Limits...
Clinical features of re-emerging hepatitis A: an analysis of patients hospitalized during an urban epidemic in Korea.

Choi HK, Song YG, Kim CO, Shin SY, Chin BS, Han SH, Jin SJ, Chae YT, Baek JH, Kim SB, Kim do Y, Park JY, Kim JM, Choi JY - Yonsei Med. J. (2011)

Bottom Line: From April 2008 to November 2008, many cases of hepatitis A were reported in Seoul and Gyeonggi Province in Korea.Furthermore, the rate of severe or fulminant hepatitis have significantly increased during the latest epidemic (13.4% vs. 5.2%, p=0.044).Therefore, widespread use of vaccine is warranted to reduce the burden of hepatitis A in Korea.

View Article: PubMed Central - PubMed

Affiliation: Department of Internal Medicine, Yonsei University College of Medicine, 250 Seongsan-ro, Seodaemun-gu, Seoul 120-752, Korea.

ABSTRACT
From April 2008 to November 2008, many cases of hepatitis A were reported in Seoul and Gyeonggi Province in Korea. Furthermore, the rate of severe or fulminant hepatitis have significantly increased during the latest epidemic (13.4% vs. 5.2%, p=0.044). Therefore, widespread use of vaccine is warranted to reduce the burden of hepatitis A in Korea.

Show MeSH

Related in: MedlinePlus

Reported annual number of hepatitis A patients in Seoul and Gyeonggi Province.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC3104460&req=5

Figure 1: Reported annual number of hepatitis A patients in Seoul and Gyeonggi Province.

Mentions: In Korea, hepatitis A is a disease that must be reported to the district public health authority. Since April 2008, the incidence of hepatitis A has increased, particularly in Seoul and the adjacent areas in Gyeonggi Province (Fig. 1).1 Therefore, we considered this as an epidemic of hepatitis A. At that time, more patients with hepatitis A have been admitted to Severance Hospital, a tertiary teaching hospital in Seoul, Korea (Fig. 2). During this period, many physicians felt that severity, mortality and complications of hepatitis A increased compared with previous period. In the present study, we analyzed clinical features of acute hepatitis A patients who were hospitalized during the latest epidemic. The aim of the present study was to verify an increment of severe cases in recent hepatitis A epidemic and to discuss strategies to prevent hepatitis A in Korea.


Clinical features of re-emerging hepatitis A: an analysis of patients hospitalized during an urban epidemic in Korea.

Choi HK, Song YG, Kim CO, Shin SY, Chin BS, Han SH, Jin SJ, Chae YT, Baek JH, Kim SB, Kim do Y, Park JY, Kim JM, Choi JY - Yonsei Med. J. (2011)

Reported annual number of hepatitis A patients in Seoul and Gyeonggi Province.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3104460&req=5

Figure 1: Reported annual number of hepatitis A patients in Seoul and Gyeonggi Province.
Mentions: In Korea, hepatitis A is a disease that must be reported to the district public health authority. Since April 2008, the incidence of hepatitis A has increased, particularly in Seoul and the adjacent areas in Gyeonggi Province (Fig. 1).1 Therefore, we considered this as an epidemic of hepatitis A. At that time, more patients with hepatitis A have been admitted to Severance Hospital, a tertiary teaching hospital in Seoul, Korea (Fig. 2). During this period, many physicians felt that severity, mortality and complications of hepatitis A increased compared with previous period. In the present study, we analyzed clinical features of acute hepatitis A patients who were hospitalized during the latest epidemic. The aim of the present study was to verify an increment of severe cases in recent hepatitis A epidemic and to discuss strategies to prevent hepatitis A in Korea.

Bottom Line: From April 2008 to November 2008, many cases of hepatitis A were reported in Seoul and Gyeonggi Province in Korea.Furthermore, the rate of severe or fulminant hepatitis have significantly increased during the latest epidemic (13.4% vs. 5.2%, p=0.044).Therefore, widespread use of vaccine is warranted to reduce the burden of hepatitis A in Korea.

View Article: PubMed Central - PubMed

Affiliation: Department of Internal Medicine, Yonsei University College of Medicine, 250 Seongsan-ro, Seodaemun-gu, Seoul 120-752, Korea.

ABSTRACT
From April 2008 to November 2008, many cases of hepatitis A were reported in Seoul and Gyeonggi Province in Korea. Furthermore, the rate of severe or fulminant hepatitis have significantly increased during the latest epidemic (13.4% vs. 5.2%, p=0.044). Therefore, widespread use of vaccine is warranted to reduce the burden of hepatitis A in Korea.

Show MeSH
Related in: MedlinePlus