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Successful use of squeezed-fat grafts to correct a breast affected by Poland syndrome.

Yang H, Lee H - Aesthetic Plast Surg (2010)

Bottom Line: After surgery, several small cysts and minimal calcifications were present but no significant complications.In conclusion, higher condensation of fat tissues through squeezing centrifugation would help to achieve better results in volume maintenance and reduce complications.The study experiments with squeezed fat simply suggest a hypothesis that squeezing centrifugation could select healthier cells through pressure disruption of relatively thinner membranes of larger, more vulnerable and more mature fat cells.

View Article: PubMed Central - PubMed

Affiliation: Kangnam Plastic Surgery, Shinsa-Dong 577-7, Kangnam-Gu, Seoul, South Korea.

ABSTRACT
This study attempted to reconstruct deformities of a Poland syndrome patient using autologous fat tissues. All injected fat tissues were condensed by squeezing centrifugation. Operations were performed four times with intervals over 6 months. The total injection volume was 972 ml, and the maintained volume of 628 ml was measured by means of a magnetic resonance image (MRI). The entire follow-up period was 4.5 years. After surgery, several small cysts and minimal calcifications were present but no significant complications. The cosmetic outcomes and volume maintenance rates were excellent despite the overlapped large-volume injections. In conclusion, higher condensation of fat tissues through squeezing centrifugation would help to achieve better results in volume maintenance and reduce complications. It is necessary, however, to perform more comparative studies with many clinical cases for a more scientific analysis. The study experiments with squeezed fat simply suggest a hypothesis that squeezing centrifugation could select healthier cells through pressure disruption of relatively thinner membranes of larger, more vulnerable and more mature fat cells.

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A (a,b) Simple centrifuged fat. a: X50. b: X100. (c,d) Squeezed fat. c: X50. d: X100. Violet (nucleus). Pink red (cytoplasm). B Comparison of the fat cell size in the simple centrifuged fat and squeezed fat by measuring the number of pixels using the Adobe Photoshop CS2 program (Adobe, CA, USA). C Number of pixels used by the Adobe Photoshop CS2 program. To assess the size of the Coleman fat and the squeezed fat quantitatively, we randomly selected 30 single fat cells from five fat photos (×100) in each group and then measured the pixel numbers of each fat image used for the polygonal Lasso Tool in the Adobe Photoshop CS2 program
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Fig9: A (a,b) Simple centrifuged fat. a: X50. b: X100. (c,d) Squeezed fat. c: X50. d: X100. Violet (nucleus). Pink red (cytoplasm). B Comparison of the fat cell size in the simple centrifuged fat and squeezed fat by measuring the number of pixels using the Adobe Photoshop CS2 program (Adobe, CA, USA). C Number of pixels used by the Adobe Photoshop CS2 program. To assess the size of the Coleman fat and the squeezed fat quantitatively, we randomly selected 30 single fat cells from five fat photos (×100) in each group and then measured the pixel numbers of each fat image used for the polygonal Lasso Tool in the Adobe Photoshop CS2 program

Mentions: As a result, the survival rate for injected squeezed fat was significantly higher than for the fats of other groups (Fig. 8a–c). The average cell size in the squeezed fat was significantly smaller than in the centrifuged fat (Fig. 9a–c). It may be thought that the findings emerged by coincidence, but it is important to note the involvement of scaffolds and cell signals in the growth of undifferentiated stem cells and body tissues. Therefore, we suggest that the more destructed forms of fat tissues can be regarded as the more exaggerated experimental models of destructed fat. Gross tissue destruction usually indicates a reduction in tissue viability, but our destruction method of squeezing fat did not reduce tissue viability.Fig. 8


Successful use of squeezed-fat grafts to correct a breast affected by Poland syndrome.

Yang H, Lee H - Aesthetic Plast Surg (2010)

A (a,b) Simple centrifuged fat. a: X50. b: X100. (c,d) Squeezed fat. c: X50. d: X100. Violet (nucleus). Pink red (cytoplasm). B Comparison of the fat cell size in the simple centrifuged fat and squeezed fat by measuring the number of pixels using the Adobe Photoshop CS2 program (Adobe, CA, USA). C Number of pixels used by the Adobe Photoshop CS2 program. To assess the size of the Coleman fat and the squeezed fat quantitatively, we randomly selected 30 single fat cells from five fat photos (×100) in each group and then measured the pixel numbers of each fat image used for the polygonal Lasso Tool in the Adobe Photoshop CS2 program
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Related In: Results  -  Collection

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getmorefigures.php?uid=PMC3104005&req=5

Fig9: A (a,b) Simple centrifuged fat. a: X50. b: X100. (c,d) Squeezed fat. c: X50. d: X100. Violet (nucleus). Pink red (cytoplasm). B Comparison of the fat cell size in the simple centrifuged fat and squeezed fat by measuring the number of pixels using the Adobe Photoshop CS2 program (Adobe, CA, USA). C Number of pixels used by the Adobe Photoshop CS2 program. To assess the size of the Coleman fat and the squeezed fat quantitatively, we randomly selected 30 single fat cells from five fat photos (×100) in each group and then measured the pixel numbers of each fat image used for the polygonal Lasso Tool in the Adobe Photoshop CS2 program
Mentions: As a result, the survival rate for injected squeezed fat was significantly higher than for the fats of other groups (Fig. 8a–c). The average cell size in the squeezed fat was significantly smaller than in the centrifuged fat (Fig. 9a–c). It may be thought that the findings emerged by coincidence, but it is important to note the involvement of scaffolds and cell signals in the growth of undifferentiated stem cells and body tissues. Therefore, we suggest that the more destructed forms of fat tissues can be regarded as the more exaggerated experimental models of destructed fat. Gross tissue destruction usually indicates a reduction in tissue viability, but our destruction method of squeezing fat did not reduce tissue viability.Fig. 8

Bottom Line: After surgery, several small cysts and minimal calcifications were present but no significant complications.In conclusion, higher condensation of fat tissues through squeezing centrifugation would help to achieve better results in volume maintenance and reduce complications.The study experiments with squeezed fat simply suggest a hypothesis that squeezing centrifugation could select healthier cells through pressure disruption of relatively thinner membranes of larger, more vulnerable and more mature fat cells.

View Article: PubMed Central - PubMed

Affiliation: Kangnam Plastic Surgery, Shinsa-Dong 577-7, Kangnam-Gu, Seoul, South Korea.

ABSTRACT
This study attempted to reconstruct deformities of a Poland syndrome patient using autologous fat tissues. All injected fat tissues were condensed by squeezing centrifugation. Operations were performed four times with intervals over 6 months. The total injection volume was 972 ml, and the maintained volume of 628 ml was measured by means of a magnetic resonance image (MRI). The entire follow-up period was 4.5 years. After surgery, several small cysts and minimal calcifications were present but no significant complications. The cosmetic outcomes and volume maintenance rates were excellent despite the overlapped large-volume injections. In conclusion, higher condensation of fat tissues through squeezing centrifugation would help to achieve better results in volume maintenance and reduce complications. It is necessary, however, to perform more comparative studies with many clinical cases for a more scientific analysis. The study experiments with squeezed fat simply suggest a hypothesis that squeezing centrifugation could select healthier cells through pressure disruption of relatively thinner membranes of larger, more vulnerable and more mature fat cells.

Show MeSH
Related in: MedlinePlus