Limits...
Successful use of squeezed-fat grafts to correct a breast affected by Poland syndrome.

Yang H, Lee H - Aesthetic Plast Surg (2010)

Bottom Line: After surgery, several small cysts and minimal calcifications were present but no significant complications.In conclusion, higher condensation of fat tissues through squeezing centrifugation would help to achieve better results in volume maintenance and reduce complications.The study experiments with squeezed fat simply suggest a hypothesis that squeezing centrifugation could select healthier cells through pressure disruption of relatively thinner membranes of larger, more vulnerable and more mature fat cells.

View Article: PubMed Central - PubMed

Affiliation: Kangnam Plastic Surgery, Shinsa-Dong 577-7, Kangnam-Gu, Seoul, South Korea.

ABSTRACT
This study attempted to reconstruct deformities of a Poland syndrome patient using autologous fat tissues. All injected fat tissues were condensed by squeezing centrifugation. Operations were performed four times with intervals over 6 months. The total injection volume was 972 ml, and the maintained volume of 628 ml was measured by means of a magnetic resonance image (MRI). The entire follow-up period was 4.5 years. After surgery, several small cysts and minimal calcifications were present but no significant complications. The cosmetic outcomes and volume maintenance rates were excellent despite the overlapped large-volume injections. In conclusion, higher condensation of fat tissues through squeezing centrifugation would help to achieve better results in volume maintenance and reduce complications. It is necessary, however, to perform more comparative studies with many clinical cases for a more scientific analysis. The study experiments with squeezed fat simply suggest a hypothesis that squeezing centrifugation could select healthier cells through pressure disruption of relatively thinner membranes of larger, more vulnerable and more mature fat cells.

Show MeSH

Related in: MedlinePlus

Morphologic analysis comparing simple centrifuged fat and squeezed fat. A (a,c,d) Left: Simple centrifuged fat. Right: Squeezed fat. bUpper: Squeezed fat. Lower: Simple centrifuged fat. B Comparative analysis of the remaining fat volumes of simple centrifuged fat versus squeezed fat. C Graph showing the percentage of the remaining fat volume after 4 and 8 weeks in simple centrifuged fat and squeezed fat, respectively
© Copyright Policy
Related In: Results  -  Collection


getmorefigures.php?uid=PMC3104005&req=5

Fig8: Morphologic analysis comparing simple centrifuged fat and squeezed fat. A (a,c,d) Left: Simple centrifuged fat. Right: Squeezed fat. bUpper: Squeezed fat. Lower: Simple centrifuged fat. B Comparative analysis of the remaining fat volumes of simple centrifuged fat versus squeezed fat. C Graph showing the percentage of the remaining fat volume after 4 and 8 weeks in simple centrifuged fat and squeezed fat, respectively

Mentions: As a result, the survival rate for injected squeezed fat was significantly higher than for the fats of other groups (Fig. 8a–c). The average cell size in the squeezed fat was significantly smaller than in the centrifuged fat (Fig. 9a–c). It may be thought that the findings emerged by coincidence, but it is important to note the involvement of scaffolds and cell signals in the growth of undifferentiated stem cells and body tissues. Therefore, we suggest that the more destructed forms of fat tissues can be regarded as the more exaggerated experimental models of destructed fat. Gross tissue destruction usually indicates a reduction in tissue viability, but our destruction method of squeezing fat did not reduce tissue viability.Fig. 8


Successful use of squeezed-fat grafts to correct a breast affected by Poland syndrome.

Yang H, Lee H - Aesthetic Plast Surg (2010)

Morphologic analysis comparing simple centrifuged fat and squeezed fat. A (a,c,d) Left: Simple centrifuged fat. Right: Squeezed fat. bUpper: Squeezed fat. Lower: Simple centrifuged fat. B Comparative analysis of the remaining fat volumes of simple centrifuged fat versus squeezed fat. C Graph showing the percentage of the remaining fat volume after 4 and 8 weeks in simple centrifuged fat and squeezed fat, respectively
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC3104005&req=5

Fig8: Morphologic analysis comparing simple centrifuged fat and squeezed fat. A (a,c,d) Left: Simple centrifuged fat. Right: Squeezed fat. bUpper: Squeezed fat. Lower: Simple centrifuged fat. B Comparative analysis of the remaining fat volumes of simple centrifuged fat versus squeezed fat. C Graph showing the percentage of the remaining fat volume after 4 and 8 weeks in simple centrifuged fat and squeezed fat, respectively
Mentions: As a result, the survival rate for injected squeezed fat was significantly higher than for the fats of other groups (Fig. 8a–c). The average cell size in the squeezed fat was significantly smaller than in the centrifuged fat (Fig. 9a–c). It may be thought that the findings emerged by coincidence, but it is important to note the involvement of scaffolds and cell signals in the growth of undifferentiated stem cells and body tissues. Therefore, we suggest that the more destructed forms of fat tissues can be regarded as the more exaggerated experimental models of destructed fat. Gross tissue destruction usually indicates a reduction in tissue viability, but our destruction method of squeezing fat did not reduce tissue viability.Fig. 8

Bottom Line: After surgery, several small cysts and minimal calcifications were present but no significant complications.In conclusion, higher condensation of fat tissues through squeezing centrifugation would help to achieve better results in volume maintenance and reduce complications.The study experiments with squeezed fat simply suggest a hypothesis that squeezing centrifugation could select healthier cells through pressure disruption of relatively thinner membranes of larger, more vulnerable and more mature fat cells.

View Article: PubMed Central - PubMed

Affiliation: Kangnam Plastic Surgery, Shinsa-Dong 577-7, Kangnam-Gu, Seoul, South Korea.

ABSTRACT
This study attempted to reconstruct deformities of a Poland syndrome patient using autologous fat tissues. All injected fat tissues were condensed by squeezing centrifugation. Operations were performed four times with intervals over 6 months. The total injection volume was 972 ml, and the maintained volume of 628 ml was measured by means of a magnetic resonance image (MRI). The entire follow-up period was 4.5 years. After surgery, several small cysts and minimal calcifications were present but no significant complications. The cosmetic outcomes and volume maintenance rates were excellent despite the overlapped large-volume injections. In conclusion, higher condensation of fat tissues through squeezing centrifugation would help to achieve better results in volume maintenance and reduce complications. It is necessary, however, to perform more comparative studies with many clinical cases for a more scientific analysis. The study experiments with squeezed fat simply suggest a hypothesis that squeezing centrifugation could select healthier cells through pressure disruption of relatively thinner membranes of larger, more vulnerable and more mature fat cells.

Show MeSH
Related in: MedlinePlus