfields showed significant negative correlations with the nonperfused area. Also, macular thickness and volume within all 9 subfields were significantly correlated with the nonperfused area. In conclusion, evaluation of both the fovea and the entire macular region may be important in patients with ischemic BRVO.

No MeSH data available.


Related in: MedlinePlus

Correlation between best-corrected visual acuity (BCVA) converted to the logarithm of the minimum angle of resolution scale (logMAR) and the nonperfused area. The visual acuity (logMAR) was not significantly correlated with the nonperfused area in BRVO patients with macular edema (ρ = 0.16, P = 0.317).
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f1-opth-5-679: Correlation between best-corrected visual acuity (BCVA) converted to the logarithm of the minimum angle of resolution scale (logMAR) and the nonperfused area. The visual acuity (logMAR) was not significantly correlated with the nonperfused area in BRVO patients with macular edema (ρ = 0.16, P = 0.317).

Mentions: Visual acuity (logMAR) was not significantly correlated with the nonperfused area (ρ = 0.16, P = 0.317) (Figure 1). Macular sensitivity within the 10° and 20° fields showed significant negative correlations with the nonperfused area (ρ = −0.35, P = 0.021, and ρ = −0.36, P = 0.020, respectively), but the macular sensitivity within the central 4° field was not significantly correlated with the nonperfused area (ρ =−0.25, P = 0.108) (Figures 2A–2C). Although macular thickness within the 20° field was significantly correlated with the nonperfused area (ρ = 0.33, P = 0.037), the macular thickness within the central 4° or 10° fields was not significantly correlated with the nonperfused area (ρ = 0.28, P = 0.071, and ρ = 0.27, P = 0.092, respectively) (Figures 3A–3C). Likewise, macular volume within the 20° field was significantly correlated with the nonperfused area (ρ = 0.36, P = 0.019), but macular volume within the central 4° or 10° fields was not (ρ = 0.29, P = 0.062, and ρ = 0.26, P = 0.103, respectively) (Figures 4A–4C).


Influence of ischemia on visual function in patients with branch retinal vein occlusion and macular edema.

Noma H, Funatsu H, Mimura T, Shimada K - Clin Ophthalmol (2011)

Correlation between best-corrected visual acuity (BCVA) converted to the logarithm of the minimum angle of resolution scale (logMAR) and the nonperfused area. The visual acuity (logMAR) was not significantly correlated with the nonperfused area in BRVO patients with macular edema (ρ = 0.16, P = 0.317).
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC3104797&req=5

f1-opth-5-679: Correlation between best-corrected visual acuity (BCVA) converted to the logarithm of the minimum angle of resolution scale (logMAR) and the nonperfused area. The visual acuity (logMAR) was not significantly correlated with the nonperfused area in BRVO patients with macular edema (ρ = 0.16, P = 0.317).
Mentions: Visual acuity (logMAR) was not significantly correlated with the nonperfused area (ρ = 0.16, P = 0.317) (Figure 1). Macular sensitivity within the 10° and 20° fields showed significant negative correlations with the nonperfused area (ρ = −0.35, P = 0.021, and ρ = −0.36, P = 0.020, respectively), but the macular sensitivity within the central 4° field was not significantly correlated with the nonperfused area (ρ =−0.25, P = 0.108) (Figures 2A–2C). Although macular thickness within the 20° field was significantly correlated with the nonperfused area (ρ = 0.33, P = 0.037), the macular thickness within the central 4° or 10° fields was not significantly correlated with the nonperfused area (ρ = 0.28, P = 0.071, and ρ = 0.27, P = 0.092, respectively) (Figures 3A–3C). Likewise, macular volume within the 20° field was significantly correlated with the nonperfused area (ρ = 0.36, P = 0.019), but macular volume within the central 4° or 10° fields was not (ρ = 0.29, P = 0.062, and ρ = 0.26, P = 0.103, respectively) (Figures 4A–4C).

Bottom Line: Mean visual acuity and macular sensitivity within the central subfield were not significantly correlated with the nonperfused area.However, the macular sensitivity within the central 5 subfields and all 9 subfields showed significant negative correlations with the nonperfused area.In conclusion, evaluation of both the fovea and the entire macular region may be important in patients with ischemic BRVO.

View Article: PubMed Central - PubMed

Affiliation: Department of Ophthalmology, Yachiyo Medical Center, Tokyo Women's Medical University, Owada-shinden, Chiba, Japan. nomahide@tymc.ac.jp

ABSTRACT
Visual function and retinal morphology were investigated to elucidate the influence of ischemia in patients with branch retinal vein occlusion (BRVO) and macular edema. In 41 consecutive patients with BRVO aged 68.9 ± 10.0 years (22 women and 19 men), the area of capillary nonperfusion was measured by fluorescein angiography. Retinal thickness and retinal volume were measured by optical coherence tomography, and mean retinal sensitivity was calculated for each of 9 macular subfields. Mean visual acuity and macular sensitivity within the central subfield were not significantly correlated with the nonperfused area. However, the macular sensitivity within the central 5 subfields and all 9 subfields showed significant negative correlations with the nonperfused area. Also, macular thickness and volume within all 9 subfields were significantly correlated with the nonperfused area. In conclusion, evaluation of both the fovea and the entire macular region may be important in patients with ischemic BRVO.

No MeSH data available.


Related in: MedlinePlus