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Evaluation of spectral domain and time domain optical coherence tomography findings in toxoplasmic retinochoroiditis.

Diniz B, Regatieri C, Andrade R, Maia A - Clin Ophthalmol (2011)

Bottom Line: Perilesional subretinal fluid was observed in two patients.The median retinal thickness significantly decreased at the retinochoroiditis lesion (P = 0.0004), and all the patients remained with disorganized retinal layers reflectivity at follow up.SD-OCT is superior in evaluating retinal changes associated with ocular toxoplasmosis.

View Article: PubMed Central - PubMed

Affiliation: Department of Ophthalmology, Federal University of São Paulo, São Paulo, Brazil. drbrunodiniz@yahoo.com

ABSTRACT

Purpose: To investigate spectral domain optical coherence tomography (SD-OCT) findings and compare them with time domain (TD)-OCT imaging of macula and retinochoroiditis lesions of patients with toxoplasmosis.

Design: Prospective cross-sectional study.

Methods: Ten eyes of 10 patients with active toxoplasmic retinochoroiditis were included. Morphologic features from the macula and retinochoroiditis lesions were obtained at baseline and at 6-week follow up. Scan acquisition protocols for TD-OCT included raster and radial lines through the retinochoroiditis lesion, fast macular, and a linear scan from the lesion to the fovea, whereas the acquisition protocols for SD-OCT also included horizontal volume scans at the lesion site and at the macula. Thickness measurements obtained by SD-OCT were analyzed.

Results: At baseline, macular serous retinal detachment was observed in five patients; two of them only seen by SD-OCT. Retinochoroidal lesions were 4260 μm distant from the fovea on average (R = 681-7130) and this distance had an indirect correlation to the presence of macular detachment. Epiretinal membrane and vitreo-macular traction were also observed. The posterior hyaloid was not identified in four patients by TD-OCT and only in one by SD-OCT at baseline. Perilesional subretinal fluid was observed in two patients. The median retinal thickness significantly decreased at the retinochoroiditis lesion (P = 0.0004), and all the patients remained with disorganized retinal layers reflectivity at follow up.

Conclusion: SD-OCT is a useful tool in the diagnosis of macular changes related with toxoplasmic retinochoroiditis. SD-OCT is superior in evaluating retinal changes associated with ocular toxoplasmosis.

No MeSH data available.


Related in: MedlinePlus

Fundus photography at baseline. Radial scans at baseline by SD-OCT A) and TD-OCT C) shows increased thickness at the lesion site and foveal subretinal fluid. At follow up, residual fluid (arrowhead) both by SD-OCT B) and TD-OCT D). Partial detachment of the posterior hyaloid and adhesion to the fovea only seen by SD-OCT (asterisk).Abbreviations: OCT, optical coherence tomography; SD, spectral domain; TD, time domain.
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f2-opth-5-645: Fundus photography at baseline. Radial scans at baseline by SD-OCT A) and TD-OCT C) shows increased thickness at the lesion site and foveal subretinal fluid. At follow up, residual fluid (arrowhead) both by SD-OCT B) and TD-OCT D). Partial detachment of the posterior hyaloid and adhesion to the fovea only seen by SD-OCT (asterisk).Abbreviations: OCT, optical coherence tomography; SD, spectral domain; TD, time domain.

Mentions: The average foveal thickness decreased from 344 ± 59.68 μm to 208 ± 10.40 μm at the follow-up evaluation, mainly because of the subfoveal retinal detachment regression. At the 6-week follow up, the macula remained with a small retinal detachment in one patient who presented a discrete vitreous adhesion to the fovea (Figure 2).


Evaluation of spectral domain and time domain optical coherence tomography findings in toxoplasmic retinochoroiditis.

Diniz B, Regatieri C, Andrade R, Maia A - Clin Ophthalmol (2011)

Fundus photography at baseline. Radial scans at baseline by SD-OCT A) and TD-OCT C) shows increased thickness at the lesion site and foveal subretinal fluid. At follow up, residual fluid (arrowhead) both by SD-OCT B) and TD-OCT D). Partial detachment of the posterior hyaloid and adhesion to the fovea only seen by SD-OCT (asterisk).Abbreviations: OCT, optical coherence tomography; SD, spectral domain; TD, time domain.
© Copyright Policy
Related In: Results  -  Collection

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getmorefigures.php?uid=PMC3104792&req=5

f2-opth-5-645: Fundus photography at baseline. Radial scans at baseline by SD-OCT A) and TD-OCT C) shows increased thickness at the lesion site and foveal subretinal fluid. At follow up, residual fluid (arrowhead) both by SD-OCT B) and TD-OCT D). Partial detachment of the posterior hyaloid and adhesion to the fovea only seen by SD-OCT (asterisk).Abbreviations: OCT, optical coherence tomography; SD, spectral domain; TD, time domain.
Mentions: The average foveal thickness decreased from 344 ± 59.68 μm to 208 ± 10.40 μm at the follow-up evaluation, mainly because of the subfoveal retinal detachment regression. At the 6-week follow up, the macula remained with a small retinal detachment in one patient who presented a discrete vitreous adhesion to the fovea (Figure 2).

Bottom Line: Perilesional subretinal fluid was observed in two patients.The median retinal thickness significantly decreased at the retinochoroiditis lesion (P = 0.0004), and all the patients remained with disorganized retinal layers reflectivity at follow up.SD-OCT is superior in evaluating retinal changes associated with ocular toxoplasmosis.

View Article: PubMed Central - PubMed

Affiliation: Department of Ophthalmology, Federal University of São Paulo, São Paulo, Brazil. drbrunodiniz@yahoo.com

ABSTRACT

Purpose: To investigate spectral domain optical coherence tomography (SD-OCT) findings and compare them with time domain (TD)-OCT imaging of macula and retinochoroiditis lesions of patients with toxoplasmosis.

Design: Prospective cross-sectional study.

Methods: Ten eyes of 10 patients with active toxoplasmic retinochoroiditis were included. Morphologic features from the macula and retinochoroiditis lesions were obtained at baseline and at 6-week follow up. Scan acquisition protocols for TD-OCT included raster and radial lines through the retinochoroiditis lesion, fast macular, and a linear scan from the lesion to the fovea, whereas the acquisition protocols for SD-OCT also included horizontal volume scans at the lesion site and at the macula. Thickness measurements obtained by SD-OCT were analyzed.

Results: At baseline, macular serous retinal detachment was observed in five patients; two of them only seen by SD-OCT. Retinochoroidal lesions were 4260 μm distant from the fovea on average (R = 681-7130) and this distance had an indirect correlation to the presence of macular detachment. Epiretinal membrane and vitreo-macular traction were also observed. The posterior hyaloid was not identified in four patients by TD-OCT and only in one by SD-OCT at baseline. Perilesional subretinal fluid was observed in two patients. The median retinal thickness significantly decreased at the retinochoroiditis lesion (P = 0.0004), and all the patients remained with disorganized retinal layers reflectivity at follow up.

Conclusion: SD-OCT is a useful tool in the diagnosis of macular changes related with toxoplasmic retinochoroiditis. SD-OCT is superior in evaluating retinal changes associated with ocular toxoplasmosis.

No MeSH data available.


Related in: MedlinePlus