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Kodamaea ohmeri tricuspid valve endocarditis with right ventricular inflow obstruction in a neonate with structurally normal heart.

Sundaram PS, Bijulal S, Tharakan JA, Antony M - Ann Pediatr Cardiol (2011)

Bottom Line: The yeast Kodamaea (Pichia) ohmeri is a rare human pathogen with infrequent report of neonatal infection.The patient was referred to our institute after having ICU stay of 18 days in another hospital for necrotizing enterocolitis and was found to have obstructive tricuspid valve mass and fungemia with Kodamaea ohmeri.In spite of the treatment, patient developed sepsis with disseminated intravascular coagulation and could not be revived.

View Article: PubMed Central - PubMed

Affiliation: Department of Cardiology, SCTIMST, Thiruvananthapuram, India.

ABSTRACT
The yeast Kodamaea (Pichia) ohmeri is a rare human pathogen with infrequent report of neonatal infection. Native valve endocarditis by Kodamaea ohmeri is extremely rare. The current case report describes a case of fatal nosocomial native valve endocarditis without any structural heart defects in a 40dayold baby. The patient was referred to our institute after having ICU stay of 18 days in another hospital for necrotizing enterocolitis and was found to have obstructive tricuspid valve mass and fungemia with Kodamaea ohmeri. In spite of the treatment, patient developed sepsis with disseminated intravascular coagulation and could not be revived.

No MeSH data available.


Related in: MedlinePlus

Cases so far reported worldwide. Only 20 cases reported so far largely due to under recognition of this potentially treatable organism
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Figure 2: Cases so far reported worldwide. Only 20 cases reported so far largely due to under recognition of this potentially treatable organism

Mentions: Cases so far reported [Figure 2] are from immunocompromised hosts with presence of invasive devices. It was first isolated in a 48 year old, diabetic, female patient.[7] In India, this is the second case, other case being a preterm baby with hyaline membrane disease.[8] K. ohmeri infection responds to the removal of the devices, catheter, etc., as it is mostly associated with invasive devices, Out of the three neonatal infections described so far, one responded to the removal of the catheter without antifungal treatment,[9] one responded to liposomal amphotericin-B, and the other baby succumbed to disseminated intravascular coagulation.


Kodamaea ohmeri tricuspid valve endocarditis with right ventricular inflow obstruction in a neonate with structurally normal heart.

Sundaram PS, Bijulal S, Tharakan JA, Antony M - Ann Pediatr Cardiol (2011)

Cases so far reported worldwide. Only 20 cases reported so far largely due to under recognition of this potentially treatable organism
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3104542&req=5

Figure 2: Cases so far reported worldwide. Only 20 cases reported so far largely due to under recognition of this potentially treatable organism
Mentions: Cases so far reported [Figure 2] are from immunocompromised hosts with presence of invasive devices. It was first isolated in a 48 year old, diabetic, female patient.[7] In India, this is the second case, other case being a preterm baby with hyaline membrane disease.[8] K. ohmeri infection responds to the removal of the devices, catheter, etc., as it is mostly associated with invasive devices, Out of the three neonatal infections described so far, one responded to the removal of the catheter without antifungal treatment,[9] one responded to liposomal amphotericin-B, and the other baby succumbed to disseminated intravascular coagulation.

Bottom Line: The yeast Kodamaea (Pichia) ohmeri is a rare human pathogen with infrequent report of neonatal infection.The patient was referred to our institute after having ICU stay of 18 days in another hospital for necrotizing enterocolitis and was found to have obstructive tricuspid valve mass and fungemia with Kodamaea ohmeri.In spite of the treatment, patient developed sepsis with disseminated intravascular coagulation and could not be revived.

View Article: PubMed Central - PubMed

Affiliation: Department of Cardiology, SCTIMST, Thiruvananthapuram, India.

ABSTRACT
The yeast Kodamaea (Pichia) ohmeri is a rare human pathogen with infrequent report of neonatal infection. Native valve endocarditis by Kodamaea ohmeri is extremely rare. The current case report describes a case of fatal nosocomial native valve endocarditis without any structural heart defects in a 40dayold baby. The patient was referred to our institute after having ICU stay of 18 days in another hospital for necrotizing enterocolitis and was found to have obstructive tricuspid valve mass and fungemia with Kodamaea ohmeri. In spite of the treatment, patient developed sepsis with disseminated intravascular coagulation and could not be revived.

No MeSH data available.


Related in: MedlinePlus