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Dexmedetomidine versus propofol for sedation in patients undergoing vitreoretinal surgery under sub-Tenon's anesthesia.

Ghali A, Mahfouz AK, Ihanamäki T, El Btarny AM - Saudi J Anaesth (2011)

Bottom Line: Both groups provided a similar significant reduction in heart rate and mean arterial pressure compared with baseline values.The respiratory rate values of the dexmedetomidine group were significantly higher than those in the propofol group.Dexmedetomidine at similar sedation levels with propofol was associated with equivalent hemodynamic effects, maintaining an adequate respiratory function, similar time of discharge from PACU, better analgesic properties, similar surgeon's satisfaction, and higher patient's satisfaction.

View Article: PubMed Central - PubMed

Affiliation: Department of Anaesthesiology, Magrabi Eye & Ear Hospital, Muscat, Sultanate of Oman.

ABSTRACT

Purpose: The purpose of this study was to evaluate the hemodynamic, respiratory effects, the recovery profile, surgeons, and patients satisfaction with dexmedetomidine sedation compared with those of propofol sedation in patients undergoing vitreoretinal surgery under sub-Tenon's anesthesia.

Methods: Sixty patients were enrolled in this prospective, single-blind, randomized study. The patients were divided into two groups to receive either dexmedetomidine (group D) or propofol (group P). Sedation level was titrated to a Ramsay sedation scale (RSS) of 3. Hemodynamic and respiratory effects, postoperative recovery time, analgesic effects, surgeons and patients satisfaction were assessed.

Results: Both groups provided a similar significant reduction in heart rate and mean arterial pressure compared with baseline values. The respiratory rate values of the dexmedetomidine group were significantly higher than those in the propofol group. The oxygen saturation values of the dexmedetomidine group were significantly higher than those of the propofol group. The expired CO(2) was similar in both groups. Postoperatively, the time to achieve an Aldrete score of 10 was similar in both groups. Dexmedetomidine patients have significantly lower visual analog scale for pain than propofol patients. The surgeon satisfaction with patients' sedation was similar for both groups. The patients' satisfaction was higher in the dexmedetomidine group.

Conclusion: Dexmedetomidine at similar sedation levels with propofol was associated with equivalent hemodynamic effects, maintaining an adequate respiratory function, similar time of discharge from PACU, better analgesic properties, similar surgeon's satisfaction, and higher patient's satisfaction. Thus, dexmedetomidine may prove to be a valuable adjuvant for sedation in patients undergoing vitreoretinal surgery under sub-Tenon's anesthesia.

No MeSH data available.


Related in: MedlinePlus

A 7-point Likert-like verbal rating scale for assessment of patients’ satisfaction with intraoperative sedation/analgesia
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Related In: Results  -  Collection

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Figure 0001: A 7-point Likert-like verbal rating scale for assessment of patients’ satisfaction with intraoperative sedation/analgesia

Mentions: Patients were asked to answer the question ‘How would you rate your experience with the sedation/analgesia you have received during surgery?’ using a 7-point Likert-like verbal rating scale[8] [Figure 1]. This assessment of patients’ satisfaction with sedation and analgesia was performed at 6 h after the end of surgery.


Dexmedetomidine versus propofol for sedation in patients undergoing vitreoretinal surgery under sub-Tenon's anesthesia.

Ghali A, Mahfouz AK, Ihanamäki T, El Btarny AM - Saudi J Anaesth (2011)

A 7-point Likert-like verbal rating scale for assessment of patients’ satisfaction with intraoperative sedation/analgesia
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3101751&req=5

Figure 0001: A 7-point Likert-like verbal rating scale for assessment of patients’ satisfaction with intraoperative sedation/analgesia
Mentions: Patients were asked to answer the question ‘How would you rate your experience with the sedation/analgesia you have received during surgery?’ using a 7-point Likert-like verbal rating scale[8] [Figure 1]. This assessment of patients’ satisfaction with sedation and analgesia was performed at 6 h after the end of surgery.

Bottom Line: Both groups provided a similar significant reduction in heart rate and mean arterial pressure compared with baseline values.The respiratory rate values of the dexmedetomidine group were significantly higher than those in the propofol group.Dexmedetomidine at similar sedation levels with propofol was associated with equivalent hemodynamic effects, maintaining an adequate respiratory function, similar time of discharge from PACU, better analgesic properties, similar surgeon's satisfaction, and higher patient's satisfaction.

View Article: PubMed Central - PubMed

Affiliation: Department of Anaesthesiology, Magrabi Eye & Ear Hospital, Muscat, Sultanate of Oman.

ABSTRACT

Purpose: The purpose of this study was to evaluate the hemodynamic, respiratory effects, the recovery profile, surgeons, and patients satisfaction with dexmedetomidine sedation compared with those of propofol sedation in patients undergoing vitreoretinal surgery under sub-Tenon's anesthesia.

Methods: Sixty patients were enrolled in this prospective, single-blind, randomized study. The patients were divided into two groups to receive either dexmedetomidine (group D) or propofol (group P). Sedation level was titrated to a Ramsay sedation scale (RSS) of 3. Hemodynamic and respiratory effects, postoperative recovery time, analgesic effects, surgeons and patients satisfaction were assessed.

Results: Both groups provided a similar significant reduction in heart rate and mean arterial pressure compared with baseline values. The respiratory rate values of the dexmedetomidine group were significantly higher than those in the propofol group. The oxygen saturation values of the dexmedetomidine group were significantly higher than those of the propofol group. The expired CO(2) was similar in both groups. Postoperatively, the time to achieve an Aldrete score of 10 was similar in both groups. Dexmedetomidine patients have significantly lower visual analog scale for pain than propofol patients. The surgeon satisfaction with patients' sedation was similar for both groups. The patients' satisfaction was higher in the dexmedetomidine group.

Conclusion: Dexmedetomidine at similar sedation levels with propofol was associated with equivalent hemodynamic effects, maintaining an adequate respiratory function, similar time of discharge from PACU, better analgesic properties, similar surgeon's satisfaction, and higher patient's satisfaction. Thus, dexmedetomidine may prove to be a valuable adjuvant for sedation in patients undergoing vitreoretinal surgery under sub-Tenon's anesthesia.

No MeSH data available.


Related in: MedlinePlus